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Prometrium (Progesterone)

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Prometrium contains the hormone progesterone. It regulates menstrual periods by helping to balance the natural levels of the hormone progesterone in the body. When taken together with estrogen-containing medications, it helps protect the uterus from the damage caused by estrogen.

Other names for this medication:
Corion, Cygest, Durbagest, Durogest, Egeria, Endogest, Evagest, Forgest, Gester, Gestmate, Hormorin, Isogest, Lutacare, Lutamax, Macgest, Minagest, Miprogen, Nidagen, Orgasest, Powergest, Pregcitil, Pregzed, Progesterone, Progez, Promyzz, Pyrtex, Rigest, Rimgest, Rivgest, Sperogest, Strone, Theragest, Truegest, Vageston, Wongest

Similar Products:
Epivir, Luvox, Levothroid, Panadol, Plavix, Ceftin, Coreg, Lopid, Fertisafe, Carebet, Tgmet, Estraderm, Neurontin,

Also known as: Progesterone


Prometrium is a female hormone important for the regulation of ovulation and menstruation.

Prometrium is used to cause menstrual periods in women who have not yet reached menopause but are not having periods due to a lack of progesterone in the body. This medicine is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.

Prometrium should not be used to prevent heart disease or dementia, because Prometrium may actually increase your risk of developing these conditions.


Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

Take the Prometrium capsule with a full glass of water. It is best to take the medicine at night because this medicine can make you dizzy or drowsy.

Apply Prometrium cream to the skin as directed by your doctor.

Prometrium is sometimes used for only a short time, such as 10 to 12 days during each menstrual cycle. Follow your doctor's dosing instructions very carefully.

Have regular physical exams and self-examine your breasts for lumps on a monthly basis while using Prometrium.

If you need surgery or medical tests or if you will be on bed rest, you may need to stop using this medicine for a short time. Any doctor or surgeon who treats you should know that you are using Prometrium.

Store at room temperature away from moisture, heat, and light.

Detailed Prometrium dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Prometrium dosage information

Side effects

The most common side effects associated with Prometrium are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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