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Viagra

Sildenafil is a vasoactive agent used to treat erectile dysfunction and reduce symptoms in patients with pulmonary arterial hypertension (PAH). Sildenafil elevates levels of the second messenger, cGMP, by inhibiting its breakdown via phosphodiesterase type 5 (PDE5). PDE5 is found in particularly high concentrations in the corpus cavernosum, erectile tissue of the penis. It is also found in the retina and vascular endothelium. Increased cGMP results in vasodilation which facilitates generation and maintenance of an erection. The vasodilatory effects of sildenafil also help reduce symptoms of PAH.

Other names for this medication:
Caverta, Intagra, Kamagra, Penegra, Revatio, Silagra, Sildenafil, Sildenafila, Sildenafilo, Sildenafilum, Sildigra, Suhagra, Veega, Zenegra

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Also known as: Sildenafil

Description

Viagra is an anti-impotence drug which enables men to achieve and sustain an erection. The active ingredient of Viagra is Sildenafil Citrate (PDE-5 inhibitor). In response to sexual arousal, Sildenafil Citrate stimulates the release of nitric oxide (NO) in the corpus cavernosum. Nitric oxide activates the lyase enzyme which is followed by increasing levels of cyclic guanosine monophosphate (cGMP). This cyclic nucleotide relaxes smooth muscles in blood vessels of the corpus cavernosum, increasing blood flow and thus inducing an erection. Along with the treatment of erectile disorders, Viagra effectively prolongs sexual performance, preventing premature ejaculation (PE). Sildenafil Citrate is also used in the treatment of PAH (pulmonary arterial hypertension). Viagra is also known as Aphrodil, Caverta, Kamagra, Suhagra, Edegra, Erasmo, Penegra, Revatio, Supra, Silagra, Zwagra. Viagra does not protect you or your partner from sexually transmitted diseases (including HIV) or from pregnancy.

Dosage

The starting dose is 50 mg. According to research, most men decide that 100 mg is a more effective dose if you are in a good state of health. Viagra (Pfizer) should be taken once a day, 30 minutes to 1 hour before sex. You can take Viagra (Pfizer) with or without food or alcohol. But if you want to get the quickest result you should avoid fat meals (fries or cheeseburgers) 2 hours before taking Viagra (Pfizer).

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

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Side effects

The most common side effects associated with Viagra are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Below are the cases in which Viagra is contraindicated in men:

Low/high blood pressure - sildenafil should not be used in case of severe cases of hypotension as well as hypertension. If an individual is taking medicines for hypotension or hypertension, Viagra may interact with the drug and make it ineffective.

In case of recently encountered heart attack or stroke - if an individual has recently encountered a stroke or heart attack, he must not take sildenafil as it can again trigger the condition or even make it worse.

In women, pregnancy and mothers of newborn - the drug should be used for treatment of erectile dysfunction in men. This medicine is contraindicated for use in women and pregnant mothers.

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