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Cytoxan (Cyclophosphamide)
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Cytoxan

Cytoxan is used to treat various types of cancer. It is a chemotherapy drug that works by slowing or stopping cell growth. Cytoxan also works by decreasing your immune system's response to various diseases.

Other names for this medication:
Cyclomet, Cyclophosphamide, Cycloxan, Cycram, Cycrame, Cydoxan, Cyphos, Eldamide, Endoxan, Ledoxan, Neophos, Neosar, Oncomide, Oncophos, Oncoxan

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Also known as: Cyclophosphamide

Description

Cytoxan is an antineoplastic. It works by stopping or slowing the growth or spread of certain cancer cells. Generic name of Cytoxan is Cyclophosphamide. Cytoxan is also known as Cyclophosphamide, Cycloxan. Brand name of Cytoxan is Cytoxan.

Dosage

This section provides information on the proper use of a number of products that contain cyclophosphamide. It may not be specific to Cytoxan Lyophilized. Please read with care.

Take this medicine only as directed by your doctor. Do not take more or less of it, and do not take it more often than your doctor ordered. The exact amount of medicine you need has been carefully worked out. Taking too much may increase the chance of side effects, while taking too little may not improve your condition.

Cyclophosphamide is sometimes given together with certain other medicines. If you are using a combination of medicines, make sure that you take each one at the proper time and do not mix them. Ask your doctor to help you plan a way to remember to take your medicines at the right times.

While you are using cyclophosphamide, it is important that you drink extra fluids so that you will pass more urine. Also, empty your bladder frequently, including at least once during the night. This will help prevent kidney and bladder problems and keep your kidneys working well. Cyclophosphamide passes from the body in the urine. If too much of it appears in the urine or if the urine stays in the bladder too long, it can cause dangerous irritation. Follow your doctor's instructions carefully about how much fluid to drink every day. Some patients may have to drink up to 7 to 12 cups (3 quarts) of fluid a day.

Usually it is best to take cyclophosphamide first thing in the morning, to reduce the risk of bladder problems. However, your doctor may want you to take it with food in smaller doses over the day, to lessen stomach upset or help the medicine work better. Follow your doctor's instructions carefully about when to take cyclophosphamide.

Cyclophosphamide often causes nausea, vomiting, and loss of appetite. However, it is very important that you continue to use the medicine even if you begin to feel ill. Do not stop taking this medicine without first checking with your doctor. Ask your doctor for ways to lessen these effects.

If you vomit shortly after taking a dose of cyclophosphamide, check with your doctor. You will be told whether to take the dose again or to wait until the next scheduled dose.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets): For the treatment of cancer: Adults—Dose is based on body weight and must be determined by your doctor. The usual dose is 1 to 5 milligrams (mg) per kilogram (kg) of body weight per day. Children—Dose is based on body weight and must be determined by your doctor. The usual dose is 1 to 5 mg per kg of body weight per day.

Overdose

If you overdose Cytoxan and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Cytoxan dosage information

Side effects

The most common side effects associated with Cytoxan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of cyclophosphamide in the elderly with use in other age groups, it is not expected to cause different side effects or problems in older people than it does in younger adults.

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We propose, that extraneural ependymoma should be considered in differential diagnosis for anaplastic tumors of the pelvic cavity. Trilateral retinoblastoma (TRb) is an intracranial neurogenic tumor associated with unilateral or bilateral retinoblastoma and has very poor prognosis. Patients who underwent chemotherapy and radiation for head and neck malignancies were evaluated for their ability to resume oral feeding following treatment. Functional outcome assessment of adults with right hemisphere brain damage. Subsequently the protostomes and later the arthropods gained many further clusters while MXEs got completely lost independently in several branches (vertebrates and nematodes) and species (for example the annelid Helobdella robusta and the salmon louse Lepeophtheirus salmonis). To elucidate the roles of adipose tissue and skeletal muscle in the early development of insulin resistance, we characterized gene expression profiles of isolated adipose cells and skeletal muscle of non-diabetic insulin-resistant first-degree relatives of type 2 diabetic patients using oligonucleotide microarrays. There are a lot of discussion about human behavior contingent with gravity which has not been discussed ever. This paper reveals an example of how the PDR principle may be applied in the field of human medicine. The antagonism of apoptosis afforded by prosurvival Bcl-2 proteins appeared to be specific for the GCs, as Bcl-2 and Bcl-x(L) blocked GC-induced apoptosis in T cell hybridomas but did not affect Fas or activation-induced apoptosis. Accordingly, prevention of hydroxyl radical formation through iron aldactone cost canada chelation cannot explain alone the beneficial effect of preventive DP treatment.

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Age-associated changes in mitochondrial mRNA expression and translation in the Wistar rat heart. TLXI, a novel type of xylanase inhibitor from wheat (Triticum aestivum) belonging to the thaumatin family. In this group of patients, pancreatic enzyme supplementation may provide symptomatic benefit. I examine how the attempt at standardizing medical services is simultaneously challenged and upheld within medical practice by illustrating the cognitivist assumptions upon which standardizing medical decision making is based, and showing how this is a product of a particular history of thought. Housekeeping proteins are typically chosen as internal loading controls for Western blot analysis because of their high, relatively constant expression. Moreover, loss of podocytes is a hallmark of diabetic and nondiabetic progressive CKD. Previous studies have identified the preventive effect of leisure-time physical activity (LTPA) on depression. In addition, many techniques are currently being developed for locoregional treatment of metastatic sites. Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation. This study is the first comprehensive dermatoglyphic research of Amis since 1960s, and its dermatoglyphic data will be useful for future research in anthropology, genetics and medicine.

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