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Metronid (Metronidazole)
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Metronid

Metronid belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

Other names for this medication:
Acuzole, Amevan, Amrizole, Anamet, Aristogyl, Biatron, Diazole, Dumozol, Flazole, Flegyl, Giardyl, Ginkan, Gynomix, Litagyl, Mecozol, Metren, Metris, Metrocream, Metrogel, Metronidazols, Metroson, Metrozole, Negazole, Nizole, Onida, Padet, Promuba, Robaz, Rosaced, Servizol, Tolbin, Trichex, Trichodazol, Triconex, Vagilen, Vagizol, Wingyl

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Also known as: Metronidazole

Description

Metronidazole vaginal is used to treat women with vaginal infections (eg, bacterial vaginosis).

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing the bacteria or preventing their growth. However, this medicine will not work for vaginal fungus or yeast infections.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Metronid. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine is to be used only in the vagina. Use it at bedtime, unless your doctor tells you otherwise.

Do not get it into your eyes, nose, mouth, or skin. If this medicine does get into your eyes, wash them out right away with large amounts of cool tap water. If your eyes still burn or are painful, check with your doctor.

This medicine comes with a patient information leaflet and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Wash your hands with soap and water before and after using this medicine.

Nuvessa™ is available inside a prefilled applicator. The applicator is open at one end where you will insert the plunger and has a pink cap on the other end where the medicine will come out.

Vandazole® is in a tube. You will use an applicator to put the gel into your vagina. The applicator has a plastic tube called a barrel that is open at one end and has a plunger (another piece of plastic that can move inside the barrel) at the other end.

To use the medicine:

To fill the applicator: For cream or gel dosage forms: Nuvessa™: With the pink cap still on, push the tip of the plunger into the open end of the prefilled applicator. Pull the cap off before you insert the applicator into your vagina. Vandazole®: Break the metal seal at the opening of the tube by using the point on the top of the cap. Screw the applicator onto the tube. Squeeze the medicine into the applicator slowly until it is full. Remove the applicator from the tube. Replace the cap on the tube. For vaginal tablet dosage form: Place the vaginal tablet into the applicator. Wet the vaginal tablet with water for a few seconds. To insert vaginal metronidazole using the applicator: For all dosage forms: Relax while lying on your back with your knees bent (or in any position that you feel comfortable). Hold the full applicator in one hand. Insert it slowly into the vagina. Stop before it becomes uncomfortable. Slowly press the plunger until it stops. Withdraw the applicator. The medicine will be left behind in the vagina. Remove the applicator from your vagina. Use each applicator only once, and then throw it away.

To help clear up your infection completely, it is very important that you keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses. Also, continue using this medicine even if your menstrual period starts during the time of treatment.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For bacterial vaginal infections: For vaginal dosage form (cream): Adults—One applicatorful (500 milligrams [mg]), inserted into the vagina. Use the medicine 1 or 2 times a day for 10 or 20 days. Children—Use and dose must be determined by your doctor. For vaginal dosage form (gel): Nuvessa™: Adults and children 12 years of age and older—One applicatorful (5 grams [g]) inserted into the vagina once (at bedtime). Each applicatorful of Nuvessa™ contains 65 mg of metronidazole. Children younger than 12 years of age—Use and dose must be determined by your doctor. Vandazole®: Adults—One applicatorful (5 grams [g]) inserted into the vagina once a day (at bedtime) for 5 days. Each applicatorful of Vandazole® contains 37.5 mg of metronidazole. Children—Use and dose must be determined by your doctor. For vaginal dosage form (tablets): Adults—One 500 milligram (mg) tablet, inserted high into the vagina. Use the medicine once a day in the evening for 10 or 20 days. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Metronid and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Metronid overdosage: dizziness, seizures, torpor, retching, nausea, lack of balance, problems with coordination, tingling.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Metronid dosage information

Side effects

The most common side effects associated with Metronid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Introduction of a concise identifier system allows easy generation of pedigree trees. By contrast, the regulated cleavage of LAMP-2A at the lysosomal membrane is reduced owing to altered association of the receptor and the protease responsible for its cleavage to particular membrane microdomain regions. Thus, mcd(-/-) mice exhibit reduced rates of fat catabolism and resist diet-induced glucose intolerance despite high intramuscular levels of long-chain acyl-CoAs. A crucial problem in the non-operative diagnosis of thyroid nodules is the significant amount of non-diagnostic biopsies. Therefore, Ent3p and Ent5p are the first proteins shown to be connectors between PtdIns(3,5)P(2)- and the Vps27p-ubiquitin-driven sorting machinery at the multivesicular body. Urographic and angiographic abnormalities in adult-onset acute bacterial nephritis. Considering that bleeding risk did not differ significantly between ESD and EMR and that perforation risk usually does not lead to life-threatening disease, the effectiveness benefit of ESD can outweigh the overall harm compared with EMR on the condition that ESD is performed by experienced practitioners. SEM of the mutant strain clearly showed that the overproduced biofilm contained a filamentous structure.

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We review herein the rationales underlying each derivation, and the strengths and fields of application of both strategies. The whole brain cholinesterase activity of small feral mammals was approximately 2 to 5 fold greater than the domestic animals. A full simulation set-up for molecular optical imaging (bioluminescence and fluorescence) is implemented in GATE, and images of the light distribution emitted from a phantom demonstrate the relevance of using GATE for optical imaging simulations. A brief review of thrombo-cytopenic purpura associated with brucellosis is presented. Piecewise isometries (PWIs) are known to have dynamical properties that generate interesting geometric planar packings. Problems and re-evaluation of quantitative determination of carbon monoxide in the blood. Flow of information and gene activation during antibody synthesis.

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Leaving former residence, more care and help given by both the family and the society and raising their overall quality of life are the demands of abstainers. Overexpression of CREB reduces CRE-mediated transcription: behavioral and cellular analyses in transgenic mice. Development of resistance to eCry3.1Ab-expressing transgenic maize in a laboratory-selected population of western corn rootworm (Coleoptera: Chrysomelidae). Attacks by jaguars (Panthera onca) on humans in central Brazil: report of three cases, with observation of a death. We also describe demographic, clinical and imaging findings, staging, and treatment options. Extraction of pectin from Premna microphylla turcz leaves and its physicochemical properties. Although we utilized IPW to reduce the impact of paternal reporting bias, our estimates may still be influenced by the missing data in the NVSS.

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In children and older adults undetected food-drug interactions may lead to serious morbidity and mortality and be misdiagnosed as chronic disease progression. The authors describe a case of plica neuropathica in a paranoid schizophrenic patient who developed irreversible tangling of scalp hair. Electrical response of a medium containing dissociable impurities. Cranberry is a traditional folk remedy for cystitis and, which, in the form of a variety of products and formulations has over several decades undergone extensive evaluation for the management of urinary tract infections (UTI). In CRCP, prostate cancer cells still rely on intracellular androgens and, to a greater extent, on active AR for growth and survival. Data were collected on all Full-Length Articles and Brief Reports submitted to the AJO. In this group of targets, the c-Met receptor tyrosine kinase plays an important role in increased cell growth, reduced apoptosis, altered cytoskeletal function, increased metastasis, and other biologic changes.

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The Potential and Challenges of Exploiting the Vast But Dynamic Neoepitope Landscape for Immunotherapy. Data for the prevalence of headache were drawn from the database of seven representative surveys in the SERMO study (Self-Reported Morbidity Study). Late clinical, biochemical, endoscopic and electroencephalographic evaluation of patients with schistosomal portal hypertension treated with distal splenorenal shunt. We compared Bayer VERSANT HBV DNA 3.0 Assay (VERSANT 3.0) with Digene Hybrid Capture II HBV DNA Test (HC-II) according to HBeAg status and ALT levels in 232 HBV-infected Korean patients. Hunger control with benzphetamine hydrochloride in the treatment of obesity.

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The modified Kasr El Aini sexual assessment sheet assesses sexuality. A research domain to invest: how to avoid the blindness of millions of patients who are not cured by palpebral surgery in the case of trichiasis related to trachoma. Hepatic phosphorylase b kinase deficiency with normal enzyme activity in leukocytes. Taken together, these observations suggest that in Francisella MglA and MglB may affect the expression of genes whose products contribute to survival and growth within macrophages. Single-stage surgical repair of airway gastric fistula after esophagectomy. The sample size was considered 60 patients with 30 subjects in each group. The current debate on induced abortion and the age when a young woman is considered mature to have this without parental consent, shows the need to know the real importance of adolescent pregnancy in the Emergency Department. Leiomyosarcoma of prostate is a rare, aggressive tumor with bizarre presentation at advanced stage. The incidence and course of neuropsychiatric symptoms were determined in pediatric patients with rheumatic fever.

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In three experiments, cost-benefit analysis was used to determine the role of attention in the processing of auditory information. It may be applicable to newly emerging related viruses or variants. Taken together, the data do not support a role for the metabolic activation of DES in this tumor model. The HIV epidemic is also likely to have an indirect effect on the incidence of tuberculosis because of the increased number of infectious individuals in the population. Oropharyngeal morbidity following transoral approaches to the upper cervical spine.

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One hundred eyes of 100 normal subjects of both sexes, aged 19 to 76 years, underwent anterior segment evaluation by AS OCT (Visante OCT). We demonstrate clear evidence for marked macro- and microvascular injury. A Turing pattern formation was observed with the addition of n-dodecyltrimethylammonium bromide. We excluded all of the references and found no randomised clinical trials investigating treatment of blunt pancreatic trauma in children. The study demonstrated a transient hemodynamic effect of heat-based stimulation distinct to that of TILS. RCT evidence exists that certain strategies improve adherence to anti-tuberculous therapy, and these should be adopted into clinical practice depending on their appropriateness to practice circumstances. A rapid infectivity assay is key to confirming positives in human samples, and dilutions of infected human brain will probably provide adequate routine control samples to ensure the correct performance of the test. Despite a high proportion of TV/screen time, children were also engaged in a range of other sedentary and physically active pursuits after school. The only postoperative complication was subcutaneous emphysema, which could be minimized by suctioning excess CO2 from the abdomen at completion of surgery. Aldosterone and its mineralocorticoid receptor represent an ancient signaling system.

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Baseline mRNA levels were of greatest abundance for matrix proteins and lowest for proteases. Complications from intubation were minimal and none were seen related to regional blockade. Two months later, radiograph, radionuclide bone scan, and magnetic resonance imaging (MR) of the involved hip were positive for aseptic necrosis of the femoral head. Allopurinol does not produce additional antihypertensive effects in patients with treated arterial hypertension. The initial AaDO2 were similar in both the groups but on day 3, 4, 5 AaDO2 were low in study group (201, 85, 70) compared to control group (236, 209, 162).

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T3 (1.5 nmol/l) inhibited GH release and had no effect on TSH secretion. An observational study of screening for malnutrition in elderly people living in sheltered accommodation. Evaluation of molecular typing methods for Escherichia coli O157:H7 isolates from cattle, food, and humans. However, in contrast to commonly used 2D static cell culture in multiwell plates, our new system allows 3D perfused cell culture. The reduced rate of MT elongation, associated with reduced recruitment of end-binding (EB) proteins to plus ends, was alleviated by expression of truncated N-cadherin, but was only moderately affected when actomyosin was disrupted.

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Surface concentrations and denaturation rates of adsorbed cyt c are dictated by specific manipulation of the individual MPCs composing the outer layer of the film. Three reviewers independently evaluated all potentially relevant articles, examined each study for possible inclusion and assessed the methodology quality using the Cochrane guidelines. Further asexual development of Eimeria magna merozoites in cell cultures. Transbronchial brush cytology and a biopsy failed to collect tumor cells but transbronchial fine-needle aspiration (FNA) cytology was successful. Biomechanics studies on the combined effects of high-heeled shoe wearing and asymmetrical load carrying are lacking. The patient had traveled to a jungle area of Belize several hours drive from the capital city. The NLCA could efficiently differentiate the cognitive impairment patients from the normal controls and is a reliable and valid cognitive assessment test battery to specially find nonlinguistic cognitive function for aphasic patients. In addition, the risk of acidosis is higher in patients with impaired renal function. The fountain effect of ice-like water across nanotubes at room temperature.

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Collectively, these data suggest that NAcc shell neurons encode cues associated with natural reward, are less responsive during appetitive behavior in familiar conditions, and are insensitive to appetitive learning differences expressed in rats reared in different environmental conditions. Unusual ending of the second dorsal metacarpal artery as proper palmar digital arteries. Extension teardrop fracture of the axis is an extremely rare cervical spinal injury. The patient was a 66-year-old woman with obstructive jaundice, in whom computed tomography confirmed that gallbladder carcinoma had invaded the liver and that massive lymph node metastases involved the hepatoduodenal ligament. DMMC inhibited the activity of calmodulin-dependent kinase III and protein kinase A very weakly, and only barely affected protein kinase C activity. The Hybrid model was used for analysis according to the 3 phases.

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One of the primary obstacles in the restoration or repair of damaged tissues is the temporospatial orchestration of biological and physiological events. A major advantage of this metamorphosis model is its total dependence on thyroid hormone (T3). Local treatment of leg disorders and chronic venous insufficiency. The significance of this pathway was confirmed using functionally deficient cells, TALEN-mediated gene disruption, RNA interference and pharmacologic inhibition. Noninvasive topical loading for manganese-enhanced MRI of the mouse visual system. The present study shows that there were no obvious findings to support the hypothesis that low-intensity pulsed ultrasound enhances bone healing in self-reinforced poly-L-lactide (SR-PLLA) rod fixed experimental metaphyseal distal femur osteotomy in rats.

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Some 82 women were assigned to the traditionally fed group and 97 women were assigned to the early fed group. Careful application and fixing of omentum to denuded surfaces appears important, it ensures these features by prevention of scarring and adhesion formation. The right ureter was electrocauterized and transsected, and the left ureter was ligated. Protocol of a randomised controlled trial characterising the immune responses induced by varicella-zoster virus (VZV) vaccination in healthy Kenyan women: setting the stage for a potential VZV-based HIV vaccine. Thereby the initially straight heart tube curves toward its original ventral side and the resulting bend becomes displaced toward the right side of the embryo. Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. Following the prediction that the gene encodes one or more acyltransferases, lipid studies have shown a deficiency of cardiolipin, especially its tetralinoleoyl form (L(4)-CL). To evaluate the effect of a bridge safety fence in preventing suicide. Our results suggest that a novel function of heparanase upon cell differentiation would raise a potential new strategy for cancer therapy of promyeloid leukemia and other types of cancer. Pax7 transcripts, present before differentiation in committed C2C12 cells, but absent in uncommitted MSCs, increased noticeably in MSCs after differentiation.

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The heterocyclic skeleton together with the carbonyl oxygen and harga obat piroxicam gel the methyl carbon is planar, and only small angle distortions occurred. Caveolin-1 and force regulation in porcine airway smooth muscle. The RSultr3.2A gene encodes a polypeptide of 651 amino acids with a calculated molecular mass of 71701 Da. EMG of trapezius and latissimus dorsalis and 3D kinematic recordings of the left scapula were analysed. parasitica isolates on Arabidopsis accessions, we developed a novel delivery system using Pseudomonas syringae type III secretion via fusions of ATRs to the N terminus of the P.

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We found significant improvements in positive approach-coping, caring-cooperative behavior, suppression of aggression, and consideration of others, but no changes in aggressive-antisocial behaviors. These results show that a functional receptor indeed exists in human epidermis. Following recognition of the damage, the sub-pathways then converge for the incision/excision steps and subsequent gap filling and ligation steps. Multiple soliton bound states and symmetry breaking in quadratic media. The structure-activity profile of these drugs and implications of drug combinations are discussed.

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Glaucomatous damage to the ganglion cell layer might be particularly harmful to melanopsin. Clinical Data Management Systems (CDMS) are specialized software solutions geared toward GCP-trials. Threshold and adaptation properties were related to the receptor position relative to the fulcrum and apex of the tooth. can i use flonase with sinus infection Of the studied alternatives, the multiplicative method and a variance model with a random herd-year effect were found most suitable for the Nordic test-day model for dairy cattle evaluation. To determine whether testing in vitro of combinations of anti-thrombotic agents can identify potentially important interactions, we evaluated the combination of rNAPc2 with antagonists of platelet GP IIb-IIIa to identify potentially altered anticoagulant properties, antiplatelet effects, or both.

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Introduction of the human growth hormone (hGH) gene fused with mouse metallothionein I promoter into domestic mice leads to ectopic synthesis of hGH, marked stimulation of somatic growth, and female sterility. Rheumatic manifestations were highly frequent in HIV patients receiving HAART referred to a rheumatology clinic, although the clinical spectrum differed from the pre-HAART era with septic and malignant complications being the most common manifestations seen. Compared to ICBT, SES implantation for diffuse bare metal ISR showed less late loss, lower restenosis, and a trend toward lower 1-year MACEs. The nutritional risk was assessed by NRS-2002 and the nutritional status by Subjective Global Assessment (SGA), Mini-Nutritional Assessment (MNA long form), calf circumference (CC), and body mass index (BMI). A novel cellular senescence gene, SENEX, is involved in peripheral regulatory T cells accumulation in aged urinary bladder cancer. An efficient algorithm for modeling dispersive media in finite-difference time-domain methods is presented. We conclude that UVB irradiation of recipient before or after transplantation has a preventive effect on cutaneous Scl GVHD and may represent an effective strategy for prevention of Scl GVHD. There is no significant advantage of 1-stage posterior corpectomy over decompression with fusion.

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Intubation according to the Gorback technique in a case of hypertrophy of the coronoid apophysis. The closed-form solution is proposed so that no iterative numerical calculation is required. The number of clonal precursors of the follicular epithelium in the mouse ovary. Further groups of 3-week-old Mdr2(-/-) mice were treated with rapamycin and irbesartan in combination (1 mg/kg/day and 10 mg/kg/day) or with rapamycin (2 mg/kg/day) for 4 weeks. Saffron (Crocus sativus L.) is a common but very expensive herbal medicine. If a new virtual object is created for each new service request, then the number of virtual object would increase exponentially. Cyclical carotid artery flow reduction in conscious dogs: effect of a new thromboxane receptor antagonist. In this review, management and surgical indications of thyroid nodules and parathyroid adenomas are discussed. Significance and possibilities of histopathologic diagnosis in breed-specific skin diseases.

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We propose an additional trace distance measure for the information flow that could be extended to other master equations. Production of polyethylene wear from acetabular liners is thought, in part, to mediate the periprosthetic osteolysis. Haritaki (Terminalia chebula Retz., Family: Combretaceae) possesses a great therapeutic value and is widely distributed in India, up to an altitude of 1500 m. However, its expression correlated with cancer aggressiveness and poor outcome in high-grade bladder cancer. Explanations of the bias effect in terms of lexical activation and episodic memory retrieval are discussed. Renin production is under physiological control and can be influenced by ACTH, changes in electrolyte balance and the genetic background of the rat. Insemination of the monogenean Neobenedenia girellae (Capsalidae, Benedeniinae).

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These results lead us to hypothesize that periadolescent MDMA exposure alters responsiveness to the rewarding properties of morphine, highlighting MDMA as a gateway drug whose use may increase the likelihood of dependence on other drugs. Two full surveys of four villages in Mwanza, Tanzania were completed over consecutive years, 2010-2011. When both tasks were lateralized to the same hemisphere (digits and right-hand tapping or spatial locations and left-hand tapping), highest memory task intercorrelations (Experiment 1) and better retention of sequences (Experiments 1 and 2) resulted. Modulated expression of the epidermal growth factor-like homeotic protein dlk influences stromal-cell-pre-B-cell interactions, stromal cell adipogenesis, and pre-B-cell interleukin-7 requirements. The adjective neurodegenerative came in vogue in neurology and was mostly applied is zyrtec allergy medicine to brain diseases. Parasitized and non-parasitized 2nd-instar larvae of the fall armyworm were tested for susceptibility to chlorpyriphos, methomyl, cypermethrin, and Bacillus thuringiensis in the laboratory, using the leaf dip test.

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There was no apparent relationship between potency/affinity at CRF2 receptors and effects in these two tests. Moreover, combination therapy is associated with a higher toxicity rate and poor quality of life. Diurnal variations of VOCs at the border of the city area, receiving domestic and industrial discharges, provided information to interpret their observed downstream distribution amaryl 2mg tablets and possible sources. There were few consistent effects of perceived social support on psychological impairment. The media analysis documents an absence of reflection of the social determinants viewpoint on these, the most important causes of disease and death. Interactions of PCBs with human serum albumin: in vitro spectroscopic study. During scan sessions before and after SSA learning, subjects were presented with visual images and auditory soundscapes. Edible alginate-based coating as carrier of antimicrobials to improve shelf-life and safety of fresh-cut melon. The system was originally designed for biomedical research in chemotherapy (predicative chemotherapy assays) and pharmacology but it turned out to be also an effective tool for toxicological and environmental research. We used administrative hospital discharge data from a large Canadian city for all cases with acute MI coded as most responsible diagnosis between January 1, 1995, and March 31, 2001.

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