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Cymbalta (Duloxetine)

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Cymbalta is used to treat depression and anxiety. Cymbalta may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions.

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Also known as: Duloxetine


Generic Cymbalta is developed by medical scientists to treat major depressive disorder and general anxiety disorder. It is an antidepressant in a group of drugs called selective serotonin and norepinephrine reuptake inhibitors. Generic Cymbalta affects chemicals in the brain that may become unbalanced and cause depression. Generic Cymbalta is also used to treat a chronic pain disorder called fibromyalgia, treat pain caused by nerve damage in people with diabetes (diabetic neuropathy) and to treat chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain.


Swallow a capsule whole with a drink of water. For depression and diabetic neuropathic pain: 60 mg once a day. Your doctor should determine the dose that is right for you. For generalised anxiety disorder: 30 mg once a day after which most patients will receive 60 mg once a day. Your doctor should determine the dose that is right for you. The dosage may be adjusted up to 120 mg a day based on individual response to Cymbalta. Take capsules at the same times every day. Talk with your doctor about how long you should keep taking Cymbalta. Do not stop taking Cymbalta, or change your dose, without discussing with your doctor. Cymbalta starts to work in most cases of depression or anxiety within 2 weeks of starting taking, but it may take 2-4 weeks before you feel better. Tell your doctor if you do not start to feel better after this time.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include vomiting, dizziness or drowsiness, seizures, fast heartbeats, fainting, or coma.


Store at a room temperature between 4 and 30 degrees C (39 and 86 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Cymbalta are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Cymbalta if you are allergic to Generic Cymbalta components. Do not take Generic Cymbalta if you're pregnant or you plan to have a baby, or you are a nursing mother. This medication can cause birth defects. Tell your doctor right away if you become pregnant during treatment. Be very careful with Generic Cymbalta if you're pregnant or you plan to have a baby. Do not take Generic Cymbalta if you are breast-feeding. Do not take Generic Cymbalta together with thioridazine (Mellaril), or an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate). A dangerous drug interaction could occur, leading to serious side effects. You must wait at least 14 days after stopping an MAO inhibitor before you can take Generic Cymbalta. After you stop taking Generic Cymbalta, you must wait at least 5 days before you start taking an MAOI. Generic Cymbalta can be not safety for children and people younger than 18 years old. Do not take Generic Cymbalta if you have any of these conditions:liver or kidney disease, seizures or epilepsy, a bleeding or blood clotting disorder, glaucoma, bipolar disorder (manic depression), a history of drug abuse or suicidal thoughts.Be careful if you drive or do anything that requires you to be alert. Generic Cymbalta may impair your thinking or reactions. Avoid alcohol. It can be dangerous to stop Generic Cymbalta using suddenly.

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