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Upderm (Clindamycin)

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Upderm is a strong broad-spectrum antibiotic, typically prescribed for serious infections, such as life-threatening methicillin-resistant Staphylococcus aureus (MRSA) skin infections.

Other names for this medication:
Acnestop, Antirobe, Arfarel, Bactemicina, Basocin, Bioclindax, Biodasin, Clendix, Cleorobe, Clidan, Climadan, Clinamicina, Clinbercin, Clindacne, Clindal, Clindalind, Clindamycin, Clindamycinum, Clindanil, Clindess, Clindesse, Clindoral, Clinfol, Clinidac, Clinimycin, Clinium, Cutaclin, Daclin, Dalacin, Dentomycin, Eficline, Ethidan, Euroclin, Handaramin, Indanox, Klimicin, Klindacin, Lindacyn, Lindan, Lindasol, Luoqing, Mediklin, Permycin, Toliken, Turimycin, Veldom, Velkaderm

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Also known as: Clindamycin


Clindamycin belongs to the family of medicines called antibiotics. Topical clindamycin is used to help control acne. It may be used alone or with one or more other medicines that are used on the skin or taken by mouth for acne. Topical clindamycin may also be used for other problems as determined by your doctor.

Clindamycin is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain clindamycin. It may not be specific to Upderm T. Please read with care.

Before applying this medicine, thoroughly wash the affected areas with warm water and soap, rinse well, and pat dry.

When applying the medicine, use enough to cover the affected area lightly. You should apply the medicine to the whole area usually affected by acne, not just to the pimples themselves. This will help keep new pimples from breaking out.

You should avoid washing the acne-affected areas too often. This may dry your skin and make your acne worse. Washing with a mild, bland soap 2 or 3 times a day should be enough, unless you have oily skin. If you have any questions about this, check with your doctor.

Topical clindamycin will not cure your acne. However, to help keep your acne under control, keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. You may have to continue using this medicine every day for months or even longer in some cases. If you stop using this medicine too soon, your symptoms may return. It is important that you do not miss any doses.

For patients using the topical foam form of clindamycin:

After washing or shaving, it is best to wait 30 minutes before applying this medicine. The alcohol in it may irritate freshly washed or shaved skin. This medicine contains alcohol and is flammable. Do not use near heat, near open flame, or while smoking. To apply this medicine: Do not dispense clindamycin topical foam directly onto your hands because the foam will begin to melt on contact with warm skin. Remove the clear cap. Align the black mark with the nozzle of the actuator. Hold the can upright and press firmly to dispense. Dispense amount that will cover the affected area(s) directly into the cap or onto a cool surface. The can may be placed under cold running water if the can seems warm or the foam seems runny. A small amount of topical foam should be picked up with your fingertips and massaged gently into the affected areas until the foam disappears. Unused medicine that was removed from the can should be throw away. Since this medicine contains alcohol, it will sting or burn. In addition, it has an unpleasant taste if it gets on the mouth or lips. Therefore, do not get this medicine in the eyes, nose, or mouth, or on other mucous membranes. Spread the medicine away from these areas when applying. If this medicine does get in the eyes, wash them out immediately, but carefully, with large amounts of cool tap water. If your eyes still burn or are painful, check with your doctor. It is important that you do not use this medicine more often than your doctor ordered. It may cause your skin to become too dry or irritated.

For patients using the topical solution form of clindamycin:

After washing or shaving, it is best to wait 30 minutes before applying this medicine. The alcohol in it may irritate freshly washed or shaved skin. This medicine contains alcohol and is flammable. Do not use near heat, near open flame, or while smoking. To apply this medicine: This medicine comes in a bottle with an applicator tip, which may be used to apply the medicine directly to the skin. Use the applicator with a dabbing motion instead of a rolling motion (not like a roll-on deodorant, for example). Tilt the bottle and press the tip firmly against your skin. If needed, you can make the medicine flow faster from the applicator tip by slightly increasing the pressure against the skin. If the medicine flows too fast, use less pressure. If the applicator tip becomes dry, turn the bottle upside down and press the tip several times to moisten it. Since this medicine contains alcohol, it will sting or burn. In addition, it has an unpleasant taste if it gets on the mouth or lips. Therefore, do not get this medicine in the eyes, nose, or mouth, or on other mucous membranes. Spread the medicine away from these areas when applying. If this medicine does get in the eyes, wash them out immediately, but carefully, with large amounts of cool tap water. If your eyes still burn or are painful, check with your doctor. It is important that you do not use this medicine more often than your doctor ordered. It may cause your skin to become too dry or irritated.

For patients using the topical suspension form of clindamycin:

Shake well before applying.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For topical dosage form (foam): For acne: Adults and children 12 years of age and over—Apply once a day to areas affected by acne. Infants and children up to 12 years of age—Use and dose must be determined by your doctor. For topical dosage forms (gel, solution, and suspension): For acne: Adults and children 12 years of age and over—Apply two times a day to areas affected by acne. Infants and children up to 12 years of age—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Upderm are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Upderm T if you are allergic to clindamycin or lincomycin, or if you have:

inflammation of your intestines (also called enteritis); ulcerative colitis; or if you have ever had severe diarrhea caused by antibiotic medicine.

Tell your doctor if you have ever had:

eczema or other skin problems; or an intestinal disorder.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

If you are breastfeeding, tell your doctor if you notice diaper rash, diarrhea, or signs of stomach pain in the nursing baby. If you apply clindamycin foam to your chest, avoid areas that may come into contact with the baby's mouth.

Upderm T is not approved for use by anyone younger than 12 years old.

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