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Danocrine (Danazol)
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Danocrine

Danocrine treats endometriosis (a painful condition involving the tissue of your uterus), but it's not a first-choice medication because of the side effects. Depending on how severe the condition is, the dose can range from 200 mg to 800 mg by mouth per day, in two divided doses. The medication is usually used for 3 to 6 months.

Other names for this medication:
Benzol, Danazol, Danogen, Danozec, Dazol, Donogen, Endometryl, Endozol, Gonablok, Gynadom, Gynazol, Gynodan, Gynol, Ladogal, Pozol, Zendol

Similar Products:
Vermox, Motilium, Altace, Bactrim, Klonopin, Coreg, Eulexin, Xalatan, Imovane, Tetralisal, Duloxetine, Laogine, Etophylline, Czartan, Nidcyclin, Doloage, Serxanti, Xenobid, Oncotam,

Also known as: Danazol

Description

Danocrine is used to treat endometriosis.

Danocrine is also used to treat attacks of hereditary angioedema (an immune system disorder).

Dosage

Take Generic Danocrine by mouth with a glass of water. Take this medicine with food to decrease stomach upset. Take your doses at regular intervals. Do not take your medicine more often than directed. If you want to achieve most effective results do not stop taking Generic Danocrine suddenly. Women who take danazol may need to start the medication during a menstrual period. Follow your doctor's instructions.

Overdose

If you overdose Generic Danocrine and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at a room temperature between 4 and 30 degrees C (39 and 86 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Danocrine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Danocrine if you are allergic to it, or if you have:

undiagnosed vaginal bleeding; severe heart problems; a history of stroke or blood clot; severe liver or kidney disease; porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system); or a history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina.

Tell your doctor if you have ever had:

heart problems; high blood pressure; liver disease; kidney disease; epilepsy or other seizure disorder; diabetes; or migraine headaches.

You may need to have a negative pregnancy test before starting this treatment.

Do not use Danocrine if you are pregnant. It could harm the unborn baby or cause birth defects. Use effective birth control to prevent pregnancy while you are using this medicine.

Ask your doctor about using a non-hormonal birth control (such as a condom or diaphragm with spermicide) to prevent pregnancy.

Danazol can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using danazol.

Danocrine is not approved for use by anyone younger than 18 years old.

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Simultaneous effects of various environmental factors on man--literature review on the situation in the plastics industry. The minimum detectable limits of the NO(2) instrument developed have been estimated to be 0.14 ppbv and 0.39 ppbv (parts per billion, 10(-9), by volume) in 60 s integration time (signal-to-noise ratio of 2) for 473 and 410 nm excitation systems, respectively. Three fMRI activation paradigms were used: contralateral to the lesion: ballistic opposition of the fingers, flexion-extension of the foot and click of the tongue. Surgical Implications for Diagnosis and Treatment of Intestinal Aspergillosis in Pediatric Patients with ALL. Hyperchromasia and an Orange G (OG)-philic cytoplasm of squamous cells were frequently observed in the moderate compared with the mild dysplasias. GSK3 activity was decreased in mouse embryonic fibroblasts (MEFs) genetically and pharmacologically, and changes in the cyclical expression of core clock genes--mPer2 in particular--were examined. Such model involves a minimal number of known biochemical mechanisms: it basically relies on the interplay between cell division and cell death inhibitors on one hand, and membrane receptors on the other. Inhibition of influenza virus and interferon response intranasally with statolon. The ultimate aim is to apply it in catalytic activity and electronic devices.

danocrine generic name

Bicyclonucleosides bearing a 5-deoxy-5-N-hydroxyamino-3,N5-(1,1-ethano)-beta-D-furanosyl sugar moiety (15-18) have been prepared by glycosidation of the corresponding bicyclosugars obtained via an intramolecular reverse Cope elimination. The presence of multiple diffusion-weighted imaging lesions of varying ages suggests very active early recurrence over time and portends a higher early risk of future ischemic events. Gel chromatography in denaturing solvents: a method for the study of protein subunit composition. Agreement between clinician and reading center gradings of diabetic retinopathy severity level at baseline in a phase 2 study of intravitreal bevacizumab for diabetic macular edema. Ventilator associated pneumonia (VAP) is a major cause of poor outcome among patients in the intensive care units (ICU) world-wide. 48- to 72-hour canine kidney preservation by means of hypothermic non-pulsatile perfusion. SVM algorithms may be used to stratify idiopathic cases of ASD according to behavioral signature patterns associated with genetic disorders. Collectively, our results indicate that HIP1-ALK-positive NSCLC may benefit from clinical applications of crizotinib.

danocrine

Among schizophrenic patients, source misattribution of self-generated items was significantly correlated to an executive, planning performance. In the present investigation we have used human procathepsin D and a synthetic 44 amino acid peptide corresponding to the activation peptide of procathepsin D to test its growth factor activity for human prostate cancer-derived cell lines PC3, DU145 and LNCaP. Complementary alternative medicine use is common in women with chronic vaginitis, particularly in those who are young, have more disruptive symptoms, and report greater stress. Relaxin has been reported to reduce fibrosis in the kidney, heart, lung, and liver and to promote wound healing. Recognizing the dearth of qualitative research on hepatitis C virus (HCV) infection associated with injecting drug use in the UK, this paper summarizes qualitative insights from a study exploring the social relations of HCV risk management among drug injectors in London. The maximum population EVPI was CHF 6.8 million in overweight people and CHF 3.2 million in moderate obese people, representing the upper limit on costs associated with decision uncertainty. Although the cellular source and role of these immune ligands are better known, their exact contribution to brain protection, repair or diseases still remains highly debated today. Our laboratory previously showed that the CSVTCG (cys-ser-val-thr-cys-gly) sequence of TSP-1 functioned as a tumor cell adhesion domain and CSVTCG peptides as well as an anti-peptide antibody possessed anti-metastatic activity in a murine model of lung metastasis. Twelve live births resulted but a Downs syndrome baby died in the perinatal period.

danocrine

Crystal structure and DFT study of 2-(pyren-1-yl)-1H-benzimidazole. As demonstrated here for a number of genes, this homology based approach can be used successfully for predicting partial gene structures. Mutations in this gene lead to the Finnish-type congenital nephrotic syndrome. In adults, both transcripts were present in a wide variety of tissues, including some not previously known to express myostatin. These guidelines allowed substantial sparing of the contralateral parotid gland. Considering the substantial addictive potential of online-gambling and hints of a future trend away from offline- towards online-gambling, preventive measures like public restrictions for online providers and awareness campaigns for consumers about the dangers of online-gambling offers are reasonable. Mathematical modeling of the cardiac action potential has proven to be a powerful tool for illuminating various aspects of cardiac function, including cardiac arrhythmias. Appraisals of the response as illegitimate mediated the effects of victim group response (Studies 3 and 4). In order to answer these questions we ordered the genes of the published Wnt target screenings according to their functions, and summarized the pathways, which are regulated by the Wnt pathway.

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The results suggest that when prior fractionation is carried out to enrich for cell organelles, subcellular components of cells, or cell membranes, it is routinely possible to obtain numerous N-terminal sequences from one or a few 2DE gels of such fractions. toxic action, cytostatic action and induction of chromosomal aberrations are discussed. Because of the size, nano-pharmaceutics show some special characteristics of pharmacokinetics (PK). Interaural level differences (ILDs) can therefore affect the ITD cue. SA reduced electrolyte leakage, indicating that it induced membrane thermoprotection. The genetic differences in control elements of MHC class II genes may well contribute to differential immune reactivities and to immune disorders like allergies or autoimmune diseases. In this study, we examined whether the human lateral and medial parietal lobes have differential anatomical and functional connectivity with the temporal lobe. Retrospective analyses suggest that 1 month of anticoagulation is adequate for patients whose venous thromboembolic event was provoked by a transient risk factor. Idiopathic hypercalciuria (IH) in adults is recognized as a cause of urolithiasis. The IL-5 and IL-8 release by the SAL or SEP-stimulated resident cells may act in an autocrine fashion, thus potentiating LTB4 release.

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Efficacy of mechanical insufflation-exsufflation in medically stable patients with amyotrophic lateral sclerosis. The current manuscript addresses this gap in the empirical literature by examining the feasibility and acceptability of OMT-based parent-adolescent sexual health interventions for African American and Latino families. Because kinetic studies of mutants show that the redox gating of protons occurs deep within the D channel close to the heme-copper site, the present study implies that no motion is transmitted to the ends of the helices. Hydrolysis of urinary metabolites of different steroid hormones by -glucuronidase from Escherichia coli. The circular symmetry is broken because of the hydrodynamic instability at the tip of the underlying gravity current. Of 133 drug-related research grant proposals, 74 were included for complete data extraction. However, there are no data on the rate of congenital transmission of T. The enzyme contains a peptidase domain with an alpha/beta hydrolase fold, and its catalytic triad (Ser554, His680, Asp641) is covered by the central tunnel of an unusual beta propeller. Chlorophyll fluorescence imaging was performed under light treatment, showing a greater decrease of photochemical efficiency in red and light green patches than in green sections.

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We will review how recent advances in developmental and stem cell biology have made it possible to generate complex, three-dimensional, human intestinal tissues in vitro through directed differentiation of human pluripotent stem cells. Re: Testicular spermatozoa have statistically significantly lower DNA damage compared with ejaculated spermatozoa in patients with unsuccessful oral antioxidant treatment. This is contrary to our intuition that the fluctuations are weaker at a lower temperature. The gastropods showed about 20-fold higher concentrations than the bivalves. Examination of human rectal, uterine, bladder, colon, small intestine, arterial, and venous smooth muscle by immunohistochemical techniques shows that each of these tissues is immunopositive for both smooth muscle myosin and human Mb. We present a review of vwMRI research in relation to intracranial atherosclerosis, with a focus on the relationship between ischemic stroke and atherosclerotic plaque T1 post-contrast enhancement or plaque/vessel wall morphology. It was preceded by passage of a large, bulky stool, containing numerous undigested, fluid-filled raisins. Our finding indicated that the AgNPs was less active than GR but it had anti-dermatophytic effect.

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Many physicians decide to acquire a Master of Business Administration degree to understand the business of medicine. flexneri 2b, that had evidently been frequent in central Europe 40 years ago, disappeared completely. The results show that the operations do not qualitatively change the subcellular localization of AChRs, but they do alter the levels relative to control ganglia. The system is developed in order to improve on existing video playback approaches as used in multimedia applications by providing control over not only time, as in conventional video playback, but also space. Cardiac arrest (CA) was induced in Sprague-Dawley rats with an IV bolus of KCl (40 microg/g). Cathepsin D (CD) is an essential lysosomal protease and mice lacking this enzyme exhibit neuropathology similar to that observed in brains of patients with neuronal ceroid lipofuscinosces (NCL/Batten disease), a group of autosomal recessive pediatric neurodegenerative diseases.

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3D motion analysis of foot kinematics was performed in eight patients with hallux rigidus and 11 healthy control participants with a 12-camera system, using the Heidelberg foot measurement method before and one year after surgery. The study used a twin-based design and a new theoretical model, the causal-common-contingent (CCC) model. Randomised controlled trials reported in languages other than English are generally excluded from systematic reviews. ClinOleic may offer significant advantage over soybean oil-based emulsions in terms of glucose metabolism in preterm infants. Accuracy and efficiency of the proposed algorithm and its distributed equivalent are investigated by using several test models.

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Experiment 1 found blink magnitude inhibition in a visual tracking task. NHA showed less proliferative and more cytotoxic effect than other tested materials. In summary, our results confirmed that the insertion of TOAC-probe in the N-terminal region of peptides does not significantly modify the affinity or biological activity in vitro and in vivo conditions and could be an important tool to evaluate peptide-receptor interaction mechanism. Unfortunately, despite 50 years of intense study, many gaps remain in the scientific understanding of liver regeneration. Phantom and animal studies have convincingly shown how SPECT AC recovers the true regional myocardial activity concentration, while non-AC SPECT does not.

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danazol drug class 2021-01-12

Effect of platelet-rich plasma on the proliferation and adipogenic differentiation of human adipose-derived stem cells in vitro. Whites (WHs) (694 males and 929 females) and African-Americans (AAs) (92 males and 167 females) at risk for radiographic KOA were eligible. Here we show using both simulations and mathematical analysis that not only the rate but the phase of the postsynaptic response to a rhythmic population input varies as a function of synaptic dynamics and synaptic configuration. Nosocomial, also known as hospital acquired infections, are today considered to be an important indicator of the quality of health care in all health establishments. Chaotic Synchronization of Multi-neurons in External Electrical Stimulation. In the hypothalamus, insulin and leptin share a common signaling pathway involved in food intake, namely the insulin receptor substrate, phosphatidylinositol 3-kinase pathway. Perceived autonomy, overall job satisfaction, and specific work incentives and disincentives were surveyed in 249 occupational therapists.

danocrine medicine 2016-06-18

In the absence of PARP-1, NF-kappaB activation and induction kappaB-target genes did not take place during the promotion of tumor development. K restriction inhibits protein phosphatase 2B (PP2B) and suppression of PP2B decreases ROMK channel activity in the CCD. There were, however, significant differences in 3 schemas of ethical reasoning based on the new Defining Issues Test (DIT2). Photo induced hexylaminolevulinate destruction of rat bladder cells AY-27. Microtubule-associated protein 1B, MAP1B, is one of the major growth associated and cytoskeletal proteins in neuronal and glial cells. Data analysis used three major themes: language, understanding and sources of knowledge. Average numbers of necklace strands in secondary olfactory cilia increase from 3-4 at the 16th and 17th gestational days to 6-7 in adults. To measure relative employer-sponsored postablation costs for cardiac arrhythmias (CA), specifically atrial fibrillation (AF).

danazol dosage 2016-05-21

The FASRAT will enable residential aged care facilities to measure the attitudinal beliefs of its staff about staff-family relationships and provide a basis for the development and implementation of interventions to address identified gaps which impact on relationship quality. Treatment with Sulforaphane Produces Antinociception and Improves Morphine Effects during Inflammatory Pain in Mice. Obesity and screening PSA levels among men undergoing an annual physical exam. Measurements of mAChR-associated second messengers indicated no significant differences between normal and diabetic rat atria in the stimulatory effect of carbachol on protein kinase C activity and the production of inositol phosphates, or in the inhibitory effect induced by carbachol on cyclic AMP (cAMP) production. The elimination phase of the curves did not differ among the treatments as a result of administration of the prokinetic agents. GPI membrane anchors of cell surface glycoproteins have been shown to confer functional properties that are different from their transmembrane (TM)-anchored counterparts. aureus can also gain entry into the host and cause life-threatening infections or persist as disease foci that develop into suppurative abscesses. To evaluate the use of proton pump inhibitors and histamine H2 receptor antagonists in pediatric gastroesophageal reflux disease through a systematic review.

danocrine 2015-07-12

The majority of the tested materials harbored bacteria in their samples before and after clinical storage. We expressed dCAT-1 or mCAT-1 of NIH 3T3 origin in cells that are not normally infectible with ecotropic MLVs and evaluated the transfectants for susceptibility to virus infection and to virus-induced syncytium formation. One patient with severe motor deficits was also studied at 4 what is the drug minocin used to treat months when her motor deficits improved up to MRC grade 4. A rare case of talar body fracture combined with traumatic rupture of the anterior talofibular ligament and peroneal longus tendon is presented and reports in the literature are reviewed. Different tissue biochemistry in patients with concomitant detrusor instability. These data provide the first evidence that the Rad51 protein can be modified so as to increase the frequency of gene repair in yeast. The main outcome measure was to determine whether hypermethylation of the genes for either transporter is associated with loss of their expression and with a positive (99m)Tc-sestamibi scan. Alpha-L-fucosidase activity in patients with ductal cholelithiasis. Identification and quantitation of usnic acid from the lichen Usnea species of Anatolia and antimicrobial activity.

danocrine cost 2021-04-06

A mechanism for the formation of the ionic products observed in negative surface ionization thermal electron attachment to SF6 is presented. After a call-based data reduction step to filter out non class-discriminative probe sets, the gene list obtained was reduced to a predictor with correction for multiple testing by iterative deletion of probe sets that sequentially improve inter-class comparisons and their significance. Four fistulated Holstein cows were arranged in a 4 x 4 Latin square design to study the effects of level and type of energy source on milk yield and composition. (1998) Structure 6, 23-32) of human deoxyhypusine synthase revealed four active sites of the homotetrameric enzyme located within deep tunnels. The factors shown to be associated with fatigue in this study will be helpful in shaping future studies. Under extinction conditions, METH-priming or re-exposure to cues previously paired with METH infusion markedly increased the responses (reinstatement of drug-seeking). (brahmi) is known as a medicinal plant used for memory enhancement. For valine-derived copolymers, the coil-globule transition is basically unmodified with respect to pNIPAAm, whereas doping with leucine-derived groups significantly lowers the transition temperature and makes the transition discontinuous. This study compared the efficacy of a cinacalcet-based regimen with unrestricted conventional care (vitamin D and phosphate binders) for achieving the stringent National Kidney Foundation Kidney Disease Outcomes Quality Initiative (KDOQI) targets for dialysis patients.

danocrine cost 2015-03-18

These results suggest that the increase in IFs in hepatocytes results from the adaptation of the hepatocytes to the stress imposed by bile duct ligation. In this preclinical study, the toxicity profiles of B43-Genistein as well as unconjugated genistein were evaluated in mice. The study included 100 infertile women, aged 21 to 41 years, who underwent surgical treatment of endometriosis. Results demonstrate that nondestructive testing with unilateral NMR is a potential method for use in the quality control of implants and for the screening of implants for rupture after implantation. At baseline, hypertensive rats had a significantly higher arterial blood pressure than normotensive rats, while intraocular and intracerebroventricular pressures and TPG did not differ between the groups.

danocrine dosage 2020-03-20

Partial characterization of phosphoribosyl transferase, phosphoribosyl anthranilate isomerase, and indole glycerol phosphate synthase from Serratia marcescens. Speckle-tracking echocardiography for predicting outcome in chronic aortic regurgitation during conservative management and after surgery. Nuclear erythroid-related factor 2 (Nrf2), a redox-sensitive transcription factor, is involved in transcriptional regulation of many antioxidant genes, including glutamate-cysteine ligase (GCL). The vector was transferred into callus cells from wheat (Triticum aestivum L.) immature embryos by particle bombardment. BRCA1-IRIS alone or in complex with steroid receptor co-activators was targeted to the cyclin D1 promoter pre-bound by the c-Jun/AP1 and activated its transcription, which could explain the co-overexpression of BRCA1-IRIS and Cyclin D1 in breast cancer cells coupled with their increased proliferation. C3c was positive in glomeruli in direct immunofluorescent study. Engagement as an ethical imperative in harm reduction involving theolair 250 mg at-risk youth. The phase recovery can be realized with simple Viterbi algorithm and the frequency offset estimation (FOE) should be done with 25-QAM signal before 4-point fast Fourier transform (FFT).

danocrine cost 2019-08-08

Comprehensive sequence analysis of 24,783 barley full-length cDNAs derived from 12 clone libraries. Each protein contains an uninterrupted array of from four to 30 examples of the very widely occurring complement control protein (CCP, or sushi) module. Prevention of transmission of blood-borne infectious agents during blood glucose monitoring. In this study a nonlinear kinetic model was developed for the complexity estimation of large unknown polynucleotide populations and was experimentally verified. One wrong positive thrombosis occurred in a stenotic anastomosis with the 2D-inflow sequence. Unpredictable adverse results can ensue from blood transfusion therapies because of the donation of cells from a very large number of anonymous volunteers. Carnitine deficiency in critically ill patients is one aspect of these profound and complex changes associated with prolonged stay in ICU.

dose of danazol in endometriosis 2021-07-19

Part 6: Effects of lipophilicity and core structures on physicochemical and biological properties in vitro. The causes include rejection particularly humoral rejection, but also de novo autoimmune hepatitis, and recurrent disease. Management of metastatic breast cancer with second-generation antibody-drug conjugates: focus on glembatumumab vedotin (CDX-011, CR011-vcMMAE). Interestingly, the proliferation of tumor cells immensely depends on glycolysis, the Warburg effect, to ensure a sufficient amount of metabolic flux and bioenergetics for macromolecule synthesis and cell division. Stable PMP, AP, SSP, and HP detection rates throughout the workday occur under certain practice conditions, including the use of split-dose bowel preparation and/or moderated daily colonoscopist procedure loads. Spontaneous spinal epidural hematoma(SSEH)is a rare condition that typically presents with acute back pain and paraparesis or quadriparesis. Furthermore, since TLE subjects performed normally while taking therapeutic doses of multiple AEDs, the data suggest that these AEDs do not impair visual perception. type of antibiotic bactrim Cross-sectional statistical analysis of adiposity across large samples of adults differing by age, diet and lifestyle. In addition, the Aurora inhibitor acts synergistically with the vinca alkaloids but not with the taxanes in inhibiting cell proliferation and inducing apoptosis. This paper reports electrothermal actuation of silicon microcantilevers having integrated resistive heaters.

danocrine tablet obat apa 2017-08-21

We herein review the development of Nek2 as an oncology target and provide a succinct chronology of drug discovery campaigns focused on targeting Nek2. However, recent data from the Intergroup Trial, R 91-11 has placed concomitant chemoradiotherapy in the forefront as the standard of care for organ preservation. In addition, we previously showed that AKT2 is abundant in brown fat and skeletal muscle, tissues that are highly insulin responsive and that play a role in glucose metabolism. We investigated the role of laryngeal disease and dysfunction in the pathogenesis of GER-associated cough in nonasthmatic patients. The current Italian state of LHRs, BRs and Municipal Development Plans (MDPs) have been examined by a survey considering a sample of about 550 cities, with different demo graphic and geographic features, starting from the previous research work by Signorelli et al.

danocrine dosage 2018-06-11

With the ecological survey, however, no large changes in water quality could be determined at the sampling sites, due to the high degree of pollution present upstream of the discharge. The simple ventrolateral bend seen in this stem turtle, however, contrasts with the complex double-bend of extant turtles. Replication-defective recombinant adenoviral vectors carrying the rat ASPA gene (AxASPA) or Escherichia coli beta-galactosidase gene (AxLacZ), as a control, were constructed. Botanical drugs: challenges and opportunities: contribution to Linnaeus Memorial Symposium 2007. Studies on masticatory functions in patients with surgical mandibular reconstruction.

danazol 200 mg capsule 2018-05-06

Moreover, the expression of the adhesion-related kinases Pyk2 and Paxillin was up-regulated in parallel with the increase of Cbl proteins. Epidemiologic and clinicopathologic characteristics of tongue cancer in Iranian patients. RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs. This high level of IgG3 in uninfected primigravidae suggests a protective role of these antibodies in this susceptible group, highlighting the importance of VAR2CSA in general and of some of its variants still to be defined, in the induction of protective immunity to pregnancy malaria. Co-operation between clinical laboratory in exceeding the realms and knowledge intensiveness in the interpretation of the results could be needed. Triple phase bone scanning of an intraosseous ganglion: case report and discussion. Intimal dissection of the hepatic artery after thrombectomy as a cause of graft loss in lozol blood pressure medicine pediatric living-related liver transplantation. We present an algorithm to detect protein sub-structural motifs from primary sequence.

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