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Fasigyn (Tinidazole)
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Fasigyn

Fasigyn is an antibiotic, which belongs to a group of medicines called nitroimidazoles. Fasigyn works by killing or stopping the growth of bacteria causing your infection. Fasigyn will not work against viral infections such as colds or flu.

Other names for this medication:
Simplotan, Tindamax, Tinidazole

Similar Products:
Sinequan, Theolair, Prandin, Imuran, Mobic, Glyburide, Lamisil, Cenforce, Azulfidine, Valium, Pidgrel, Orthocel, Cefpodoximum, Revenz, Biozin, Rexhist, Candiloss, Esomac, Anapril, Divalin,

Also known as: Tinidazole

Description

Fasigyn 500mg film-coated tablets contain 500mg of the active substance tinidazole. This medicine is an anti-infective agent. It is used to treat a variety of bacterial infections including: infections of the skin, blood, chest, lung, genitals or womb lining, an infection associated with stomach ulcers in combination with other drugs, infections caused by organisms called protozoa, such as amoebiasis and giardiasis (stomach infections) and trichomoniasis (a genital infection), vaginal infections (vaginitis) and gum infections (gingivitis).

It is also used before certain surgical operations to prevent bacterial infections developing.

You should ask your doctor if you are unsure why you have been given this medicine.

Dosage

Fasigyn tablets should be taken with plenty of water with or after meal. Swallow Fasigyn tablets whole, do not chew or crush. Fasigyn is not recommended for use in children less than 12 years. For urogenital Trichomoniasis: The recommended dose is 4 tablets (2 g) given as a single dose. For amoebic involvement of the liver (a liver infection): the recommended dose is 3 to 4 tablets (1,5 to 2 g) once a day for 3 to 6 days. For the infection associated with stomach ulcers: the recommended dose is 1 tablet (500 mg) taken twice a day. For most bacterial infections: the recommended dose is 4 tablets (2 g) on the first day then 2 tablets (1 g) once a day or 1 tablet (500 mg) twice a day. The usual length of treatment is 5 to 6 days. For bacterial vaginitis (a vaginal infection) and acute ulcerative gingivitis (a gum infection): the recommended dose is 4 tablets (2 g) given as a single dose. For vaginitis you may be given 4 tablets (2 g) on two consecutive days. For protozoal infections (intestinal amoebiasis): the recommended dose is 4 tablets (2 g) once a day for 2 to 3 days. Prevention of postoperative infections in adults (over 12 years): the recommended oral dose of 2 g approximately 12 hours before surgery.

Overdose

If you take too much of this medicine tell your doctor or contact your nearest hospital casualty department immediately. Take any remaining tablets with you.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Fasigyn are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Pregnancy: Fertility studies in rats receiving 100mg and 300mg tinidazole/kg had no effect on fertility, adult and pup weights, gestation, viability or lactation. There was a slight, not significant, increase in resorption rate at the 300mg/kg dose. Tinidazole crosses the placental barrier. Since the effects of compounds of this class on foetal development are unknown, the use of tinidazole during the first trimester is contraindicated. There is no evidence that Fasigyn is harmful during the latter stages of pregnancy, but its use during the second and third trimesters requires that the potential benefits be weighed against possible hazards to mother or foetus.

Breast-feeding: Tinidazole is excreted in breast milk. Tinidazole may continue to appear in breast milk for more than 72 hours after administration. Women should not nurse until at least 3 days after having discontinued taking Fasigyn.

No special precautions should be necessary. However, drugs of similar chemical structure, including Fasigyn, have been associated with various neurological disturbances such as dizziness, vertigo, ataxia, peripheral neuropathy (paraesthesia, sensory disturbances, hypoaesthesia) and rarely convulsions. If any abnormal neurological signs develop during Fasigyn therapy, the drug should be discontinued.

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We have developed a range of group-specific PCR primers for studying the prey diversity found in predator stomach contents and scats. A rapid diagnostic overview is obtained with HaeIII and HinfI digestion of the ITS region. It is concluded that SCH27899 itself contributes, at least in part, to a uricosuric effect following i.v. Measures of positive mental health states are needed for population-based research. The phoS mutants showed only a two- to threefold reduction when grown with organic phosphate sources. Deviation from published guidelines in the management of primary spontaneous pneumothorax in Australia. This article describes the use of Q-methodology and presents the results of a Q-study on perspectives on disability carried out in a training workshop as evidence for its usefulness in disability research. These mainly relate to grossly inadequate capacity to deal with multidimensional patient needs, allowing progression to chronic pain states and much higher health care costs. Saudi Arabia therefore appears to be a non-endemic area for HTLV-I and hence the current practice of screening all blood donors for anti-HTLV-I does not seem to be cost-effective.

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To determine the triggers of blood transfusion in patients undergoing percutaneous nephrolithotomy (PCNL). The prevention and promotion program in public oral health was effective in preventing caries disease, gingivitis, and malocclusion in children under 5 years of age. Softening of thermoplastic polyurethanes: a structure/property study. In this manner, cells were exposed to both the vapor and particulate phase of smoke efficiently. No significant differences in skill acquisition were attributable to amount of sleep. Deferrals for low hematocrit were significantly higher for both sexes at and above 45 degrees F. Random phage display library is used to map conformational as well as linear epitopes. Consistent with studies in other organs, instillation of an endothelial stimulant (interleukin-1) was PECAM-1-dependent.

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More recently, we have shown that Fc epsilon RI, the high affinity IgE receptor thought to be only expressed by basophils and most cells, was involved in eosinophil-mediated cytotoxicity against schistosomes as well as in mediator release. The Role of Xanthine Oxidase Inhibitors in Patients with History of Stroke: A Systematic Review. Leads were implanted bilaterally into the internal part of the globus pallidus under stereotactic guidance. Hormonal control of the expression of antibody-defined lactosaminoglycans in the mouse uterus. Direct writing of bio-functional coatings for cardiovascular applications. Contribution of high-resolution correlative imaging techniques in the study of the liver sieve in three-dimensions. In one case, the duplicated IVCs were both located to the right of the abdominal aorta and were nearly on the same coronal plane. Ethical Design of Intelligent Assistive Technologies for Dementia: A Descriptive Review. A mouse model to study hypersensitivity responses to salt-soluble wheat protein (SSWP) extract is currently unavailable.

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CT staging is considered accurate in one-half to two-thirds of patients, but limitations in the imaging of peripancreatic microinvasion and nodal or hepatic micrometastases still have a tendency to underestimate tumor extension. We now show that deoxycholate promotes the stable recruitment of IpaB to the needle tip without inducing a rapid burst of type III secretion. The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signals. The human prostate-specific transglutaminase gene (TGM4): genomic organization, tissue-specific expression, and promoter characterization. Here we show that AAV vectors can efficiently target the PRNP gene encoding the prion protein PrP in bovine fetal fibroblasts, which can be used as nuclear donors to clone cattle. At 10 years, stentless valve durability is excellent and comparable with that of stented valves. In the sheep undergoing conventional thoracotomy, the physiological conductivity of intercostal nerve was completely blocked immediately after retractor placement using the same stimulation intensity or even the supra-threshold intensity. A simplified model of mammography geometry for breast cancer imaging with electrical impedance tomography. Spatial patterns concentrations in upland Wales in relation to catchment forest cover and forest age. Macrophages in cerebrospinal fluid are described as indicators of pathology.

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Improving health insurance coverage for Latino children: a review of barriers, challenges and State strategies. Ultrastructural demonstration of thioredoxin and thioredoxin reductase in rat hepatocytes. No significant gross abnormalities were observed at postmortem examination, while histopathological analysis revealed diffuse necrotizing enterocolitis. Dissection of a renal artery is rare and, in most cases, associated with underlying arterial diseases. Our data, therefore, suggest that root canal sealers may be an effective inhibitor of LPS-induced inflammatory effects in macrophage cells. Reduced Bax expression and enhanced Bcl-2 expression by Id-1 were also noted in the presence of taxol. Despite the profound defect of the innate immune response, MyD88 deficiency allows the emergence of an adaptive immunity.

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This has implications to greatly improve the feasibility of implementing simulation-based curricula in residency training programs, rather then having them being limited to research protocols. Specialized finite element methods are used for simulating three dimensional electrical propagation and mechanics. Effects of HCO3- on cell composition of rabbit ciliary epithelium: a new model for aqueous humor secretion. However, no significant difference in the improvement of nutrition knowledge levels was observed with the second intervention over the first intervention as already the children in the experimental group gained knowledge through print media. We describe the identification of MEN15658, a molecule characterized by a promising cytotoxic effect against human tumor cell lines, including platinum- and anthracycline-resistant ovarian carcinoma.

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The level-dose ratio in both groups varied only moderately indicating absence of major exogenous influences. Admissible studies were screened using explicit threshold criteria and appraised for methodologic rigor against criteria promulgated by the Agency for Healthcare Research and Quality. Pre-transplantation serum albumin, a clear predictor, the number of blood units transfused and re-transplantation are all independent predictors of IFI. Each reader also was consistent with himself on duplicate readings of 21 photographs (ICC, 0.80-0.88 for rim area and 0.95-0.98 for all other measurements), but reproducibility was not as good as SD OCT. The mechanisms by which NK cells recognize target cells in an antigen-specific manner are largely unclear. The BVD-virus-infection is at present the economically most important disease of bovine animals. Of the participants, 38 were diagnosed as having restless legs syndrome. Vitamin D supplementation has a role in reducing treatment-related toxicities, especially in advanced cancer. First sign of efficacy was less frequently reported at the early dose-levels and MTD was less frequently reached in trials investigating molecular targeted therapy alone. Relationship between adenoids hypertrophy and secretory otitis media.

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In one co-culture model the EC were cultured on the SMC, whereas in the other model the EC and SMC were cultured on the opposite sides of a membrane. Hereditary spherocytosis - development peculiarities in 9 families. This approach is shown to be a powerful tool for identifying genes encoding novel proteins with specific sub-nuclear localisations and exposes our ignorance of the protein composition of the nucleus. CT and MR are the imaging techniques of choice for the primary diagnosis and the follow up of these tumors. The component(s) in blood that initiates these changes is(are) not known, although iron is often proposed as one possibility. Given the concern that mortality rates may be increased in geriatric patients exposed to atypical antipsychotic agents, we assessed mortality rates for adult patients with schizophrenia assigned to an investigational antipsychotic (olanzapine, quetiapine, risperidone, or ziprasidone), a control antipsychotic (haloperidol or chlorpromazine), or placebo in preapproval clinical development programs to assess relative risk with atypical antipsychotics as compared to typical antipsychotics or placebo.

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This method allows the creation of addressable QD arrays on macroscopic glass surfaces. FA patients are at high risk of squamous cell tumors, and gynecologic examinations should begin at menarche. We further characterized spatial variability in the risk within the cabin by modeling a previously reported TB outbreak in an airplane to demonstrate that the TB cases occur most likely within close proximity of the source TB patient. Based on this observation, we developed a genetic screen to identify domains in Vam3p (e.g., localization and/or specific protein-protein interaction domains) that allow it to efficiently substitute for Pep12p. Upon binding of antibodies, these proteins are quickly internalised through a new clathrin- and caveolae-independent internalisation pathway. Visible Chinese Human datasets are so massive in size they require the use of parallel computing resources for effective visualization. CD2-associated protein is widely expressed and differentially regulated during embryonic development.

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Rather, measurements from this group were much like those for dark-reared control mice. After whole genome amplification (WGA) based on multiple displacement amplication (MDA) for a single cell, we did regular PCR following sequencing and detected the genotypes using the real time PCR based on TaqMan probes. Abnormal Doppler velocimetry of the ductus venosus was the only significant parameter associated with perinatal death and low 5-min Apgar scores. The fixator comprises an adjustable single outrigger bearing offset pins which offers considerable versatility in its use. To assess safety and efficacy of a murine anti-CD4 monoclonal antibody (Mab) in a population of patients with rheumatoid arthritis (RA) compared to treatment with placebo. Effect of early versus late in-hospital initiation of statin therapy on the clinical outcomes of patients with acute coronary syndrome. We were able to observe some interesting trends such as potential discordance with ECOG score and assessment of Fit/Vulnerable/Frail but due to limitations in the data, this paper is not able how fast does diflucan 150 mg work to illustrate definitive correlations.

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A total of 444 cases with at least one of the microvascular complications of T2D and 439 age- and gender-matched controls free of any of the chronic microvascular complications of T2D were included. Importantly, restriction was not mediated through effects on translation efficiency since replicons with high CpG/UpA sequences inserted into a non-coding region were similarly replication defective. A force feedback algorithm for cranial implant design is presented in this paper. 17alpha-ethinylestradiol cometabolism by bacteria degrading estrone, 17beta-estradiol and estriol. Amitriptyline was found to be nongenotoxic at plasma levels by all the parameters assayed.

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Normalized vessels do not induce tumor hypoxia, and may protect from cancer cell intravasation and enhance anticancer treatment with chemotherapeutic agents, radiation, or immune therapy. We developed a stable sensitive ELISA for detection and determination of pro-hepcidin in human serum. EPA Endocrine Disruptor Screening Program (EDSP) Tier 1 in vitro assays. Development of very large electrode arrays for epiretinal stimulation (VLARS). We hypothesized that cigarette smoke directly up-regulates expression of apoptotic genes, which could play a role in airway epithelial apoptosis. We conclude that the direct binding of inhibitors to nucleic acids mask their TLR-binding epitope and may explain the efficiency of those compounds in the treatment of autoimmune diseases. The first phase is a local modeling of the peak displacement between two consecutive experiments using distance matrices. We demonstrate that quinolone binding and drug-induced DNA cleavage are separate processes constituting two sequential steps in the mechanism of action of quinolones on DNA gyrase. In vivo and in vitro assays reveal a direct interaction between pRb and the AhR but not the AhR nuclear translocator protein. Some grains appeared with time over pale granular materials that appeared in the intercellular spaces of secretory ameloblasts with colchicine treatment.

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This pilot study demonstrates that septal injection of BTA in patients with IR can achieve good symptom control and patient comfort and should be compared in further studies to the conventional turbinal injection technique. It is a primary attempt to evaluate the distribution of inner body temperature noninvasively by means of thermographs and provides a new way to analyze bio-heat transfer. In contrast, the weight measurements were on average below the mean until age 2 years. This article reports the case of a 24-year-old female who suffered a gunshot wound to the abdomen and subsequently developed a superior mesenteric artery (SMA) pseudoaneurysm and APF, which caused secondary right heart failure and pulmonary hypertension. Crystalline-matrix urethral plugs have not been previously reported in dogs. Results showed that the fractional Kelvin-Voigt model best fitted the experimental data obtained from creep and frequency sweep tests. Plant productivity was significantly greater in genotypic polycultures compared to what was expected based on monocultures. However, the role of NGF in relation to its high-affinity trkA receptor in the cortical neurons has not been well discussed. As a consequence, a consistent deviation from CA could be obtained in three of four herbicide mixtures for L.

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