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Ovral (Norgestrel)

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Ovral is a contraceptive medicine that stops you from getting pregnant in multiple ways. Firstly, it prevents an egg from being released from your ovaries. Secondly, it makes the fluid (mucus) in your cervix thicker, which makes it more difficult for sperm to enter the womb.

Other names for this medication:

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Also known as: Norgestrel


Lo/Ovral-28 contains a combination of ethinyl estradiol and norgestrel. Ethinyl estradiol and norgestrel are female hormones that prevent ovulation (the release of an egg from an ovary). Lo/Ovral-28 also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Lo/Ovral-28 is used as contraception to prevent pregnancy.


It is very important that you use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

This medicine is available in blister packs. Each blister pack contains 28 tablets with different colors that need to be taken in the same order as directed on the blister pack.

When you begin using this medicine, your body will require at least 7 days to adjust before a pregnancy will be prevented. Use a second form of contraception (eg, condom, spermicide, or diaphragm) for the first 7 days of your first cycle of pills.

Take this medicine at the same time each day. Birth control pills work best when no more than 24 hours pass between doses.

Do not skip or delay taking your pill by more than 24 hours. If you miss a dose, you could get pregnant. Ask your doctor for ways to help you remember to take your pills or about using another method of birth control.

You may have light bleeding or spotting when you first take the pill.

You may feel sick or nauseous, especially during the first few months that you take this medicine. If your nausea is continuous and does not go away, call your doctor.

If you vomit or have diarrhea within 3 to 4 hours of taking this medicine, treat this as a missed dose and follow the instructions in the patient leaflet or call your doctor.

If you are switching from another birth control method to using Lo/Ovral®:

Transdermal patch, vaginal ring, implant, or injection—Start Lo/Ovral® on the day that you would usually apply, insert, or inject the medicine. Intrauterine device (IUD)—Start Lo/Ovral® on the day of removing the IUD. Use a second form of birth control for the first 7 days if the IUD has not been removed on the first day of your menstrual cycle.

If you have a miscarriage or an abortion in the first trimester of your pregnancy, you may start using this medicine right away. You do not need a second form of birth control. If you start this medicine 5 days or more after the miscarriage or abortion, you should use a second form of non-hormonal birth control for the first 7 days of your first pill cycle. If you have a miscarriage or abortion after the second trimester, you should wait for 4 weeks before starting this medicine. Use another form of birth control for the first 7 days of your first pill cycle if you use this medicine on a Sunday.

Do not drink grapefruit juice while you are using this medicine. Grapefruit juice may change the amount of this medicine that is absorbed in the body.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Your doctor may ask you to begin your dose on the first day of your menstrual period (called Day 1 Start) or on the first Sunday after your menstrual period starts (called Sunday Start). When you begin on a certain day, it is important that you follow that schedule, even if you miss a dose. Do not change your schedule on your own. If the schedule that you use is not convenient, check with your doctor about changing it. For a Sunday start, you need to use another form of birth control (eg, condom, diaphragm, spermicide) for the first 7 days.

For oral dosage forms (tablets): For contraception (to prevent pregnancy): Adults and teenagers—One white tablet (active) taken at the same time each day for 21 consecutive days followed by one brown (inert) tablet daily for 7 days per menstrual cycle. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, and vaginal bleeding.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Ovral dosage information

Side effects

The most common side effects associated with Ovral are:

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Extremely low frequency-EMF exposure with the flux intensities between 1-5 microT for 40 days did not cause any effect on the relative spleen weight, lymphoid organ histology, leukocyte and ANAE-positive lymphocyte percentages of the mouse. Validation of catheter segmentation for MR-guided gynecologic cancer brachytherapy. High levels of lead enrichment were found in the upper 0-5 cm soil layer along roads with heavy traffic loads. Research often assumes that, in rural areas of developing countries, adverse climatic conditions increase (climate driver mechanism) rather than reduce (climate inhibitor mechanism) migration, and that the impact of climate on migration is moderated by changes in agricultural productivity (agricultural pathway). Remitting seronegative syndrome with pitting edema as the presenting symptom in a young, male patient with sarcoidosis: a case report. Ubc9 is an E2-conjugating enzyme required for sumoylation and has been implicated in regulating several critical cellular pathways. In addition, the importance of template immobilization for successful protein imprinting had also been illustrated to demonstrate the potential of this approach as a general methodology for protein imprinting. In the cryptorchidism group the same differences are found in fertile and infertile men.

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Effect of arachidene, a preparation of unsaturated fatty acids, on the blood coagulation and anticoagulation systems in patients with coronary arteriosclerosis. At the increasing of age, the velocity and acceleration of the postural sway measurements are increasing, but they decrease when the noise are introduced. Lung, liver, heart and spleen samples were cultured, and homogenates of lung and liver were used to detect the number of colony-forming units per gram. The present results provide a basis for relating CRALBP domains with physiological function and for the future development of a more detailed three-dimensional model of the interaction of 11-cis-retinaldehyde with protein. There is an urgent need for randomised studies to address the use of mechanical devices in comparison with no treatment, surgery and conservative measures. In this study three different types of industrial activities in a steel plant have been studied in Thailand. Histology alone is an insufficient indicator to answer our question and definitive tab maxolon in pregnancy understanding of the prolapsed tissue may result from a randomised study on a larger study population. The findings of well-defined margin and low density nodular area in CT image may suggest benign thyroid lesions, whereas the presence of irregular border, granular calcifications and cervical lymph node enlargement as well as complex density may indicate thyroid malignancy.

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