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Lipitor

Lipitor is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Lipitor is indicated for the treatment of several types of dyslipidemias, including primary hyperlipidemia and mixed dyslipidemia in adults, hypertriglyceridemia, primary dysbetalipoproteinemia, homozygous familial hypercholesterolemia, and heterozygous familial hypercholesterolemia in adolescent patients with failed dietary modifications.

Other names for this medication:
Alipid, Anvistat, Atacor, Atasin, Atenfar, Ateroz, Atocor, Atorsan, Atorvastatin, Atorvox, Atova, Atovarol, Avascare, Avastatin, Aztor, Biostatina, Caduet, Dislipat, Divastin, Divator, Hypolip, Liparex, Lipibec, Lipicon, Lipidra, Lipinor, Lipitin, Lipobi, Lipodial, Liponorm, Lipovast, Locol, Lorvaten, Lowlipen, Prevencor, Stacor, Tarimyl, Torid, Torivas, Torvazin, Totalip, Trova, Tulip, Vastina

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Also known as: Atorvastatin

Description

Lipitor (atorvastatin) belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins."

Lipitor is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

Lipitor is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors such as genetically high cholesterol.

Lipitor is for use in adults and children who are at least 10 years old.

Dosage

Generic Lipitor can be taken in tablets. You should take it by mouth. It is better to take Generic Lipitor once a day at the same time with meals or without it. If you want to achieve most effective results do not stop taking Generic Lipitor suddenly.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Lipitor are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Lipitor if you are allergic to atorvastatin, or if you have:

liver disease; or if you are pregnant or breastfeeding.

Atorvastatin can harm an unborn baby or cause birth defects. Do not use if you are pregnant. Stop taking Lipitor and tell your doctor right away if you become pregnant. Use effective birth control to prevent pregnancy while you are taking this medicine.

Atorvastatin may pass into breast milk and could harm a nursing baby. Do not breastfeed while you are taking Lipitor.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

liver problems; muscle pain or weakness; kidney disease; diabetes; a thyroid disorder; or if you drink more than 2 alcoholic beverages daily.

Lipitor can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

Atorvastatin is not approved for use by anyone younger than 10 years old.

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For pH, sulphate, total hardness and aluminium, reduced sampling frequency had no discernible or systematic effect on the apparent annual mean chemistry relative to the values derived from weekly data. In vivo exacerbation of the phenotype by Kcnv2 transgenes supports its identification as an epilepsy modifier. These engineered vascular constructs, prepared from doxycycline-inducible inbred siPSCs, offer new opportunities for preclinical investigation of autologous human iPSC-based vascular tissues for patient treatment. The aim of this work was to develop a Spanish adaptation of the Revised Competitive State Anxiety Inventory-2. Both combination and polymorphism of Arg 16 will bring greater effect on the response to beta-2 agonist. This case of an unintentional ingestion of an unknown amount of potassium permanganate by a 5-year-old boy, and its sequelae, exemplifies the potential danger of this poison.

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We investigated the relationships between serum Lp(a) level and LDL particle size in coronary artery disease (CAD) patients. Impact of fenofibrate on NO and endothelial VCAM-1 expression in hyperlipidemic rats. There was a general lack of consistency between mRNA transcription and enzyme activities, indicating that these proteins and enzymes are not solely under transcriptional control. The research was designed as a randomized, double-blind, placebo-controlled, trial upon the volunteers registered from the outpatient department (OPD) with age ranging from 20 to 40 years. The level of plasma ET-1 was detected with radioimmunoassay, and the serum VEGF was measured by ELISA. Limited leaching has been observed in non-structured sandy soils, while subsurface leaching to drainage systems was observed in a structured soil with preferential flow in macropores, but only when high rainfall followed glyphosate application. Prematurely ended phase III trials in Sweden during the years 2002-2008. Endothelin-1 in the superior colliculus of rats induces depressor responses due to peripheral hemodynamic changes. Role of palliative chemotherapy in advanced epithelioid sarcoma.

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This collapse can be explained by a global glaciation (that is, a snowball Earth), which ended abruptly when subaerial volcanic outgassing raised atmospheric carbon dioxide to about 350 times the modern level. Effect of temperature on the cellular integrity of Bacillus psychrophilus. The Cardiac Infarction Injury Score as a predictor for long-term mortality in survivors of a myocardial infarction. Additional high mass accuracy analysis revealed 36 proteins whose extracellular abundance increased after treatment with phorbol ester (PMA), a protein kinase C agonist and general secretagogue. This matched a lack of environmental barrier dorsal and lateral to neural tube and the somites that is normally formed by PNA-binding proteins that block entry to medial pathways. Ipsilesional performance deficits are revealed in clinical tests of function that use time to completion as the measure of success. Program for mass vectorcardiographic studies with an electronic computer. Specific antibodies against structural proteins (actin, desmin, dystrophin, fibronectin) of muscle fibres were used to study the effect of forced lengthening contractions on muscle microarchitecture. An altered or less diverse gut microbiota composition has been associated with atopic diseases, obesity, or both. I conducted a wide review of medical and bio-psychosocial databases, coupled with a search of the grey literature.

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An evaluation of thermal dilution for obtaining serial measurements of cardiac output. Reversible contraceptive effect of the oviduct plug with nickel-titanium shape memory alloy and silicone rubber in rabbits. On the account of automatic registration of mDIBH CT images, manual registration was carried out based separately on the topside clip in the cavity, the labeled skin at anterior surface of the cavity at central level and the metal mark on the body surface near the cavity, then the displacements of center of the geometry in left-right (LR), anterior-posterior (AP) and superior-inferior (SI) directions based separately on the three registrations were measured. To investigate the expression and its clinical significance of Trop-2 in human pancreatic cancer. Using luciferase reporter assays, we also showed that MMP9 is a direct target of miRNA let-7e. We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE and EMBASE up to February 2013.

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Obese and overweight persons are at increased risk of heart failure. CRIF1 interacting with CDK2 regulates bone marrow microenvironment-induced G0/G1 arrest of leukemia cells. Referring patients with chronic noncancer pain to pain clinics: survey of Ontario family physicians. The heterogeneous nature of these vegetable-derived materials can lead to substantial lot- to-lot variability in cell culture processes. Malignant tumors and chronic infections in the masticator space: preliminary assessment with in vivo single-voxel 1H-MR spectroscopy. The effects of benzodiazepines on aggression: reduced or increased?. To investigate the status of source theolair drug information strength determination in terms of reference air kerma rate (RAKR) for HDR and PDR (192)Ir brachytherapy in Sweden. Discovering drug mode of action using reverse-engineered gene networks. Further, a comprehensive evaluation of results from various stimulation modalities may better clarify the pain mechanisms and gender/ethnic characteristics, as well as comparisons between normal subjects and patients.

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Plasma growth hormone (GH), insulin and amino acid responses to arginine with or without aspartic acid in pigs. Functional magnetic resonance imaging (fMRI) based on blood oxygen level-dependent (BOLD) contrast has become an increasingly popular technique for mapping the brain. Furthermore, enhanced EEG power in these frequency bands may respond to a neuromaturational delay as a result of excessive alcohol consumption during this critical brain developmental period. These results suggest a new target for regulation by syntaxin 1A and a novel mechanism for controlling the machinery involved in both neurotransmitter release and reuptake. Release of the plantar fascia and other ligaments was simulated to evaluate the corresponding biomechanical effects on load distribution of the bony and ligamentous structures. However, comparatively little is known about mixtures composed of chemicals from different classes of EDs.

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