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Azilide

Azilide is an antibiotic useful for the treatment of a number of bacterial infections. It may be used for a number of sexually transmitted infections including chlamydia and gonorrhea infections. Also it includes middle ear infections, strep throat, pneumonia, traveler's diarrhea, and certain other intestinal infections. Along with other medications, it may also be used for malaria.

Other names for this medication:
Azalid, Azicip, Azilide, Azimit, Aziphar, Azithin, Azitrin, Azomycin, Aztrin, Bactrazol, Clearsing, Fabramicina, Magnabiotic, Momicine, Neofarmiz, Ordipha, Tanezox, Zemycin, Zibac, Zicho, Zirocin, Zistic, Zithrogen, Zithromycin, Zitroneo, Zocin, Zomax, Zycin

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Also known as: Azithromycin

Description

Azilide injection is used to treat bacterial infections in many different parts of the body. It is also used to prevent Mycobacterium avium complex (MAC) disease in patients infected with the human immunodeficiency virus (HIV).

Azilide belongs to the class of drugs known as macrolide antibiotics. It works by killing bacteria or preventing their growth. However, Azilide will not work for colds, flu, or other virus infections. Azilide injection may be used for other problems as determined by your doctor.

Azilide is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, Azilide is used in certain patients with the following medical condition: Trachoma (treatment).

Dosage

This section provides information on the proper use of a number of products that contain azithromycin. It may not be specific to Azilide Tri-Pak. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

You may take Azilide® oral liquid or tablets with or without food.

Shake well the bottle of Azilide® oral liquid before each use. Measure your dose correctly with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

Measure the Zmax® extended-release oral suspension with a marked measuring spoon, syringe, or cup. You or your child must take this medicine within 12 hours after it has been mixed with water. It is best to take the Zmax® extended-release oral suspension on an empty stomach or at least 1 hour before or 2 hours after a meal. If your child does not use all of the medicine in the bottle, throw it away after you give the dose.

If you or your child vomits within one hour of taking the Zmax® extended-release oral suspension, call your doctor right away to see if more medicine is needed.

Keep using this medicine for the full treatment time, even if you or your child feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

If you are taking aluminum or magnesium-containing antacids, do not take them at the same time that you take Azilide®. These medicines may keep azithromycin from working properly. However, you can take antacids with Zmax®.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (extended-release suspension): For treatment of pneumonia: Adults—2 grams (g) once as a single dose. Children weighing 34 kilograms (kg) or more—Dose is based on body weight and must be determined by your doctor. The dose is usually 2 grams once a day, taken as a single dose. Children 6 months of age and older weighing less than 34 kg—Dose is based on body weight and must be determined by your doctor. The dose is usually 60 milligrams (mg) per kilogram (kg) of body weight once a day, taken as a single dose. For treatment of sinusitis: Adults—2 grams (g) once a day as a single dose. Children—Use and dose must be determined by your doctor. For oral dosage forms (suspension or tablets): For treatment of infections: Adults—500 to 2000 milligrams (mg) once a day, taken as a single dose. Depending on the type of infection, this may be followed with doses of 250 to 500 mg once a day for several days. Children 6 months of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 10 to 30 milligrams (mg) per kilogram (kg) of body weight once a day, taken as a single dose. Depending on the type of infection, this may be followed with doses of 5 to 10 mg per kg of body weight once a day for several days. Children younger than 6 months of age—Use and dose must be determined by your doctor. For treatment of pharyngitis or tonsillitis: Adults—500 milligrams (mg) on Day 1 (the first day), taken as a single dose. Then, 250 mg on Day 2 through Day 5. Children 2 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 12 milligrams (mg) per kilogram (kg) of body weight once a day for 5 days. Children younger than 2 years of age—Use and dose must be determined by your doctor.

Overdose

If you overdose Azilide and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Azilide overdosage: discomfort feeling in stomach, diarrhea, retching, nausea.

Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not store the liquid longer than 10 days.

Side effects

The most common side effects associated with Azilide are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Azilide Z-Pak if you are allergic to it, or if you have ever had:

jaundice or liver problems caused by taking Azilide Z-Pak; or a severe allergic reaction to similar drugs such as clarithromycin, erythromycin, or telithromycin.

Azilide Z-Pak oral should not be used to treat pneumonia in people who have:

cystic fibrosis; an infection after being in a hospital; an infection in the blood; a weak immune system (caused by diseases such as HIV/AIDS or cancer); or in older adults and those who are ill or debilitated.

Tell your doctor if you have ever had:

pneumonia; liver or kidney disease; myasthenia gravis; low levels of potassium in your blood; a heart rhythm disorder; or long QT syndrome (in you or a family member).

It is not known whether this medicine is effective in treating genital ulcers in women.

Tell your doctor if you are pregnant or breastfeeding. Taking Azilide Z-Pak while breastfeeding may cause diarrhea, vomiting, or rash in the nursing baby.

Azilide Z-Pak is not approved for use by anyone younger than 6 months old. This medicine should not be used to treat a throat or tonsil infection in a child younger than 2 years old.

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The induction of calcified nodules was visualized by von Kossa stain. Bone marrow-derived immature DCs pre-exposed to tick saliva showed reduced migration towards macrophage inflammatory protein (MIP)-1alpha, MIP-1beta and regulated upon activation, normal T cell expressed and secreted (RANTES) chemokines in a Boyden microchamber assay. A threshold in sonication intensity also exists, allowing optimization of both parameters and the formation of nanocapsules of controlled size with a rather narrow distribution. The cytosolic entry of diphtheria toxin catalytic domain requires a host cell cytosolic translocation factor complex. This study set out to characterize the features of experimental infection by simian immunodeficiency virus in mandrill (SIVmnd) (Mandrillus sphinx), cynomolgus macaque (Macaca fascicularis), rhesus macaque (Macaca mulatta), chimpanzee (Pan troglodytes), African green monkey (Cercopithecus pygerythrus), baboon (Papio cynocephalus) and human cells. This can result in inadvertent tearing of the mucoperiosteal flap with extrusion of graft material into the antrum. Stabilization of pancreatic ribonuclease A by immobilization on Sepharose-linked antibodies that recognize the labile region of the enzyme. This study shows blood-borne factors are responsible and that ablating the host natural killer (NK) cell response greatly enhances the survival of such donor myoblasts.

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The survey was conducted from the beginning of January 1997 to the end of December 1997. The homology between the two genes extends throughout most of the coding sequences, including sequences encoding the DNA-binding domain and putative activation domains. Intraoperative ultrasound with a special small transducer is possible, but it is difficult to reach the intraspinal area by this means, because it is surrounded by bones. In an attempt to inhibit the function of both MAP kinases simultaneously we constructed a loss-of-function mutant version of NtMEK2, which, in transient transformation assays, led to an inhibition of germination in the transformed pollen grains. famata in the activation of innate immunity and the contribution of human epithelial cells in local defenses against such exogenous stimulations as C. Here, we introduce a new approach to the concomitant determination of absolute protein concentration and the stoichiometry of phosphorylation at predefined sites. Molecular identification and localization of cellular titin, a novel titin isoform in the fibroblast stress fiber. Short- and long-term black tea consumption reverses endothelial dysfunction in patients with coronary artery disease. Sleep-disordered breathing (SDB) is a very common disorder and is the major sleep-related risk factor for cerebrovascular disease.

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Coadministration of WIN55,212-2 prevented the effects of SR141716A on inhibitory control in the 5-CSRTT. The EC50 values of these aliphatic chloramines from the Microtox test decreased by roughly one order of magnitude as a result of chlorination. It risperdal consta dose equivalent is, therefore, suggested that, in these types of patients, bone and brain scans be reserved for those with symptoms referable to the neurologic or skeletal systems. By contrast, it was always monophasic positive in simian nonhuman primates, although prosimiae gave monophasic negative waves. Because cadherins control the overall state of cell contact, cytoskeletal organization, and the establishment of many other kinds of cell interactions, it remains unknown whether E-cadherin directly transduces growth inhibitory signals. This demonstrates that cricoid pressure is effective in preventing reflux at intragastric pressures which are encountered clinically and the presence of the laryngeal mask airway does not compromise this. Effect of digitalis on contractility of the failing right and left ventricles during exercise (authors transl). The mass and the attached cerebellar falx were homogeneously enhanced by contrast medium. An organism identified as Chromobacterium lividum was isolated from processed poultry in Georgia.

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Thus, LZM might be important for preventing endotoxemia in Gram-negative sepsis with the treatment of antibiotics. We show that COMMD1 competes with the chaperone heat shock protein HSP90beta for binding to the NH(2)-terminal DNA-binding and heterodimerization domain of HIF-1alpha to regulate HIF-1alpha stability together with HSP70. The natural history of chronic myeloid leukemia (CML) progresses from a relatively benign chronic phase into a fatal blast crisis, which resembles acute leukemia, but is incurable by chemotherapy. Previous studies reported that prostatic inflammation was highly prevalent in PE. A propriety temporary ureteral drainage stent (TUDS, Boston Scientific/Microvasive, Natick, Massachusetts) was developed to satisfy this goal with the added advantages of biodegradability and spontaneous passage. Green tea catechins have diverse pharmacological effects such as anticarcinogenic and antioxidant activities.

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