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Avascare (Ezetimibe)
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Avascare

Avascare is a type of medicine used to lower cholesterol. It's used to treat high blood cholesterol. This is when you have too much of a fatty substance called cholesterol in your blood. Avascare is a non-statin lipid-lowering medication that inhibits absorption of dietary cholesterol by blocking the Niemann-Pick C1-Like 1 protein (NPC1L1).

Other names for this medication:
Atofast, Atolife, Atorvik, Avascare, Bitorva, Etimibe, Ezedoc, Ezentia, Ezerem, Ezetib, Ezetimiba, Ezetimibe, Ezetrol, Ezevas, Ezibloc, Eziwa, Ezzicad, Filet, Imbibe, Lipezet, Liponorm, Mactor, Orvas, Razel, Redustat, Statix, Storvas, Tonact, Visvas, Zeteze, Zetica, Zetimax, Zetivas, Zient, Zivast

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Also known as: Ezetimibe

Description

Avascare (ezetimibe) reduces the level of total cholesterol and LDL (bad) cholesterol in the blood.

Avascare is used to treat high cholesterol in people who cannot control their cholesterol levels by diet and exercise alone.

Avascare works to reduce the amount of cholesterol your body absorbs. You should stay on a cholesterol-lowering diet while taking this medicine.

Avascare is sometimes given together with other cholesterol-lowering medications.

Dosage

Usual Adult Dose of Avascare for Hyperlipidemia:

10 mg orally once a day Uses: -For use as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin) as an adjunct to diet to reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin to reduce elevated total-C and LDL-C levels in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Adult Dose of Avascare for Homozygous Familial Hypercholesterolemia:

10 mg orally once a day Uses: -For use as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin) as an adjunct to diet to reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin to reduce elevated total-C and LDL-C levels in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Adult Dose of Avascare for Sitosterolemia:

10 mg orally once a day Uses: -For use as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin) as an adjunct to diet to reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin to reduce elevated total-C and LDL-C levels in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Pediatric Dose for Hyperlipidemia:

10 years or older: 10 mg orally once a day Uses: -For use as monotherapy or in combination with a statin as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with a fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin for the reduction of elevated total-C and LDL-C in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Pediatric Dose for Homozygous Familial Hypercholesterolemia:

10 years or older: 10 mg orally once a day Uses: -For use as monotherapy or in combination with a statin as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with a fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin for the reduction of elevated total-C and LDL-C in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Pediatric Dose for Sitosterolemia:

10 years or older: 10 mg orally once a day Uses: -For use as monotherapy or in combination with a statin as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with a fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin for the reduction of elevated total-C and LDL-C in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Detailed Avascare dosage information

Overdose

If you overdose Generic Avascare and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Avascare are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Avascare if you are allergic to Generic Avascare components. Do not take Generic Avascare if you're pregnant or you plan to have a baby, or you are a nursing mother. Generic Avascare can ham your baby. Generic Avascare cannot be taken by children under 10 years. Generic Avascare cannot be used together with fibrates (such as Lopid, Tricor). Try to be careful using Generic Avascare if you take cyclosporine (such as Sandimmune, Neoral, Gengraf); another cholesterol "lowering drugs fenofibrate (such as Tricor), (gemfibrozil (such as Lopid), clofibrate (such as Atromid-S), lovastatin (such as Altocor, Mevacor), pravastatin (such as Pravachol), fluvastatin (such as Lescol) or simvastatin (such as Zocor), atorvastatin (such as Lipitor). It can be dangerous to use Generic Avascare if you suffer from or have a history of liver disease. If you experience drowsiness and dizziness while taking Generic Avascare you should avoid any activities such as driving or operating machinery. Avoid alcohol. Keep low-cholesterol and low-fat diet. Do not stop taking Generic Avascare suddenly.

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Previous studies have shown that elderly adults are less able than young adults to recover balance by stepping, apparently due to reductions in step length and step speed. Alpha-Lactalbumin is found in some breast cancer organ cultures. How chromatin-mediated transcription regulates the beginning of mammalian development is currently unknown. Ninety-eight patients underwent a urodynamic study (URD) to assess LUT disturbances. In addition, sequencing of ribosomal ITS regions and AFLP analysis suggested that some species annotations in public culture collections may be inaccurate. Thus, the use of CMV PCR assays with optimal performance characteristics did not increase the detection of potentially infectious blood components beyond that provided by current serologic screening assays. Methods hydrea 500 mg uses include draining of the water in lagoons with or without coagulants and flocculants, or using presses or centrifuges. Over the past 20 years, antimicrobial resistance has become an increasing problem. The gap/gapless processing debate in the psycholinguistics literature contrasts two processing models: one that assumes the trace-based Government and Binding (or Principles and Parameters) Grammar and the (augmented) Active Filler Strategy and one that assumes the traceless Dependency Categorial Grammar and the Principle of Dependency Formation. Ethanol production from sorghum by a dilute ammonia pretreatment.

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The established clinical efficacy of PDT treatment to prevent AMD progression coincides with an encouraging patient satisfaction after the treatment. Somatic symptoms are common among patients on CHD and they appear to be associated with emotional distress (anxiety and depression) that influences significantly the perceived health status. Data from in vitro whole-cell patch recordings showed differences in frequency of subthreshold membrane potential oscillations in entorhinal neurons that correspond to different positions along the dorsal-to-ventral axis, supporting a model of physiological mechanisms for grid cell responses. The evolution of refraction seems to be different in eyes with anisometropia and it is still to be understood whether it is fixation or reduced fixation that leads to a myopic shift. (3) What is the effect of the Asp/Glu in the Zn-His-Asp/Glu triad on the Zn-bound water protonation state?. Cellular repopulation and recovery of the phytogemagglutinine (PHA) responding cell pool in the thymus of sublethally irradiated mice. The significance of bovine spongiform encephalopathy epidemics for transfusion medicine.

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Patients with possible contraindications were removed to define the use of therapies specifically among clearly eligible patients. Our results suggest a potential of the EHBD and gall bladder as useful transplantable sources for liver injury. Resistance arteries isolated from gluteal biopsies were mounted on small-vessel myographs, and concentration responses were determined for vasoconstrictors (noradrenaline, angiotensin II, and endothelin-I) and vasodilators (acetylcholine, bradykinin, spermine-NONOate, and nifedipine). The value of reinforcing intracranial aneurysms with plastic coating. The acid-catalyzed condensation of the triethoxysilane pendant groups of triethoxysilane-functionalized polybutadiene chains at the air/water interface successfully led to the formation of an insoluble crosslinked material which could be directly removed from the water surface.

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