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Depakote (Divalproex)

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Depakote is a first-choice medication to treat certain seizures, mania caused by bipolar disorder, and prevent migraines. The medication has many possible side effects and can sometimes damage the liver.

Other names for this medication:
Biproate, Dilex, Diproex, Disorate, Divaa, Divalex, Divalprid, Divalpro, Divalproex, Dixval, Drvel, Encorate, Epival, Epsoval, Jydival, Kayval, Napilex, Nepilex, Sezex, Spikalon, Valate, Valcot, Valep, Valfox, Valimep, Valowin, Valparin, Valpex, Valporil, Valporl, Valprid, Valprol, Valtaril, Valtec, Velpo, Velze, Vinchorate

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Also known as: Divalproex


Depakote is a perfect remedy in struggle against seizure disorders. Depakote acts by increasing the amount of a certain natural substance in the brain. Depakote is also known as Valproate semisodium, Divalproex sodium, Valproic acid, Divaa. It is anticonvulsant. Generic name of Depakote is Divalproex Sodium. Brand names of Depakote are Depakote, Depakote ER, Depakote Sprinkles.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Drink plenty of water while you are taking this medication. Your dose may need to be changed if you do not get enough fluids each day.

Swallow the capsule or tablet whole and do not crush, chew, break, or open it.

If you cannot swallow a sprinkle capsule whole, open it and sprinkle the medicine into a spoonful of pudding or applesauce. Swallow the mixture right away. Do not save it for later use.

You may need frequent blood tests.

If you need surgery, tell the surgeon ahead of time that you are using Depakote Sprinkles.

In case of emergency, wear or carry medical identification to let others know you use Depakote Sprinkles.

Do not stop using Depakote Sprinkles suddenly, even if you feel fine. Stopping suddenly may cause a serious, life-threatening type of seizure. Follow your doctor's instructions about tapering your dose.

Store at room temperature away from moisture and heat.

Detailed Depakote Sprinkles dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Valproic acid dosage information

Side effects

The most common side effects associated with Depakote are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of valproic acid in the elderly. However, elderly patients are more likely to have unwanted effects (eg, tremors or unusual drowsiness), which may require an adjustment in the dose for patients receiving valproic acid.

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Horizontal changes of the proximal mandibular segment after mandibular setback surgery using 3-dimensional computed tomography data. Progressive infarction, identified by myocyte sarcomere disruption and subsequent cell loss, occurs in parallel with fibroblast invasion and gap junction remodeling. Predominant serovars of Salmonella in humans and foods from Thailand. A neuro-immune, neuro-oxidative and neuro-nitrosative model of prenatal and postpartum depression. Vinblastine, an anticancer drug, causes constipation and oxidative stress as well as others disruptions in intestinal tract in rat. Initially, this patient underwent off pump coronary revascularization. Most of the results from epidemiologic studies support the general idea that high density lipoproteins (HDL) cholesterol is inversely related to coronary heart disease (CHD) incidence. The frequencies of micronuclei (MN) and sister-chromatid exchanges (SCEs) were measured in peripheral blood lymphocytes from the two groups of volunteers.

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