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Atenerate (Nifedipine)

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Atenerate is used to treat high blood pressure or angina (chest pain). For high blood pressure: Atenerate works by relaxing and expanding the blood vessels. This makes the blood flow more easily and lowers blood pressure. Lower blood pressure reduces the strain on your heart. For angina: Atenerate works by relaxing and expanding the arteries supplying the heart. This allows more blood and oxygen to reach the heart and decreases the strain on it. Your angina attacks will be less severe and less frequent if there is less strain on the heart.

Other names for this medication:
Buconif, Cordipin, Depicor, Duranifin, Epilat, Fenamon, Fenidina, Jutadilat, Myogard, Nicardia, Nidipine, Nifecor, Nifedel, Nifedical, Nifedicor, Nifedigel, Nifedipina, Nifehexal, Nifeslow, Niften, Nipidin, Ospocard, Oxcord, Pressolat, Tensomax, Valni

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Atenerate OROS. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Atenerate and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Atenerate are:

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It is unclear whether hospital complexity-the range of services and technologies provided-affects outcomes and in what direction. LGG has in vitro effects on enhanced IL-10 and IFN-gamma release of mononuclear cells. The binding of a single ligand significantly increases opening, although four ligands are required for full activation. An agar-microchamber cell-cultivation system: flexible change of microchamber shapes during cultivation by photo-thermal etching. The goal of this article is to raise awareness of TACO amongst hospital staff to facilitate faster recognition and earlier intervention in future events. Experimental and computational investigation into the electronic structures of 3a and 3b revealed that they are most accurately described as containing a high spin iron(ii) center that is antiferromagnetically coupled to a singly reduced bis(imino)pyridine ligand. OSBP might also be a PI 4-kinase effector in poliovirus infection and could be involved in replication of other viruses that require PI 4-kinases. A grounded theory methodology was used in this study to capture the perspectives of the nurse managers interviewed about their role. Selective separation of furfural and hydroxymethylfurfural from an aqueous solution using a supported hydrophobic deep eutectic solvent liquid membrane. Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase.

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We aimed to test the hypothesis that placental growth is mediated, either directly or indirectly, by fetal insulin. The blood of the examinees was tested for NO metabolites--nitrites and nitrates--according to N. Extent of aminoglycoside interference in the pyrogallol red-molybdate protein assay depends on the concentration of sodium oxalate in the dye reagent. The mechanism by which Su exaccerbates pulmonary hypertension is, however, unclear. Aerobic exercise reduces visceral adipose tissue in dose-response fashion among patients with stage I-III colon cancer. We believe that the repeat region at the C-terminus should be a candidate for a subunit vaccine against erysipelas. Large inverted duplications in the human genome form via a fold-back mechanism. Determination of functional residual air by body plethysmography. Affected and unaffected members of three families with BCM were examined clinically and underwent electrophysiological and detailed psychophysical testing. Relating receptors by ligand chemistry organizes biology to reveal unexpected relationships that may be assayed using the ligands themselves.

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Analysis of 396 consecutive patients with primary surgery for advanced ovarian cancer FIGO stages IIB-IV operated before the introduction of the quality management program 1997-2000, or during the introduction years 2001-2003, or after establishing 2004-2008. BLAST results are visualized by spreadsheets and graphs and are full-text searchable. Our selection of literature is intended to illustrate significant insights, concepts and understanding, as well as the current scope of using molecular simulations for understanding polymorphic transitions in an accessible way, rather than claiming completeness. A possible mode of origin and the clinical importance of this variation are discussed. The article presents clinical and pathomorphological findings related to a case of the Rendu-Osler-Weber disease and demonstrates the difficulties of its differential diagnosis. The sterile insect technique for the management of the spotted wing drosophila, Drosophila suzukii: Establishing the optimum irradiation dose. Based on this model, we are able to estimate the settling time, power-spectral density (PSD), and signal to noise ratio (SNR) of general affinity-based biosensors. (1) Given that SOBIR1 appears to be a crucial component of RLP-containing complexes, we aimed to identify additional proteins interacting with SOBIR1.

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Primary human osteoblasts were exposed to dexamethasone in vitro and microarray based transcriptome profiling completed. Separate associations of waist and hip circumference with lifestyle factors. Interstitial Granulomatous Variant of Scleromyxedema-A Diagnostic Pitfall. Glucose metabolism in adult survivors of severe acute malnutrition. Initial effects of the National PCV7 Childhood Immunization Program on adult invasive pneumococcal disease in Israel. DREZ coagulations for deafferentation pain related to spinal and peripheral nerve lesions: indication and results of 79 consecutive procedures. Electrophysiological assessments of cognition and sensory processing in TBI: applications for diagnosis, prognosis and rehabilitation.

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Fibrosis control is mainly associated with regression of necroinflammatory activity, which is the main treatment component in autoimmune hepatitis. Vaccines have traditionally been designed to induce antibody responses and have been licensed on their capacity to induce high titers of circulating antibody to the pathogen. The magnetic guidance system consists of a magnetic device attached to the asymmetric stent and an external homogeneous magnetic field of 0.1 T. The growth-promoting effect of bGH was significantly enhanced by mixing it with bovine anti-peptide antibodies prior to administration. Characterization of microsomal aniline hydroxylase of rainbow trout, Salmo gairdneri. The adjustment of treatment was associated with a reduction in asthma symptom scores in all subjects. Perioperative thermal insulation: minimal clinically important differences?. Our patient was a 4-month-old girl with complex single-ventricle anatomy and a small-caliber superior vena cava. umbrosa, both in accumulating As and metals in the below-ground plant parts and in translocating As to the fronds.

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The means of their flagellar curvature ratios and linear indices were intermediate between helical and hyperactivated mean values. The disease was different in the two patients: one was of the lymphoid type, acute lymphoblastic leukemia type L1, and the other was of the myeloid type, acute nonlymphoblastic leukemia type M2. Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport. The radius of the best-fit sphere for the anterior corneal surface (rant) and posterior corneal surface (rpost), mean radius of simulated keratometry (rsimK), and central corneal thickness were obtained. Surgical treatment for ischial pressure sores with gracilis myocutaneous flap. Our results showed that developmental expression patterns of DH and DHR1 are quite similar in transgenic silkworms: both genes are highly expressed in the mid to late stages of pupae and are most highly expressed in day-6 pupae but are expressed at very low levels in other developmental stages.

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Blocking effect of McN-A-343 on cardiac slowing produced by vagal stimulation. We asked whether mechanotransduction also occurs during non-integrin mediated migration by examining the motion of the social amoeba Dictyostelium discoideum, which is thought to bind non-specifically to surfaces. Artificial neural network coding of the child attachment interview using linguistic data. Careful investigations of the film topography are carried out by atomic force microscopy (AFM), and X-ray photoelectron spectroscopy (XPS) is used to check the chemical composition of the film at different stages. In turn, CREB and MEIS1 binding sites seem to depend on the presence of NF-Y site to induce Mstn P/E. The technique employed measuring pressure at two sites within the aorta and measuring multiple time differences between each pair of pressure waves. Suitability for tumor measurement was expressed as the number of measurable diameters. Subcutaneous challenge of mice with lipopolysaccharide (LPS) from gram negative bacteria, produced an intestinal microvascular lesion causing fluid exudation into the lumen of the intestine and diarrhea. Combined hormonal contraception and risk of venous thromboembolism within the first year following pregnancy. Assuming constancy of evolutionary rate, diversification of the representative alleles of the three human ABO lineages (A101, B101, and O02) was estimated at 4.5 to 6 million years ago.

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Genes and enzymes of ectoine biosynthesis in halotolerant methanotrophs. Although neuro-ophthalmologists must still rely on time-consuming history taking and careful clinical examination, the three modalities described herein can provide objective proof regarding clinical diagnoses in selected cases, saving time and avoiding costly neurologic investigations. The percentage of patients prescribed inappropriate AST, inappropriate AST at ICU transfer and hospital discharge, doses of inappropriate AST, and adverse effects associated with AST use were compared between periods using chi-square tests. Brain-derived estrogen exerts anti-inflammatory and neuroprotective actions in the rat hippocampus. Esophageal varices are a dangerous complication of liver cirrhosis. We obtained an antibody, anti-inner root sheath cells antibody (anti-IRSC Ab), that reacted with the inner root sheath (IRS) cells especially trichohyalin granules (THG). Medical records of critically ill patients with acute stroke were reviewed.

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demonstrate that an activator of G protein signaling (AGS3) is persistently upregulated in the prefrontal cortex after cessation of chronic cocaine treatment. The long-term effect of lifestyle interventions on UcOC and insulin secretion has not been investigated. The basal and final protein levels depend on the strength of the promoter that directs the transcripcional activator as well as the relative orientation of the two genes in the same plasmid. brasiliensis exhibited splenomegaly and significant decrease in catalase activity, and protein and non-protein thiol content compared to animals infected with the other species. In the extent of lymph node metastasis (N category), survival rates differed significantly among the 4 groups (N0, N1, N2, N3) in the JPS classification and also did significantly between the 2 groups (N0, N1) in the UICC classification. Controls with intact pineal glands demonstrated significant decrease in cocaine-induced conditioned place preference at night compared to daytime, whereas pinealectomized mice did not show any diurnal differences. Test-retest and interrater and intrarater reliability of the video analysis measures was assessed.

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Dynamics of the emergence and establishment of a newly dominant genotype of zofran sl dosing Japanese encephalitis virus throughout Asia. As it requires a matching between an ambiguous-continuous information (the inner feeling) and a consensual-discrete label (the emotional term), this process probably involves a great degree of uncertainty. Ligand-binding prediction for ErbB2, a key molecule in the pathogenesis of leprosy. The assessment of Health Related Quality of Life (HRQL) is important in people with dementia as it could influence their care and support plan. Bangladesh introduced the maternal and perinatal death review system in 2010. Despite the growing awareness of the importance of gene-gene interactions, the paradigm of detectable effects of individual variants remains the cornerstone of genome association studies with tagSNPs. No excretion was seen in four kidneys and eight kidneys were not examined urographically because of uremia. The European Union and the United States are seeing an increasing number of biosimilar applications and approvals.

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Failure to detect any specific vehicle for the infection led to observations of kitchen practice. IL-33 works as a positive regulator of TSLP-DC-OX40L axis that initiates and maintains the Th2 cell-mediated inflammatory responses, and therefore, it would be a new therapeutic target for the treatment of allergic disorders. Mechanism of copper-induced ovulation by the incubation experiment of the anterior pituitary gland. Afterwards, the optimized method was validated in terms of sensitivity, linearity, seroquel medication control substance accuracy and precision. Cytotoxicity, genotoxicity and intracellular distribution of the Auger electron emitter (65)Zn in two human cell lines. Chronic inflammatory demyelinating polyradiculoneuropathy and anesthesia: a case series. We conducted a cognitive task analysis (CTA) study to observe ten general dentists (five general dentists and five general dental faculty members, each with more than two years of clinical experience) examining three simulated patient cases using a think-aloud protocol. A new anti-arrhythmic agent: a prolonged-action derivative of quinidine. Thirty male volunteers aged 18-40 years were randomised to receive either three doses of 30 microg MSP3-LSP or 0.5 ml of tetanus toxoid vaccine. Hyperactive cells showed ultrastructural evidence of increased secretory and digestive activity and were associated with proliferation and more pronounced complement deposition.

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A caused significantly less enamel loss than C, with no statistically significant differences from B at any time points measured. Ab initio calculation of the phonon spectra on ZrB(12) excellently agrees with the experimental results. All evidence indicates that the H2----L mutation, selection, and evolution to predominance occurred within the 7-day span of individual infections. Finally, the available TCR structures provide an opportunity to re-evaluate the molecular basis for intrathymic positive selection as well as the mechanisms that make a given TCR neither infinitely specific, nor so flexible that it engages productively any MHC-binding peptides. CsgD, the master regulator of biofilm formation, activates the synthesis of curli fimbriae and extracellular polysaccharides in Escherichia coli. Parallel investigations of blood and alveolar air in the diagnosis of lethal carbon monoxide poisoning. The lymphoid cell appeared to undergo neoplastic transformation into a cell with a large pale nucleus, often with a prominent nucleolus and variable cytoplasm. Case report with presentation of the fundus photography, fluorescein angiography (FA) and optical coherence tomography (OCT) findings.

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Radical surgery: effect on quality of life and pain in chronic rhinosinusitis. Electroencephalogram (EEG) showed generalized slow wave activity. Our study provides evidence that LGE-CMR is useful in the diagnosis and prognosis of EMF through quantification of the typical pattern of FT deposition. Photochemical and Photobiological Activity of Ru(II) Homoleptic and Heteroleptic Complexes Containing Methylated Bipyridyl-type Ligands. Histochemical studies of the ovary of white rats following unilateral castration. Catheter-based renal sympathetic denervation for resistant hypertension: durability of blood pressure reduction out to 24 months. Our findings suggest that a significant fraction of purported cases were not confirmed. Group II PAKs (PAK4-6) regulate a wide variety of cellular functions, and PAK deregulation has been linked to tumor development.

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Although the action of some natural and nutritional agents on BPH tissue has been demonstrated experimentally, data from prospective clinical trials are not available. The objective of this study was to determine whether a gradient in Tg protein level exists in patients with DTC. However, less is known about the role of neurabin in hippocampal plasticity and its possible effect on behavioral functions. Translocation of labeled indolyl-3-acetic acid in sieve tubes of Vicia faba. We reviewed MRI and SPECT images in 10 patients with septo-optic dysplasia (SOD). citri (Xcc), the causative agent of bacterial citrus canker, has affected citriculture worldwide. Science fiction is a modern mythology that, beyond a technical exterior, has lasting value in its ability to reflect the human condition. Acute rapamycin nephrotoxicity in native kidneys of patients with chronic glomerulopathies. The other portal flow phantom was fabricated as a thin walled tubular latex structure for use in water tanks with Ultrasound imaging.

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The histone deacetylation inhibitor, suberoylanilide hydroxamic acid (SAHA), can induce growth arrest in transformed cells. Arsenic trioxide exerts its action by accelerating cell apoptosis, while all-trans retinoic acid by inducing cell differentiation. These effects of dexfenfluramine probably result from changes in the metabolism of 5-HT in the CNS and consequent alterations in hormonal balance. With this microenvironment, appropriate cumulus cell-oocyte signaling governs oocyte developmental competence, defined as the ability of the oocyte to complete meiosis and undergo fertilization, embryogenesis, and term development. This change is accompanied by a reduction in the amount of conjugally replicated DNA in the donor cells that can be isolated as closed-circular plasmid DNA. In vitro selection techniques were used to evolve an initial library of approximately 10(14) unique RNA sequences through eight cycles of selection to yield several active sequence families. The Gram-positive infections are a problem with increasing significance in the newborn period.

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Abstracts of the 2009 meeting of the International Society for Research in Human Milk and Lactation (ISRHML), October 8-11, Lima, Peru. In Phase 1, five focus groups were conducted with patients to determine their beliefs, concerns and issues with using identification in remote patient monitoring devices. Secular trends in the physical development of newborn infants during the 20th century till the beginning of the 21st century. Participants were 52 mothers of children recruited from a university can you take mobic with blood pressure medicine medical center. Relationship of ferritin to symptom ratings children with attention deficit hyperactivity disorder: effect of comorbidity. Teashirt binds to, and requires, Armadillo for the naked cell-fate choice in the larval trunk. Forty-eight were retrieved and assessed for eligibility by the authors. We retrospectively analyzed the outcomes of 20 women who underwent vaginal cuff excision repairs of a vesicovaginal fistula after total hysterectomy.

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We found a correlation between the RBC-component and thrombus attenuation, which improves validation of thrombus attenuation on NCCT as an imaging biomarker for stroke management. Anteroposterior fields to the pelvis deliver a daily dose of 2.7 Gy, while lateral fields confined to the prostate and seminal vesicles deliver an additional daily dose of 0.7 Gy. Voluntary Step Execution Test in both single- and dual-task conditions is a simple and safe examination which can potentially and effectively predict future falls, with no added value to dual- over single-task condition. Effects of vehicle speed on flight initiation by Turkey vultures: implications for bird-vehicle collisions. Should elderly patients undergo additional surgery after non-curative endoscopic resection for early gastric cancer?.

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We use a noninvasive real-time detection of the transport, enabling feedback control of the system. Thallium intoxication: a specific antidote, supportive therapy and clinical evaluation. The different fractions are deposited in the paper and can subsequently be handled independently by simply cutting the paper for downstream processing and analyses. This study aimed to evaluate the ACT, Japanese version (ACT-J) as a predictor of asthma control as defined by the GINA 2006 guidelines in actual clinical practice. An 81-year-old woman with progressive cough was hospitalized 2 weeks following transcutaneous pacemaker implantation. The potential benefits of using our system include the higher accuracy of acute stroke lesion definition, the reduced time and procedure of calculating the volume of a lesion, and providing 3D reconstruction image of stroke patients, which can effectively assist doctors in making more accurate diagnoses and treating patients in a more convenient way. Fresnel zone plates (FZPs) play an essential role in high spatial resolution x-ray imaging and analysis of materials in many fields. Urine samples were collected at day zero, four and eight, and analyzed by HILIC-MS. Prospective investigation of cutaneous lesions of 24 Sicilian patients revealed that 17 were taches noires from norvasc generic 10mg patients with a documented diagnosis of boutonneuse fever.

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