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Cefdox (Cefpodoxime)
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Cefdox

Cefdox is a prescription medicine used to treat the symptoms of various bacterial infections such as bronchitis, pneumonia, sinusitis, pharyngitis, tonsillitis, urinary tract infections, skin infections and gonorrhea. Cefdox may be used alone or with other medications.

Other names for this medication:
Belpro, Cefdolife, Cefdox, Cefirax, Cefobid, Cefodox, Cefolex, Cefomin, Cefoprox, Cefpodoxim, Cefpodoxima, Cefpodoxime, Cefpodoximum, Cefpolek, Ceftils, Cepdoxim, Cepodem, Cepodix, Desbac, Dofixim, Edrigard, Instana, Kindcef, Orelox, Otreon, Pedicef, Pocef, Podomexef, Podoxi, Rovantin, Sefox, Starin, Starpod, Tambac, Taxetil, Trucef, Victorin, Weijiexin, Ximeprox, Ximocef

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Also known as: Cefpodoxime

Description

Cefdox is an oral, third-generation cephalosporin antibiotic. It is active against most Gram-positive and Gram-negative organisms. Notable exceptions include Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis. Currently, it is only marketed as generic preparations in the USA, according to the FDA Orange Book. It is commonly used to treat acute otitis media, pharyngitis, sinusitis, and gonorrhea. It also finds use as oral continuation therapy when intravenous cephalosporins (such as ceftriaxone) are no longer necessary for continued treatment.

Cefdox inhibits cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis in cell walls. It has well established pharmacokinetic profile with absorption of 50%. It is indicated in community acquired pneumonia, uncomplicated skin and skin structure infections, and uncomplicated urinary tract infections.

Dosage

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

You or your child must take the tablets with food, while the oral liquid may be taken with or without food.

Shake the oral liquid well before each use. Measure the medicine with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

Keep using this medicine for the full treatment time, even if you or your child feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (suspension or tablets): For bronchitis: Adults and teenagers 12 years of age and older—200 milligrams (mg) every 12 hours. Children younger than 12 years of age—Use and dose must be determined by your doctor. For ear infections: Infants and children 2 months to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 milligrams (mg) per kilogram (kg) of body weight every 12 hours. Infants younger than 2 months of age—Use and dose must be determined by your doctor. For gonorrhea: Adults and teenagers 12 years of age and older—200 milligrams (mg) taken as a single dose. Children younger than 12 years of age—Use and dose must be determined by your doctor. For pneumonia: Adults and teenagers 12 years of age and older—200 milligrams (mg) every 12 hours. Children younger than 12 years of age—Use and dose must be determined by your doctor. For sinusitis: Adults and teenagers 12 years of age and older—200 milligrams (mg) every 12 hours. Infants and children 2 months to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 milligrams (mg) per kilogram (kg) of body weight every 12 hours. Infants younger than 2 months of age—Use and dose must be determined by your doctor. For skin infections: Adults and teenagers 12 years of age and older—400 milligrams (mg) every 12 hours. Children younger than 12 years of age—Use and dose must be determined by your doctor. For sore throat and tonsillitis: Adults and teenagers 12 years of age and older—100 milligrams (mg) every 12 hours. Infants and children 2 months to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 milligrams (mg) per kilogram (kg) of body weight every 12 hours. Infants younger than 2 months of age—Use and dose must be determined by your doctor. For urinary tract infections: Adults and teenagers 12 years of age and older—100 milligrams (mg) every 12 hours. Children younger than 12 years of age—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Cefdox and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Cefdox overdosage: abdominal cramps, diarrhoea, nausea, retching.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. After mixing the suspension store in a refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Do not freeze. Throw away unused portion after fourteen days. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Cefdox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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A multidisciplinary intensive care unit at a university medical center. Thirty minutes later, 0.2 mL of normal saline was injected subcutaneously into 1 inflamed site, and the opioid antagonist naloxone hydrochloride (80 microg in 0.2 mL) was injected subcutaneously into the other inflamed site. Evidence-based treatment of patients with ischemic cerebrovascular disease. ipomoeae group I and II strains but which showed no inhibitory function against other streptomycetes or other bacterial genera tested. Suppurated meningococcal meningitis with the cerebellar syndrome. One-dimensional (1D) conductive nanowire is one of the most important components for the development of nanosized electronic devices, sensors, and energy storage units. Endogenous GABA in the commissural subnucleus of the NTS inhibits the carotid chemoreceptor reflex via GABA A receptors in rats. Terminology used by pathologists in reporting on sudden infant deaths. (3) Six, nine and twelve month survival rates of inpatients treated with combined therapies were significantly higher than in simple stent implantation patients. The purpose of this research was to measure changes in selected plasma amino acids (AA) during two successive exercise trials to exhaustion.

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Marked histological changes were present in livers from animals fed sucrose prior to necropsy compared with fasted or chow-fed animals, and these changes were attributed to increased glycogen deposition in the sucrose-fed animals. Long-chain n-3 fatty acid supplementation in men increases resistance to activated protein C. The FFII is a composite score of global function based on a reproducible method of data collection and it differentiated between acid burn victims and provided objective comparative measures. Aggressive control measures for resistant Acinetobacter baumannii and the impact on acquisition of methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus in a medical intensive care unit. A series of 2-alkoxyimino-N-(2-isoxazolin-3-ylmethyl)acetamides and related compounds were synthesized and their antiviral activities against human influenza A virus were assessed. Abnormal pancreatic isoamylases, especially P4 and P5, are found in the serum of patients with choledochal cyst, which would point to a reflux of pancreatic juice into the biliary tract. Amiodarone-associated macroscopic T-wave alternans and torsade de pointes unmasking the inherited long QT syndrome.

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The FibreBag system is an economically necessary evolution of the earlier FibreCap system. Because of the scarcity of published cases and atypical presenting symptomatology this entity frequently causes a diagnostic as well as therapeutic dilemma. It is a member of the benzoylcyclohexane-1,3-dione family of herbicides, which are chemically derived from a natural phytotoxin obtained from the Californian bottlebrush plant, Callistemon citrinus. The decision for an intervention in diabetic eyes always requires a careful weighing of risks and benefits of surgery. Three populations of protons found during seed maturation, each with a different magnetic environment causing a different relaxation rate, were correlated with three fractions of water (structural, intracellular, and extracellular) that were observed during seed germination.

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The on-line monitoring of dissolved hydrogen gave valuable information about approaching process overload and can be a good complement to the conventional monitoring of volatile fatty acids. The interaction of the electrical double layers is also related to the charge characteristics on the Fe/Al oxides: the higher the positive charge density on Fe/Al oxides, the stronger the interaction of the electrical double layers between the soil colloid particles and the Fe/Al oxides. The identification of putative differentially expressed genes within genome regions containing QTL determining susceptibility of the mosquito, Aedes aegypti, to the malarial parasite, Plasmodium gallinaceum, was investigated using an integrated, targeted approach based on bulked segregant and differential display analysis. One patient had complete thrombosis of the deep dorsal penile vein and underwent subsequent penile prosthesis implantation. Role of vascular smooth muscle in the development of high altitude pulmonary hypertension: an interspecies evaluation. Structural and biophysical determinants of single Ca(V)3.1 and Ca(V)3.2 T-type calcium channel inhibition by N(2)O. It is concluded that the recombinative character of RNA viruses will hamper any attempt to set up a true phylogenetic taxonomy. Computer assisted management of information in an intensive care unit.

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The goal of the study was to evaluate the short-term radiographic results and complications of a percutaneous distal metatarsal osteotomy for hallux valgus. Protection of the central nervous system during thoracic aortic surgery. However, there are some other noncardiac conditions we should know. The neurofibromatosis type 1 (NF1) gene encodes a protein, neurofibromin, that shows homology with members of the GTPase-activating protein (GAP) family. The gain in peak capacity using long columns was evaluated by the separation of a tryptic bovine serum albumin digest with an LC-UV-mass spectrometry (MS) system and monolithic columns of different length (150 and 750 mm). Impact of sodium/proton exchanger 3 gene variants on sudden infant death syndrome. Ninety-four subjects were included in this comparative cross-sectional study of healthy (CTRL), primary-open-angle-glaucoma (POAG), ocular-hypertension (OHT), and normal-tension-glaucoma (NTG) volunteers. Zona-binding inhibitory factor-1 (ZIF-1), a glycoprotein in human follicular fluid, reduces the binding of spermatozoa to the zona pellucida. The Drosophila embryo is one of the most studied organisms in biological research, medical research, genetics, and developmental biology and has implications in the cure of human diseases.

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Systems of functional electrical stimulation (FES) have been demonstrated to enable some persons with paraplegia to stand and ambulate limited distances. All fifteen oral and maxillofacial surgery departments in Scotland were asked to provide copies of existing patient information materials on third molar surgery. Twelve specimens of ascitic and pleural effusion (APE) from patients with malignant diseases were examined quantitatively for growth promoting effect on three human cell lines and one human cell strain, by four different assay procedures. Effect of dietary carbohydrate and chlortetracycline on growth and excretion of phenols in rats fed extra tyrosine. The aim of this study was to investigate MMP-2 production in vascular tissue remote from the abdominal aorta. The relatively dark and warm environment on the scalp surface provides a welcoming environment for the superficial mycotic infections associated with many scalp conditions and for parasitic infestation. Total collections of milk, urine, and feces were obtained during the last 5 days of each infusion period. Structure-property relationships of a tetrapyrrolidinyl PNP-lariat ether and its complexes with potassium, sodium, and silver cations. Identification and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in brain. A multivariate risk analysis of selected playing surfaces in the National Football League: 1980 to 1989.

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Ambulatory oncology patients scheduled for diagnostic or therapeutic procedures with propofol anesthesia in the PICU were eligible for enrollment. We have developed a sensitive and specific radioimmunoassay for the quantitative determination of paraquat in plasma, urine, and bronchoalveolar lavage fluid using a monoclonal antibody. Then the following parameters were measured: malondialdehyde (MDA) concentrations in the homogenates and blood serum, glutathione (GSH) levels, the activity of CuZn-superoxide dismutase (SOD) and glutathione peroxidase (GPx), and glycaemia. Reconstitution and transcriptional analysis of chromatin in vitro. At least two different gene clusters conferring resistance to different races of P. Percentages of tumor-infiltrating monocytes (CD68, CCR5) and lymphocytes (CCR5, CD4, CD8 and CD25) were determined by immunohistochemistry.

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Cancer patients were represented as being people without a future who would lose their social and affective links. Breathlessness and exercise intolerance are the most common symptoms in COPD and progress relentlessly as the disease advances. These results suggest that duplex quantitative PCR methods are useful to detect and quantify C. The reason is that circles or near circular objects can heavily skew the distribution in favor of the cocircularity rule. We concluded that the studied IL-4 polymorphisms were not related to periodontal disease susceptibility in this African-American Brazilian population.

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Cardiovascular applications of magnetic resonance flow measurement. Few low income countries have emergency medical services to provide prehospital medical care and transport to road traffic crash casualties. In contrast, hard tissue was not seen over the IRM root-end filling. Seven of 11 patients in whom the duration was unknown were hypertensive. This is one reason why early resection of the primary tumor prevents liver metastasis. Clinical experiences with a new carbonic anhydrase inhibitor as an oral diuretic. Interpretation of osseous formations distal from the epicondylus medialis humeri. Extraction and Characterization of dentin phosphophoryn from human embryo.

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Crystallization and preliminary X-ray analysis of clade I catalases from Pseudomonas syringae and Listeria seeligeri. Platination of the (T2G4)4 telomeric sequence: a structural and cross-linking study. Strain T2 beta-galactosidase in Escherichia coli and preparation by using tailor-made metal chelate supports. An incidence study was conducted to identify all cases of first stroke in adult residents of northern Manhattan. Sixteen pairs of bilateral gingival recessions (Miller Class I and II) in 13 subjects were divided into two groups. A high-fidelity polymerase chain reaction (PCR) assay was used to amplify the 18S rRNA, 28S rRNA and beta-tubulin genes of the pathogen for phylogenetic analysis. Transforming growth factor (TGF)-beta1, TGF-beta2, IL-4 and IL-13 levels were measured in BAL fluid from 10 asthmatics and 9 non-asthmatic controls at baseline and then 1 day, 1 week and 2 weeks after SAC.

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Structure assignment in the solid state by the coupling of quantum chemical calculations with NMR experiments: a columnar hexabenzocoronene derivative. Genotyping of methicillin-resistant Staphylococcus aureus isolates obtained in the Northeast region of Brazil. Chronic Helicobacter pylori infection is the strongest known risk factor for the development of gastric cancer. Law, ethical codes, and the report of the CSSP survey on ethics policies. Extension of beef cattle genetic evaluation procedures to multibreed data sets is proposed as a way to allow inclusion of crossbred animals into current analyses and to provide comparisons between purebred animals of different breeds. This decrease was significantly prevented after administration of HCA (0.25, 0.5, or 1.0 mg/100 g). The 2 additional late deaths were unrelated to valve malfunction. Although the reason for this finding is unclear, it may contribute to high cardiovascular morbidity among African Americans. In accordance with morphological findings, the annual thymus involution in hibernating animals is close to the age-dependent thymus involution occurring in all mammals once in a lifetime.

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