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Sporanox (Itraconazole)

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Sporanox tablets and capsules are used to treat fungal infections of the toenails. Sporanox is used to treat yeast infections of the mouth and throat or of the esophagus. Sporanox is in a class of antifungals called triazoles.

Other names for this medication:
Biospore, Candiloss, Candistat, Canditral, Caritra, Citroz, Fulcover, Fungixit, Intracan, Itaspor, Itcona, Itraconazole, Itracross, Itral, Itrasig, Itrole

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Also known as: Itraconazole


Sporanox PulsePak is an antifungal medication that is used in adults to treat infections caused by fungus. This includes infections in any part of the body including the lungs, mouth or throat, toenails, or fingernails.

Some brands of itraconazole are not for use in treating fungal infections of the fingernails or toenails. Avoid medication errors by using only the brand and strength your doctor prescribes.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not share Sporanox PulsePak with another person, even if they have the same symptoms you have.

The Sporanox PulsePak capsule should be taken with food.

Swallow the capsule whole and do not crush, chew, break, or open it.

Take Sporanox PulsePak oral solution (liquid) on an empty stomach, at least 1 hour before or 2 hours after a meal. Swish the liquid in your mouth for several seconds before swallowing it.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

The Sporanox PulsePak has a special dosing schedule that includes not taking the medicine for several days in a row. Follow all dosing instructions carefully.

Sporanox PulsePak capsules should not be used in place of itraconazole oral solution (liquid) if that is what your doctor has prescribed. Avoid medication errors by using only the form and strength your doctor prescribes.

If you also take a stomach acid reducer (Tagamet, Pepcid, Axid, Zantac, and others), take Sporanox PulsePak with an acidic drink such as non-diet cola.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Sporanox PulsePak will not treat a viral infection such as the flu or a common cold.

You may need frequent medical tests.

Store at room temperature away from moisture, heat, and light.

Detailed Sporanox dosage information


If you overdose Generic Sporanox and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Sporanox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Sporanox if you are allergic to Generic Sporanox components or to itraconazole or similar medications (such as fluconazole (Diflucan) or ketoconazole (Nizoral)). Do not take Generic Sporanox if you are pregnant, planning to become pregnant, or are breast-feeding. Do not use Generic Sporanox together with nisoldipine (Sular), simvastatin (Zocor), midazolam (Versed), dofetilide (Tikosyn), ergonovine (Ergotrate), triazolam (Halcion), dihydroergotamine (D.H.E. 45, Migranal), quinidine (Quinaglute, Quinidex, Quin-Release), cisapride (Propulsid), lovastatin (Altocor, Altoprev, Mevacor), ergotamine (Ergomar), methylergonovine (Methergine), pimozide (Orap), astemizole (Hismanal), levomethadyl (Orlaam), antacids or stomach acid reducers (Tagamet, Pepcid, Axid, Zantac) within 1 hour befor or 2 hours after Generic Sporanox usage. Do not use Generic Sporanox if you have congestive heart failure. Be careful if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Be careful if you have a history of kidney or liver disease, heart disease, "Long QT syndrome", cystic fibrosis, heart rhythm disorder, history of stroke, breathing disorder. It can be dangerous to stop Generic Sporanox taking suddenly.

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Update on the status of rehabilitative countermeasures to ameliorate the effects of long-duration exposure to microgravity on vestibular and sensorimotor function. Prevention efforts for both diseases should focus on injection drug use, especially for people aged 15 to 39 years. Whole-cell patch-clamp recordings demonstrated excitatory synaptic currents with strikingly long duration and epileptiform discharge patterns, similar to waveforms observed in our human tissue samples. Paravalvular leak after transcatheter aortic valve implantation: trading one disease for another?. A histochemical study of the myocardium in staphylococcal and E. Three clinicopathogenetic variants of the disease have been identified.

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A face-to-face, 35-item survey was administered to 267 men and women residing in the Kansas City, Mo-metropolitan area. The 2 stages procedure, implying a cement spacer in the first stage and a huge bone graft in the second stage, responds to rigorous technical details involving each phase of the procedure. The efficacy of extensive resection on prolonging survival for patients with glioblastoma (GBM) is controversial because prior studies have included tumors with dissimilar resection capabilities. We show here that such aberrant ZFHX1B protein is unable to recruit NuRD subunits and displays reduced transcriptional repression activity on the XBMP4 gene promoter, a target of Zfhx1b. The extent to which tool-using animals take into account the properties of the tool is little explored. Twenty-three patients with cervical cancer were submitted to nerve-sparing Piver III RH with pelvic lymphadenectomy.


A description of an urban transitions clinic serving formerly incarcerated people. In utero exposure to di(n-butyl) phthalate and testicular dysgenesis: comparison of fetal and adult end points and their dose sensitivity. Decision-making performance is related to levels of anxiety and differential recruitment of frontostriatal areas in male rats. Thus, we need more research on basic level and clinical follow-up studies of large samples. This paper reports the only known case of a successful clinical outcome with long term oral linezolid and rifampin therapy in the management of recurrent and persistent methicillin-resistant S aureus bacteremia with metastatic infections despite prolonged vancomycin use. The 2008 Stigma Shout Survey of almost 4000 people using mental health services and carers revealed that healthcare professionals are a common source of stigma reported by people with mental illness. Histology and immunoexpression patterns were similar between primary tumors and xenografts.

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Malaria and Epstein-Barr virus (EBV) infection are cofactors in the pathogenesis of endemic Burkitt lymphoma (eBL). Semen samples were divided into two portions as follows: one portion was assessed for sperm parameters according toWorld Health Organization (WHO)-2010, while the other portion, after applying HOST procedure, was used for assessment of sperm morphology, protamine deficiency and late or early apoptosis. The main causes of fetal deaths were maternal diseases, placental and cord complications and fetal malnutrition, even though there was a decline in all these groups. In particular, we were able to define a central area that was four to six cells wide and had a low mitotic index. Morphomechanical and structural changes induced by ROCK inhibitor in breast cancer cells. A Web-based, searchable design repository captures reporting information from each project since its inception. After controlling for age, smoking, alcohol drinking, past exposure history, working hours and shift work, current exposure to solvent mixtures was significantly associated with the total number of neurological symptoms and with the prevalence of specific symptoms of the nervous system and mucous membrane irritation. Knockdown of CENP-A in HepG2 cells reduced cell proliferation, blocked cell cycle at the G1 phase, and increased apoptosis. The Impact of Altitude on Sleep-Disordered Breathing in Children Dwelling at High Altitude: A Crossover Study. The aim of this paper is to clarify the clinical and radiologic features of sternocostoclavicular hyperostosis by reviewing eight previously unpublished cases in children, identifying its similarities to chronic recurrent multifocal osteomyelitis and the differences between the pediatric and adult population affected with sternocostoclavicular hyperostosis.

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The mechanisms of ARONJ(anti-resorptive agents-related osteonecrosis of jaw)are not completely known. Induction mechanism of 2-keto-3-deoxy-gluconate metabolizing enzymes. HN1L is on chromosome 16p13.3, with three splicing in the length of 2.0, 4.0 and 4.2 kb, respectively. Despite major advances in transplant immunology and improvements in supportive and critical care medicine, HSCT is still plagued by several life-threatening complications. Our goal is to start a conversation regarding the inevitable encounter with a patient on opiates or requesting opiates.

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Features of bronchial tree sanation in patients with bronchial asthma. Preformulation studies with the Escherichia coli double mutant heat-labile toxin adjuvant for use in an oral vaccine. Encouraging reports of high agreement of ultrasonographic findings between observers, with MRI and, in knee and hip joints, histopathologic assessments were recently published. Several characteristics of emotions are that they: first, evolve dynamically over time, second, extend beyond the individual to incorporate multiple people, and third, function as a system. This report is composed of 21 consecutive patients with cervical radiculopathy who underwent a minimally invasive 2-level posterior cervical foraminotomy at our institution between 2003 and 2005. Potential psychopharmacological mechanisms explaining these differences are discussed, highlighting the importance of D2 receptor occupancy by atypical antipsychotic drugs for TD. Periodontitis is a chronic inflammatory condition of the periodontium, characterized by proinflammatory soft tissue damage and alveolar bone loss. In particular, prescriptions of opioid analgesics were infrequent. ST0838 (designed stRad55B) is one of the four RadA paralogs (or Rad55 homologues) in the genome of the hyperthermophilic crenarchaeon Sulfolobus tokodaii. The synthesis of reactive oxygen species (ROS) is one of the first events following pathogenic interactions in eukaryotic cells, and NADPH oxidases are involved in the formation of such ROS.

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A Surprising Cause for Corneal Edema after Cataract Surgery: A Missed Posterior Chamber Intraocular Lens Haptic Remnant. Reverse transcription and polymerase chain reaction (RT/PCR) with primers specific for tyrosinase allow for a new method of early detection of individual melanoma cells in peripheral blood. The results also showed that the maximum linearity with the linear phase-encoding acquisition was higher than that with the center out phase-encoding acquisition at the same R2. To evaluate the wound healing in colonic anastomosis in rats that received an hydro-alcoholic extract of Passiflora edulis peri-operatively. Because of this lack of definition in the legislation, it is unclear what critical effect values should be assessed in field studies. cAMP-induced morphological changes are counteracted by the activated RhoA small GTPase and the Rho kinase ROKalpha. However, resistance to mecillinam was more prevalent among isolates from Matlab than from Dhaka.

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In the first study, locomotor activity was assessed after 2, 4, 7, 10, and 14 days of ethanol exposure. A series of alanine peptides Ala2-Ala6 studied in their cationic states in aqueous solution at low pH displayed ROA spectra which steadily evolved toward that of OAO with increasing chain length. The uncertain status of the Mediterranean and northeastern North Atlantic fin whale subpopulations: reply to Castellote et al., Rapid Commun. Different coexisting gynecological and endometrial pathologies in postmenopausal breast cancer patients treated with tamoxifen. Eggshell ultrastructure and delivery of pharmacological inhibitors to the early embryo of R. BRCA2 is a large gene comprising 10,254 nucleotides and 26 coding exons. Moreover, the genotypic distributions between patients with HCC and without HCC were compared to investigate the association between the development of HCC and SNPs of IL-12A.

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The clinical diagnosis of cervical choriocarcinoma is difficult, because of its rarity and being non-specific abnormal vaginal bleeding the most common symptom. We investigate the effects of considering two different incoherent excitation mechanisms on microcavity quantum dot systems modeled using the Jaynes-Cummings Hamiltonian. In order to assess a possible synergistic anti-hyperalgesic interaction, the anti-hyperalgesic effects of morphine and gabapentin, single-dose administered either separately or in combination, were determined using the von Frey test in a rat model of neuropathic pain (Bennett model). Macroautophagy (herein autophagy) is an evolutionarily conserved process, requiring the gene ATG5, by which cells degrade cytoplasmic constituents and organelles. In the remaining regions, the African contribution was primarily female-mediated, whereas the European counterpart was primarily male driven and the Native American ancestry contribution was not gender biased. Biosynthesis of N,N-dimethyltryptamine (DMT) in a melanoma cell line and its metabolization by peroxidases. The spatial distribution of different elements in and on the foliage of Norway spruce growing in Switzerland. Higher blood flow rates can be applied without an increased hemolysis risk provided that needle sizes are adapted accordingly. Alpha-1-antitrypsin was significantly less in postmenopausal women with pelvic organ prolapse than in postmenopausal women without pelvic organ prolapse. In addition, the costs of recruiting IDUs into the intervention and educating them about HIV in the community was only one-thirtieth as much in the PDI as in the traditional intervention.

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Our most common fracture is a complicated injury and deserves higher status. Fibre hypertrophy was initially prominent, particularly in DMD boys until 5 years of age and in BMD patients until approximately 10 years, thereafter the mean fibre sizes became smaller than normal. Effect of maternal prenatal smoking on infant growth and development of obesity. Breast lesions in this or a similar clinical scenario should be considered malignant until proven otherwise, and a tissue diagnosis must be pursued without delay. Do mismatches between pre- and post-natal environments influence adult physiological functioning?. This indicated that the alginate lyase best accommodates a chain of six alginate residues in the active center. Laparotomy revealed a huge exophytic cystic tumor arising from the stomach. overexpression of P-glycoprotein and increase in glutathione-related detoxifying activities.

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The syndrome of conditions resulting from impingement by a prominent posterior calcaneal tubercle has been described. CPs were analyzed in food market baskets, in cooking oil/water samples (1g oil/100mL water) mixed using 16 different hand blenders, and in dismantled components of the hand blenders. However, studies on this topic are few and results have been indecisive. Our findings suggest that exposures other than to house dust mites indoors are possible sources of mite allergen exposure. The findings propose a re-evaluation of the occurrence, evolution and function of the velamen radicum in both terrestrial and epiphytic angiosperms. Data on monthly percent rabies positive (number rabid/total number tested) were available from six states and Canada. Detection of enzyme-reactant complexes by means of affinity chromatography. The purified enzyme hydrolysed soluble starch and maltooligosaccharides larger than tetraose at maltose unit, but did not hydrolyse beta-limit dextrin or p-nitrophenyl-alpha-d-glucopyranoside.

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Palivizumab: The Effects of Prophylactic Immunization on the Occurrence of Infections Caused by the Respiratory Syncytial Virus. Water-in-oil albenza cost microemulsions present themselves as an effective means of topical delivery of peptides and proteins of all sizes, and in high doses. Accuracy and Repeatability of an Anterior Segment Swept-Source Optical Coherence Tomographer. Rebound phenomena in thyroid function after withdrawal of propylthiouracil in growing chicks. The role of contact allergy in the spectrum of adverse effects caused by cosmetics and toiletries.

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Moreover, the Chinese nasal anthropometric measurements in this study are broader and flatter than those reported for North American Caucasians. In particular, we show that for large networks on which flows are influenced or generated by gradients of a scalar distributed on the nodes, scale-free structures will ensure efficient processing, whereas structures that are not scale-free, such as random graphs, will become congested. The pelvic examination revealed a classic-appearing aborting leiomyoma. The high similarity, as assessed by the mean Euclidean distance, suggests that V14337 and V14404 share the same genotype. The etiology of disease, type of resection, and 30-day morbidity and mortality were assessed. Poisoning was the commonest mode in male attempters and drug over dose in females.

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Cognitive decline has a negative impact on early postoperative morbidity and affects subjective quality of life. Although those who reported high school distress also reported more distress in young adulthood, prior psychological distress did not moderate the relationship between exposure and psychological outcomes. In Situ Phase-Transited Asymmetric Membrane Capsules: A Means for Achieving Delayed and Osmotic Release for pH Solubility-Dependant Drugs. Vascular Biology Working Group: The Canadian Initiative--Risk Intervention. Species with different spatial patterns were selected and sampled with simple random sampling, systematic sampling, linear cluster sampling and adaptive cluster sampling, whereby the accuracy of the volumetric estimation and presence of zero-plots were evaluated. All departments of medical psychology and psychotherapy, all psychosomatic societies and all psychosomatic in-patient facilities in Austria decided to participate in this network.

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Reliability coefficients were high for both methods (.90 and .96, respectively, for accuracy, and .87 and .95, respectively, for response time measures), but Web-based participants produced consistently lower overall scores. We previously developed a procedure to predict the drug effect on the menopausal depressive-like state in female mice. Pharmacological and kinetic characterization of adrenomedullin 1 and calcitonin gene-related peptide 1 receptor reporter cell lines. This paper reviews the evolution of rotational angiography and advanced 3D X-ray imaging applications to interventional cardiology. The device sensitivities observed were 0.2656 microA/mM for cholesterol, 0.15354 mA/mM for bilirubin, 0.13698 microA/(U/l) for alanine aminotransferase (ALT) and 0.45439 microA/(U/l) for aspartate aminotransferase (AST). Four psychiatrists with expertise in the pharmacotherapy of panic disorder and experience working in the primary care setting reviewed the available treatment literature and developed a consensus treatment algorithm for norvasc amlodipine with alcohol panic pharmacotherapy in the primary care setting.

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Immunisation of cattle with antigens expressed in the sporozoite, schizont or merozoite stages has resulted in varying degrees of protection against challenge. The proposed method is applied to RT-PC flow MRI based on highly undersampled acquisitions. Mutagenesis of a positively charged arginine at the cytoplasmic mouth of the pore, Arg303, leads to significant weakening of the blocking effects of suramin, a large negatively charged organic molecule. Moreover, the average compositions of Cu ranged from 3.00 to 148 mg/kg, and the average compositions of Ni ranged from 1.00 to 37.4 mg/kg. Here, we provide a wide comparison of mGBPs roles within the host cell in the context of Chlamydia and Toxoplasma infection.

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Potentiating and inhibiting effects of steroid hormones on the incidence of 90Sr induced osteosarcoma. Both receptors have additional functions that are currently being unraveled. The prominence of peripheral neuropathy as a cause of the restless legs syndrome in CMT may justify treatment with neuropathic medications as opposed to the more commonly recommended dopaminergic agents. These novel biochemical markers are not clinically useful in predicting spontaneously resolving PULs. Successful treatment of recurrent focal segmental glomerulosclerosis with a low dose rituximab in a kidney transplant recipient. We found that knockdown of autophagy, in combination with tamoxifen in MCF7 cells, results in decreased cell viability concomitant with increased mitochondrial-mediated apoptosis. However calculated, the LDs over the chosen (membrane and organelle) compartments are used to obtain observed and expected gold particle counts.

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Trimester-Specific Reference Intervals of Thyroid Function Testing in Pregnant Women from Basrah, Iraq Using Electrochemiluminescent Immunoassay. Local Protocol Variations for Image Guided Radiation Therapy in the Multicenter Dutch Hypofractionation (HYPRO) Trial: Impact of Rectal Balloon and MRI Delineation on Anorectal Dose and Gastrointestinal Toxicity Levels. Future studies should consider the use of incentives, reminder systems, and other strategies to enhance website usage. Two patients developed slight hypertension in the postoperative period, which resolved within 24 h, and four patients theolair drug information developed moderate corneal edema persisting for 1-2 days postoperation. Multiple regression models of BMC and BMC/BW on age, weight/height and skin reflectance yielded significant correlations ranging from 0.62 to 0.77, but the partial coefficients for skin reflectance were not significant.

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Furthermore, intracerebroventricular administration of BDNF triggered an immediate neuronal response in multiple hypothalamic nuclei in wild-type mice, suggesting that its anorexigenic actions involve short-term mechanisms. Combined hinge flap full-thickness skin graft for a through-and-through nasal defect. We sought to determine the postoperative management, incidence of tumor recurrence in the neck, and outcome in laryngeal cancer patients whose risk for tumor relapse is not clear. These signs are consistent with the propensity of adult-onset Alexander disease to cause medullary abnormalities on neuroimaging. The difference observed between SIP-pos and SIP-neg rats were entirely condition-specific, since they disappeared in the absence of access to water. The fates of more than 300 pesticide residues were investigated in the course of beer brewing. The second transformation calculates the tip deflection due to applied forces and is efficiently computed using the special Cosserat rod model.

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The majority of the FTR conjugate internalized by proximal tubules accumulated within a lysosomal pool, as determined by colocalization studies. The present study, carried out in a hospital environment, concerns 182 cases of valve cardiopathies hospitalized in the Cardiology Department of the University Hospital Ignace-Deen between January 1, 1981 and December 31, 1987. Suggested conduct by the Argentine Circle of Digestive Motility for the management of gastroesophageal reflux disease. Even though ODF2 is the main isoform in testicular tissue RT-PCR analyses revealed that isoforms are not restricted to specific tissues. Norethisterone (NET), one of progestins, has safety profile and advantage that allow long-term use.

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Point-contact transport properties of strongly correlated electrons on liquid helium. The optically induced electron dynamics at a Si(001) surface is studied using a five-wave-mixing setup which measures the diffracted second-harmonic intensity induced by three ultrashort (13 fs) laser pulses. At 6 days post-infection (p.i.), adult worms were detected in the small intestine of reptiles infected with T. To examine further the consequences of the substitution of conserved aspartate 152 on the function of the GH receptor (GHR), we reproduced the mutation in vitro on the full length GH receptor cDNA from man and rat. Log-rank and Cox methods were used for univariate and multivariate analyses, respectively. Multi-Source Multi-Target Dictionary Learning for Prediction of Cognitive casodex medication chemotherapy Decline. Simultaneous determination of glutathione and cysteine concentrations and 2H enrichments in microvolumes of neonatal blood using gas chromatography-mass spectrometry. In parallel, molecular dynamics simulations further confirm that buried water in GH has the stronger interaction with pollutants via hydrogen bonds than other buried alcohols.

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Compared to the control condition, P300 amplitude decreased after high-intensity pedaling exercise and increased after medium-intensity pedaling exercise. In all patients, arthroscopy was performed within 2 months after the MR examination. We used fMRI with 28 healthy young and older adults on an inhibitory control task. Antibodies against the fibrinogen binding protein (Fbe) of Staphylococcus epidermidis significantly increased macrophage phagocytosis. In vitro studies with bone cell cultures have demonstrated that the bone-resorptive activity of PGE(2), which is mediated by receptor activator of NF-kappaB ligand (RANKL), is key for the induction of osteoclast formation. Outcomes of hypoxic-ischemic encephalopathy in neonates treated with hypothermia. Early experience with direct transatrial balloon-expandable implantation for severe mitral annular calcification revealed feasibility of this approach but significant morbidity and mortality primarily related to periprosthetic regurgitation that requires further refinement of the technique. In the four cases of oligohydramnios with rupture of membranes, one case had a healthy full-term baby delivered. Only controlled studies comparing a fixed bearing with a mobile bearing type of TKP were considered.

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