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Biscolet (Norfloxacin)
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Biscolet

Biscolet is a fluoroquinolone antibiotic. Biscolet works by blocking DNA gyrase enzyme, which is responsible for production and repair of bacterial DNA. Blocking of DNA gyrase leads to bacteria death and prevents worsening of infection.

Other names for this medication:
Alenbit, Barazan, Baxicin, Chibroxine, Chibroxol, Effectsal, Epinor, Esclebin, Espeden, Flossac, Floxamicin, Floxen, Floxinol, Fluseminal, Janacin, Lemorcan, Lorcamin, Microxin, Niterat, Norax, Noraxin, Norbactin, Norflohexal, Norflok, Norflomax, Norflosal, Noxacin, Nufloxib, Ovinol, Parcetin, Quinabic, Rexacin, Sebercim, Senro, Setanol, Shinun, Urofos, Uronovag, Uticina, Xaflor, Xasmun

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Also known as: Norfloxacin

Description

Biscolet comes as a tablet to take by mouth. It is usually taken twice a day for 3 to 28 days. The length of treatment depends on the type of infection being treated. Your doctor will tell you how long to take Biscolet. Take Biscolet at around the same times every day and try to space your doses 12 hours apart. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Biscolet exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Take Biscolet at least 1 hour before or 2 hours after meals or after drinking milk or eating dairy products.

Swallow the tablets with a full glass of water.

You should begin to feel better during the first few days of your treatment with Biscolet. If your symptoms do not improve or if they get worse, call your doctor.

Take Biscolet until you finish the prescription, even if you feel better. Do not stop taking Biscolet without talking to your doctor unless you experience certain serious side effects listed in the IMPORTANT WARNING or SIDE EFFECT sections. If you stop taking Biscolet too soon or if you skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Biscolet is also sometimes used to treat certain infections of the stomach and intestines. Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Dosage

You should not use Biscolet if you have a history of myasthenia gravis, or if you are allergic to Biscolet or similar antibiotics such as ciprofloxacin (Cipro), gemifloxacin (Factive), levofloxacin (Levaquin), moxifloxacin (Avelox), ofloxacin (Floxin), and others.

You should not use this medication if you have ever had swelling or tearing of a tendon caused by taking Biscolet or similar antibiotics.

Before taking Biscolet, tell your doctor if you have a heart rhythm disorder, kidney or liver disease, muscle weakness or trouble breathing, joint problems, a condition called pseudotumor cerebri, a history of seizures, a history of head injury or brain tumor, low levels of potassium in your blood (hypokalemia), a personal or family history of Long QT syndrome, or if you have ever had an allergic reaction to an antibiotic.

Avoid taking antacids, vitamin or mineral supplements, sucralfate (Carafate), or didanosine (Videx) powder or chewable tablets within 2 hours before or after you take Biscolet.

Biscolet may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. These effects may be more likely to occur if you are over 60, if you take steroid medication, or if you have had a kidney, heart, or lung transplant. Stop taking Biscolet and call your doctor at once if you have sudden pain, swelling, tenderness, stiffness, or movement problems in any of your joints. Rest the joint until you receive medical care or instructions.

Overdose

If you overdose Generic Biscolet and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Biscolet dosage information

Side effects

The most common side effects associated with Biscolet are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Biscolet if you are allergic to Generic Biscolet components or to quinolone antibiotics such as ciprofloxacin, gatifloxacin, gemifloxacin, levofloxacin, lomefloxacin, moxifloxacin or ofloxacin.

Generic Biscolet should not be used for colds, flu, other virus infections, sore throats or other minor infections, or to prevent infections.

Be careful if you are pregnant, planning to become pregnant, or are breast-feeding.

Be careful if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement.

Be careful if you have seizures, brain disorders (e.g., cerebral arteriosclerosis, tumor, increased intracranial pressure), muscle disease/weakness (e.g., myasthenia gravis), heart problems (e.g., cardiomyopathy, slow heart rate, torsades de pointes, QTc interval prolongation), kidney disease, mineral imbalance (e.g., low potassium or magnesium), history of tendonitis/tendon problems.

When you take Generic Biscolet you should drink plenty of fluids.

Avoid alcohol and beverages containing caffeine (coffee, tea, colas), do not eat large amounts of chocolate.

Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors.

It can be dangerous to stop Generic Biscolet taking suddenly.

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Clinical awareness and early recognition are, therefore, emphasized. 2 Cases of goiter appearing during treatment with chorionic gonadotropin for late puberty in a young boy. Mapping of a new autosomal dominant non-syndromic hearing loss locus (DFNA43) to chromosome 2p12. We found that students at the early start school reported reduced sleep time and more sleepiness than their counterparts at the later starting school. The stress of change of posture makes both bladder dysfunction and sphincter weakness more evident. Feeding and dietary practices of nursing caries children in Riyadh, Saudi Arabia.

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The glucocorticoid-resistant clone CEM-C1-15 displays a combination of high constitutive JNK activity and dexamethasone-induced ERK activity with a weak induction of p38 upon glucocorticoid treatment. Regardless, many patients are not benefiting from treatment with drugs proven to help reduce morbidity and mortality. Treatment of antineutrophil cytoplasmic autoantibody-positive systemic vasculitis and glomerulonephritis with pooled intravenous gammaglobulin. Cross-sectional study using data on statin prescribing by age, sex and patient postcode for the period May to December 2002. These should be useful for a broad range of applications such as identification and subtyping of microorganisms from clinical samples, for identification of outbreak genotypes, for studies of micro-and macrovariation, and for population genetics. Isolation of human sweat glands was based on mechanical and enzymatic digestion of axillary skin. State self-esteem ratings in women with bulimia nervosa and bulimia nervosa in remission. Contribution of a practical dermatologist to contagious impetigo. In contrast, no structural modifications were detected at this time point.

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The ICRP protection quantities, equivalent and effective dose: their basis and application. Acute acalculous cholecystitis is now well recognised but is almost certainly not an homogeneous entity. Using CIA model we have studied the liposome trafficking following i.a. NADPH-dependent N-demethylation of aminopyrine and morphine was observed in the reconstituted system. Different features of angiogenesis between ovarian and breast carcinoma. The overproduction of biochemical mediators, and activation of leukocytes and endothelial cells, generated in thermally injured tissue, gives rise to both local and distant effects. The prevention and treatment of disease was as important as combat operations in the campaigns along the Mississippi River during the American Civil War. In the standard toxicology group, at the end of the exposure period, blood and urine samples were collected for clinical analyses, and five rats per group were sacrificed for pathologic examination. Recent studies provided evidence for a mitochondrial derived compartment in this parasite.

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The results of the present study provide a detailed mapping of neurons expressing vasoactive intestinal peptide/peptide histidine isoleucine-amide messenger RNA in the adult rat brain. Availability of released ATP at the nerve terminals was either increased via E-NTPDase inhibition or diminished by enhancing ATP hydrolysis with solCD39. The maximal excretion of both pregnandiol isomeres with the 24-hour urine was abserved in albino rats during the estrus and metestrus, and in guinea pigs and Cricetus auratus W.--during the estrus and diestrus. Most pigs had a peak demand for heat during the true daytime, but in two pigs the peak occurred at night. The colorimetric transitions observed in the assembly, corresponding to perturbation of the polydiacetylene framework, are induced only upon recognition of the displayed epitope by its specific antibody present in the aqueous solution. Distinguishing cardiac features of a novel form of congenital muscular dystrophy (Salih cmd). In this study, we investigated the activity of the MMP-9 promoter in driving exogenous gene expression in human cell lines. Decreased trabecular smooth muscle and caveolin-1 expression in the penile tissue of aged rats.

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It was clear that multiple compressions to the spinal cord caused more severe deterioration functionally and electrophysiologically as well as histologically than a single compression. Solitary resonance in the velocity-selective magnetic-optical activity spectrum of the (87)Rb D(2) line. The impact of mode of donor brain death on cardiac allograft vasculopathy: an intravascular ultrasound study. In this study, we developed a predictive program for Vibrio parahaemolyticus growth under various environmental conditions. We describe both aspects and present our recent results to illustrate the discussion. These analyses provide a method to partition correlation coefficients found in epidemiological studies into genetic and environmental components. Based on citations to journals in research and experimental medicine in 2005, Bayesian Markov chain Monte Carlo methods were used to estimate the uncertainty associated with these journal performance indicators. Our findings define an unexpected additional function for SipA postentry and reveal precise intracellular communication between effectors deployed by distinct T3SSs underlying SCV biogenesis. Glucocorticoids are commonly used antiinflammatory agents whose use is limited by side effects. The evaluation of long-term results of sclerotherapy in patients with symptomatic 1st and 2nd degree haemorrhoids.

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Primary hyperparathyroidism in children is an extremely rare condition. In contrast, beta2 integrins induced stimulation of Cdc42 that was independent of Src family members. A new radioreceptor assay was used to quantify changes in serum concentration of 1alpha,25-dihydroxyvitamin D3 in rats with low calcium or low phosphate diets. Influence of the Angioplasty Revascularization Investigation National Heart, Lung, and Blood Institute Diabetic Clinical Alert on practice patterns: results from the National Cardiovascular Network Database. The effect of electrical stimulation upon the direct tensile strength of the interfacial union between porous calcium aluminate implants (100 to 200 mu diameter pores) and bone was studied in the femurs of rabbits. Sexual dimorphism in the brain metabolic response to prenatal cocaine exposure. Achilles tendons: clinical relevance of neovascularization diagnosed with power Doppler US. Type 1A interruption of the aortic arch complex accompanied by mirror-image dextrocardia with situs inversus was diagnosed by counter-current aortography through the radial artery. A possible role of LIM mineralization protein 1 in tertiary dentinogenesis of dental caries treatment. This paper shows that our proprietary non-destructive inspection method can be used to effectively measure the thermal barrier performance of the thermal barrier coating used to coat gas turbine hot parts by the results of numerical analysis and laboratory experiments.

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The aim of this study was to determine whether the reduction of the left ventricular mass in hypertensive patients treated with captopril is accompanied by an improvement of the diastolic filling indexes. Although the sample was small, and results may not apply to other exposures in different health care environments, these data provide some evidence that women who enroll in TIS pregnancy outcome studies do not have a substantially different pregnancy risk profile than women who do not. It is hypothesized that the reduction in biofilm formation by these compounds in a flow system occurs through a contact-dependent effect. ELISA of the VEGF-A protein in the culture medium revealed that the gene-delivered ATF repressed the expression rate of the VEGF-A gene under hypoxia condition. There were statistically significant linear correlations between exercise-induced increases in FRC and decreases in FVC and between increases in Raw and FRC. We review evidence that human learning is representationally flexible in a way that challenges both configural and elemental theories. Meta-analysis was performed by using the Forest plot review if feasible.

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Some of the tracer particles were engulfed by the alprostadil pellets cost tissue histiocytes, but most of the particles entered into lymphatic and blood capillaries. Evidence for the biological modulation of IL-1 activity: the role of IL-1Ra. Hypnosis is user friendly when it is simple to employ, and yields rapid, effective, and clinically significant results. Reports of insomnia were a significant predictor of all five daytime functioning measures, which is consistent with previous research. Hypophosphatemic rickets with normoalkaliphosphatemia, ossification of the posterior longitudinal ligament and yellow ligament. Evaluation of the ocular hypotensive response of serotonin 5-HT1A and 5-HT2 receptor ligands in conscious ocular hypertensive cynomolgus monkeys. Structural, biochemical, and functional characterization of the calcium sensor neurocalcin delta in the inner retinal neurons and its linkage with the rod outer segment membrane guanylate cyclase transduction system. Because such actions imply ligand-receptor binding, we quantified mRNAs encoding the two known forms of insulin receptor in rat liver and yolk sac, two endodermally derived tissues shown to express insulin genes, between gestation days (E) 13 and E21 (mid-organogenesis to parturition).

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Auditory function in persons of different age groups according to the date of sonant and whispering speech audiometry. Elevation of matrix metalloproteinases (MMPs) in multiple sclerosis and impact of immunomodulators. Physical gelation in rod-like associating polymer solutions is analyzed by computer simulations and by mean field models. PELP1-mediated induction of aromatase requires functional Src and PI3K pathways. These results suggest that Go may regulate neuronal differentiation through modulation of gene expression of what is the normal dosage of klonopin target genes such as N-type calcium channels. Continued hemodynamic monitoring also provides prompt objective information as to success or failure of therapeutic interventions. The general practitioner is often confronted with this problem and has to decide which investigations are to be ordered. Children aged 1-16 years with acute severe asthma were enrolled if they showed little improvement with three nebulisers (combined salbutamol and ipratropium) administered over an hour and systemic steroids. Twenty-eight amino acid residues involved in most noncovalent interactions between trimeric protein subunits in the capsid of the parvovirus minute virus of mice were truncated individually to alanine, and the effects on capsid assembly, thermostability, and conformation were analyzed.

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