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Azitrox (Azithromycin)
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Azitrox

Azitrox is used to treat certain bacterial infections, such as bronchitis; pneumonia; sexually transmitted diseases (STD); and infections of the ears, lungs, sinuses, skin, throat, and reproductive organs.

Other names for this medication:
Amovin, Azicine, Azicu, Azilide, Azithrex, Azithro, Azithromycin, Azithromycinum, Azithrox, Azitrim, Azitrin, Azitro, Azitrovid, Azomex, Azomycin, Azyth, Binozyt, Koptin, Kromicin, Macromax, Maczith, Medimacrol, Neofarmiz, Novozithron, Odazyth, Oranex, Ribotrex, Sitrox, Tromic, Tromix, Vinzam, Zertalin, Zibac, Zibramax, Zifin, Zithrocin, Zithromycin, Zitrim, Zitroneo, Zycin

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Also known as: Azithromycin

Description

Azitrox (Azitrox tablets and Azitrox for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Azitrox has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Azitrox is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Azitrox, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Azitrox is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Azitrox for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

A nurse or other trained health professional will give you this medicine. This medicine is given through a needle placed in one of your veins. This medicine is given slowly, so the needle will remain in place for about an hour.

Your doctor may give you a few doses of this medicine until your condition improves, and then you may be switched to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Detailed Azitrox dosage information

Overdose

If you overdose Azitrox and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Azitrox overdosage: discomfort feeling in stomach, diarrhea, retching, nausea.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not refrigerate or freeze the Zmax® extended-release oral suspension. After water has been added to the powder, use the dose within 12 hours and throw away any unused liquid after your dose.

You may store the Azitrox® oral liquid at room temperature or in the refrigerator. Do not freeze the bottle. Do not keep the oral liquid for more than 10 days. Throw away any unused liquid after all doses are completed.

Detailed Azitrox dosage information

Side effects

The most common side effects associated with Azitrox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take antacids that contain aluminum or magnesium within 2 hours before or after you take Azitrox. This includes Acid Gone, Aldroxicon, Alternagel, Di-Gel, Gaviscon, Gelusil, Genaton, Maalox, Maldroxal, Milk of Magnesia, Mintox, Mylagen, Mylanta, Pepcid Complete, Rolaids, Rulox, and others. These antacids can make Azitrox less effective when taken at the same time.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking Azitrox and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Avoid exposure to sunlight or tanning beds. Azitrox can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

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We observed the phosphorylation of PKC-delta and p38 MAP kinase within 1 min after thrombin challenge of human umbilical vein endothelial cells. We evaluated the effects of very high daily intake of plant stanols (8.8 g/day) as esters on cholesterol metabolism, and serum levels of plant sterols and stanols. Cancer mortality in a surveillance cohort of German males formerly exposed to asbestos. Twenty additional compounds identified were present only in the alcoholic sample. We defined the gorge proper radius as the measure for the extent of gorge opening.

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We therefore have investigated the pathological and immunohistochemical features of the TMJ of a transgenic mouse that over expresses the human form of TNFalpha. METHODS: Nerve regeneration was assessed using gait analysis of returning hind limb function, histology, and morphometry. The purpose of this study was to validate automated quality assessment (QA) software for CT colonography (CTC) by comparing results obtained with the software with results of interpretation by radiologists in the assessment of colonic distention and surface area obscured by residual fluid. Some issues related to sentinel lymph nodes with cervical cancer. In vivo IFN-gamma induced CXCL16 expression in murine atherosclerotic lesions. The people lacked factors of diet, body bulk and tight clothing that have been postulated to be important in other populations. In a second experiment, adaptation to oblique unidirectional motion produced threshold elevation for a wider range of test directions than adaptation to a cardinal direction. In the RVO group, two peaks of current densities were detected at the right superior region and left thoracic region and these two diploles appeared to be from the right and left ventricular derived cardiac currents, respectively. The results provide further evidence of the validity of the TSS. An observation of leprosy situation in Surat district from 2001 to 2006.

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