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Eldepryl (Selegiline)
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Eldepryl

Eldepryl is a monoamine oxidase type B (MAO-B) inhibitor prescribed for the management of the symptoms of Parkinson's disease in patients already taking levodopa-carbidopa.

Other names for this medication:
Elegelin, Emsam, Jumax, Jumex, Selegiline, Selerin, Selgin, Zelapar

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Also known as: Selegiline

Description

Eldepryl (selegiline) prevents the breakdown of a chemical in your brain called dopamine. Low levels of dopamine are associated with Parkinson's disease.

Eldepryl capsules are used together with levodopa and carbidopa to treat symptoms of Parkinson's disease.

Dosage

Take Eldepryl orally. Take Eldepryl capsules twice a day, at breakfast and lunch. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. Do not drink or eat anything for at least 5 minutes after takink Eldepryl. While using Eldepryl, you must not eat foods that are high in tyramine such as air dried meats, aged or fermented meats, sausage or salami (including cacciatore and mortadella), pickled herring, and any spoiled or improperly stored beef, poultry, fish, or liver; beer from a tap, beer that has not been pasteurized; aged cheeses, including blue, boursault, brick, brie, camembert, cheddar, emmenthaler, gruyere, parmesan, romano, roquefort, stilton, and swiss; sauerkraut, soy beans, soy sauce, tofu, miso soup, bean curd, fava beans; yeast extracts (such as Marmite). Preferable food during Eldepryl usage are fresh meat, poultry, or fish (including lunch meat, hot dogs, breakfast sausage, and cooked sliced ham); any vegetables except broad bean pods (fava beans); processed cheese, mozzarella, ricotta, cottage cheese; pizza made with cheeses low in tyramine; soy milk, yogurt. If you want to achieve most effective results do not stop taking Eldepryl suddenly.

Overdose

If you overdose Eldepryl and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Eldepryl overdosage: severe headache, hallucinations, vision problems, sweating, cool or clammy skin, fast or uneven heart rate, feeling light-headed, fainting, seizure.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Eldepryl dosage information

Side effects

The most common side effects associated with Eldepryl are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Eldepryl if you are allergic to selegiline, or if you have taken fluoxetine (Prozac, Sarafem and others) within the past 5 weeks.

Some medicines can cause unwanted or dangerous effects when used with Eldepryl. Your doctor may need to change your treatment plan if you use any of the following drugs:

cough medicine that contains dextromethorphan; cyclobenzaprine (Flexeril); meperidine (Demerol) or other narcotic (opioid) pain medicine; methadone; St. John's wort; tramadol (Ultram, Ultracet); an antidepressant - citalopram, desvenlafaxine, duloxetine, escitalopram, fluvoxamine, levomilnacipran, milnacipran, mirtazapine, nefazodone, paroxetine, venlafaxine, vilazodone, vortioxetine, and others; or p>an MAO inhibitor - isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

After you stop taking Eldepryl, you must wait at least 14 days before taking any of the medications listed above.

To make sure Eldepryl is safe for you, tell your doctor if you have:

liver or kidney disease; high blood pressure; or

People with Parkinson's disease may have a higher risk of skin cancer (melanoma). Talk to your doctor about this risk and what skin symptoms to watch for.

It is not known whether Eldepryl will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether selegiline passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

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