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Asacol (Mesalamine)
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Asacol

Asacol is used to treat and prevent mild to moderately active ulcerative colitis (an inflammatory bowel disease). It works inside the bowels to reduce inflammation and other symptoms of the disease. This medicine is available only with your doctor's prescription.

Other names for this medication:
Canasa, Mesacol, Mesalamine, Pentasa, Rowasa, Tidocol, Walasa

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Also known as: Mesalamine

Description

Asacol HD (mesalamine) affects a substance in the body that causes inflammation, tissue damage, and diarrhea.

Asacol HD delayed-release 800mg tablets are used to treat moderately active ulcerative colitis in adults.

Dosage

This section provides information on the proper use of a number of products that contain salicylate. It may not be specific to Asacol 800. Please read with care.

Take this medicine after meals or with food (except for enteric-coated capsules or tablets and aspirin suppositories) to lessen stomach irritation.

Take tablet or capsule forms of this medicine with a full glass (8 ounces) of water. Also, do not lie down for about 15 to 30 minutes after swallowing the medicine. This helps to prevent irritation that may lead to trouble in swallowing.

For patients taking aspirin (including buffered aspirin and/or products containing caffeine):

Do not use any product that contains aspirin if it has a strong, vinegar-like odor. This odor means the medicine is breaking down. If you have any questions about this, check with your health care professional. If you are to take any medicine that contains aspirin within 7 days after having your tonsils removed, a tooth pulled, or other dental or mouth surgery, be sure to swallow the aspirin whole. Do not chew aspirin during this time. Do not place any medicine that contains aspirin directly on a tooth or gum surface. This may cause a burn. There are several different forms of aspirin or buffered aspirin tablets. If you are using: chewable aspirin tablets, they may be chewed, dissolved in liquid, crushed, or swallowed whole. delayed-release (enteric-coated) aspirin tablets, they must be swallowed whole. Do not crush them or break them up before taking. extended-release (long-acting) aspirin tablets, check with your pharmacist as to how they should be taken. Some may be broken up (but must not be crushed) before swallowing if you cannot swallow them whole. Others should not be broken up and must be swallowed whole.

To use aspirin suppositories:

If the suppository is too soft to insert, chill it in the refrigerator for 30 minutes or run cold water over it before removing the foil wrapper. To insert the suppository: First remove the foil wrapper and moisten the suppository with cold water. Lie down on your side and use your finger to push the suppository well up into the rectum.

To take choline and magnesium salicylates (e.g., Trilisate) oral solution:

The liquid may be mixed with fruit juice just before taking. Drink a full glass (8 ounces) of water after taking the medicine.

To take enteric-coated sodium salicylate tablets:

The tablets must be swallowed whole. Do not crush them or break them up before taking.

Unless otherwise directed by your medical doctor or dentist:

Do not take more of this medicine than recommended on the label, to lessen the chance of side effects. Children up to 12 years of age should not take this medicine more than 5 times a day.

When used for arthritis (rheumatism), this medicine must be taken regularly as ordered by your doctor in order for it to help you. Up to 2 to 3 weeks or longer may pass before you feel the full effects of this medicine.

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For aspirin For oral dosage forms (short-acting tablets, chewable tablets, and delayed-release [enteric-coated] tablets): For pain or fever: Adults and teenagers—325 to 500 milligrams (mg) every three or four hours, 650 mg every four to six hours, or 1000 mg every six hours as needed. Children 11 to 12 years of age—320 to 480 mg every four hours as needed. Children 9 to 11 years of age—320 to 400 mg every four hours as needed. Children 6 to 9 years of age—320 to 325 mg every four hours as needed. Children 4 to 6 years of age—240 mg every four hours as needed. Children 2 to 4 years of age—160 mg every four hours as needed. Children up to 2 years of age—Dose must be determined by your doctor. For arthritis: Adults and teenagers—A total of 3600 to 5400 mg a day, divided into several smaller doses. Children—A total of 80 to 100 mg per kilogram (kg) (32 to 40 mg per pound) of body weight a day, divided into several smaller doses. For preventing a heart attack, stroke, or other problems caused by blood clots: Adults—Most people will take 81, 162.5, or 325 mg a day or 325 mg every other day. Some people taking aspirin to prevent a stroke may need as much as 1000 mg a day. Children—Use and dose must be determined by your doctor. For oral dosage form (chewing gum): For pain: Adults and teenagers—2 tablets every four hours as needed. Children 6 to 12 years of age—1 or 2 tablets (227 mg each) up to four times a day. Children 3 to 6 years of age—1 tablet (227 mg) up to three times a day. Children up to 3 years of age—Dose must be determined by your doctor. For long-acting oral dosage form (extended-release tablets): For pain: Adults and teenagers—1 or 2 tablets twice a day. Children—The long-acting aspirin tablets are too strong for use in children. For arthritis: Adults and teenagers—1 or 2 tablets twice a day, at first. Your doctor will then adjust your dose as needed. Children—The long-acting aspirin tablets are too strong for use in children. For rectal dosage form (suppositories): For pain or fever: Adults and teenagers—325 to 650 mg every four hours as needed. Children 11 to 12 years of age—325 to 480 mg every four hours as needed. Children 9 to 11 years of age—325 to 400 mg every four hours as needed. Children 6 to 9 years of age—325 mg every four hours as needed. Children 4 to 6 years of age—240 mg every four hours as needed. Children 2 to 4 years of age—160 mg every four hours as needed. Children up to 2 years of age—Dose must be determined by your doctor. For arthritis: Adults and teenagers—A total of 3600 to 5400 mg a day, divided into several smaller doses. Children—A total of 80 to 100 mg per kilogram (kg) (32 to 40 mg per pound) of body weight a day, divided into several smaller doses.

For aspirin and caffeine For oral dosage forms (capsule): For pain or fever: Adults and teenagers—325 to 500 milligrams (mg) of aspirin every three or four hours, 650 mg of aspirin every four to six hours, or 1000 mg of aspirin every six hours as needed. Children 9 to 12 years of age—325 to 400 mg every four hours as needed. Children 6 to 9 years of age—325 mg every four hours as needed. Children up to 6 years of age—Aspirin and caffeine capsules are too strong for use in children up to 6 years of age For preventing a heart attack, stroke, or other problems caused by blood clots: Adults—325 mg a day or every other day. People who take smaller doses of aspirin will have to use a different product. Some people taking aspirin to prevent a stroke may need as much as 1000 mg a day. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): For pain or fever: Adults and teenagers—325 to 500 mg of aspirin every three or four hours, 650 mg of aspirin every four to six hours, or 1000 mg of aspirin every six hours as needed. Children 9 to 12 years of age—325 to 400 mg every four hours as needed. Children up to 9 years of age—Aspirin and caffeine tablets are too strong for use in children up to 9 years of age. For arthritis: Adults and teenagers—A total of 3600 to 5400 mg of aspirin a day, divided into several smaller doses. Children—A total of 80 to 100 mg per kg (32 to 40 mg per pound) of body weight a day, divided into several smaller doses. For preventing a heart attack, stroke, or other problems caused by blood clots: Adults—325 mg a day or every other day. People who take smaller doses of aspirin will have to use a different product. Some people taking aspirin to prevent a stroke may need as much as 1000 mg a day. Children—Use and dose must be determined by your doctor.

For buffered aspirin For oral dosage forms (tablets): For pain or fever: Adults and teenagers—325 to 500 milligrams (mg) of aspirin every three or four hours, 650 mg of aspirin every four to six hours, or 1000 mg of aspirin every six hours as needed. Children 11 to 12 years of age—One or one and one-half 325-mg tablets every four hours as needed. Children 9 to 11 years of age—One or one and one-fourth 325-mg tablets every four hours as needed. Children 6 to 9 years of age—One 325-mg tablet every four hours as needed. Children 4 to 6 years of age—Three-fourths of a 325-mg tablet every four hours as needed. Children 2 to 4 years of age—One-half of a 325-mg tablet every four hours as needed. Children up to 2 years of age—Dose must be determined by your doctor. For arthritis: Adults and teenagers—A total of 3600 to 5400 mg of aspirin a day, divided into several smaller doses. Children—A total of 80 to 100 mg per kilogram (kg) (32 to 40 mg per pound) of body weight a day, divided into several smaller doses. For preventing a heart attack, stroke, or other problems caused by blood clots: Adults—325 mg a day or every other day. People who take smaller doses of aspirin will have to use a different product. Some people taking aspirin to prevent a stroke may need as much as 1000 mg a day. Children—Use and dose must be determined by your doctor.

For buffered aspirin and caffeine For oral dosage form (tablets): For pain or fever: Adults and teenagers—325 or 421 milligrams (mg) of aspirin every three or four hours, 650 mg of aspirin every four to six hours, or 842 mg of aspirin every six hours as needed. Children 11 to 12 years of age—One or one and one-half 325-mg tablets, or one 421-mg tablet, every four hours as needed. Children 9 to 11 years of age—One or one and one-fourth 325-mg tablets every four hours as needed. Children 6 to 9 years of age—One 325-mg or 421-mg tablet every four hours as needed. Children 4 to 6 years of age—Three-fourths of a 325-mg tablet every four hours as needed. Children 2 to 4 years of age—One-half of a 325-mg tablet every four hours as needed. Children up to 2 years of age—Dose must be determined by your doctor. For arthritis: Adults and teenagers—A total of 3600 to 5400 mg of aspirin a day, divided into several smaller doses. Children—A total of 80 to 100 mg per kilogram (kg) (32 to 40 mg per pound) of body weight a day, divided into several smaller doses. For preventing a heart attack, stroke, or other problems caused by blood clots: Adults—162.5 or 325 mg (one-half or one 325-mg tablet) a day or 325 mg every other day. People who need smaller doses of aspirin will have to use a different product. Some people taking aspirin to prevent a stroke may need as much as 1000 mg a day. Children—Use and dose must be determined by your doctor.

For choline salicylate For oral dosage form (oral solution): For pain or fever: Adults and teenagers—One-half or three-fourths of a teaspoonful every three hours, one-half or one teaspoonful every four hours, or one or one and one-half teaspoonfuls every six hours as needed. Children 11 to 12 years of age—2.5 to 3.75 mL (one-half to three-fourths of a teaspoonful) every four hours as needed. This amount should be measured by a special measuring spoon. Children 6 to 11 years of age—2.5 mL (one-half of a teaspoonful) every four hours as needed. This amount should be measured by a special measuring spoon. Children 4 to 6 years of age—1.66 mL every four hours as needed. This amount should be measured by a special dropper or measuring spoon. Children 2 to 4 years of age—1.25 milliliters (mL) (one-fourth of a teaspoonful) every four hours as needed. This amount should be measured by a special dropper or measuring spoon. Children up to 2 years of age—Dose must be determined by your doctor. For arthritis: Adults—A total of five and one-half to eight teaspoonfuls a day, divided into several smaller doses. Children—A total of 0.6 to 0.7 mL per kilogram (kg) (0.25 to 0.28 mL per pound) of body weight a day, divided into several smaller doses.

For choline and magnesium salicylates For oral dosage forms (oral solution or tablets): For pain or fever: Adults and teenagers—A total of 2000 to 3000 milligrams (mg) a day, divided into two or three doses. Children weighing more than 37 kg (90 pounds or more)—2200 mg a day, divided into two doses. Children weighing up to 37 kilograms (kg) (about 89 pounds)—A total of 50 mg per kg (20 mg per pound) of body weight a day, divided into two doses.

For magnesium salicylate For oral dosage form (tablets): For pain: Adults and teenagers—2 regular-strength tablets every four hours, up to a maximum of 12 tablets a day, or 2 extra-strength tablets every eight hours, up to a maximum of 8 tablets a day. Children—Dose must be determined by your doctor.

For salsalate For oral dosage forms (capsules or tablets): For arthritis: Adults and teenagers—500 to 1000 milligrams (mg) two or three times a day, to start. Your doctor will then adjust your dose as needed. Children—Dose must be determined by your doctor.

For sodium salicylate For oral dosage forms (tablets or delayed-release [enteric-coated] tablets): For pain or fever: Adults and teenagers—325 or 650 milligrams (mg) every four hours as needed. Children 6 years of age and older—325 mg every four hours as needed. Children up to 6 years of age—This medicine is too strong for use in children younger than 6 years of age. For arthritis: Adults and teenagers—A total of 3600 to 5400 mg a day, divided into several smaller doses. Children—A total of 80 to 100 mg per kilogram (kg) (32 to 40 mg per pound) of body weight a day, divided into several smaller doses.

Overdose

If you overdose Generic Asacol and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Asacol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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A literature search, review, and summary of findings of recent studies relating to factors associated with recovery, as well as interventions for rehabilitation and promotion of healing of the injured spinal cord was performed. Telephones, telemedicine, and a technologically neutral coverage policy. Management, largely supportive, may consist of administering intravenous fluids, anti-emetics, and activated charcoal depending on the time of exposure. Furthermore, measurements with graded mixtures of HSV-tk-expressing cells and control cells were made. The presence of NPs in asthma patients is associated with an increase in asthma severity. We collected data on 94 renal cell carcinoma cases with bone metastasis treated at 3 tertiary referral centers. In vitro isoflavonoid production in callus from different organs of Pueraria lobata (Wild.) Ohwi.

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Injury and activation of tubular proximal epithelial cells (TEC) play central roles in renal tubulointerstitial fibrosis (TIF), but its mechanisms remain obscure. However, sensitive PCR assays on tissues collected from 3-year-old fish additionally identified ghrelin transcripts in pyloric caecae, intestine, and in immature ovary and testis. Excessive weight gain was observed in premature infants who subsequently developed NEC. Rapid and specific detection of toxigenic Staphylococcus aureus: use of two multiplex PCR enzyme immunoassays for amplification and hybridization of staphylococcal enterotoxin genes, exfoliative toxin genes, and toxic shock syndrome toxin 1 gene. A combination of intraarticular ropivacaine, morphine, and ketorolac followed by intermittent injections of ropivacaine as needed provided better pain relief, less morphine consumption, and lodine 300 mg 10 film tablet improved patient satisfaction compared with the control group. Impaired chondrocyte repair mechanisms, due to inflammation, oxidative stress and autophagy, play important roles in the pathogenesis of osteoarthritis. Disruption of the AD motifs did not diminish the ability of the PGC-1alpha protein to associate with the PEPCK or CPT-I genes.

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Analysis of the phenotypes of the animals heterozygous for two unlinked genes revealed that jud-1 and jud-3 act synergistically in a gene dose-dependent manner. Historically, treating military surgeons pioneered the early documentation of leg hernias observed in active military recruits. Size Regulation and Stability Enhancement of Pt Nanoparticle Catalyst via Polypyrrole Functionalization of Carbon-Nanotube-Supported Pt Tetranuclear Complex. However, such phenomena did not occur in punctured host pupae (mimic-parasitization). It fails to confirm previous reports of an association between COMT and cognitive function. We therefore investigated the signaling pathways by which Wnt5b influences differentiation. The transport properties (solubility, diffusivity, and permeability) of pure and gas mixtures in the membranes were calculated and the results of the simulations were compared with the available experimental data. All octa- and hexasaccharide fractions tested were unable to activate bFGF. The number of involved nodes, the metastases to internal mammary nodes, and to the extra axillary nodes are reclassified. Ten samples of coolants with a different state of wear, including four fresh fluids, were analyzed.

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Repeat ADR-related hospitalizations have consistently increased in elderly Australians from 1980 to 2003. Proteins from kernel extracts of corn genotypes were analyzed by several methods of polyacrylamide gel electrophoresis. Our results support the hypothesis that MS significantly affects certain cancers in a protective or associative manner. An evaluation of the carotid bifurcation and of the intracranial circle by angio-spiral computed tomography. Bioarchaeological investigation of ancient Maya violence and warfare in inland Northwest Yucatan, Mexico. Religious participation and substance use behaviors in a Canadian sample of homeless people. The right-ventricular outflow tract was reconstructed with a 8mm PTFE vascular graft. The comparisons show fewer animals using the site with the highest resource than predicted by the input matching rule, that is, undermatching is found. Like many sexually dimorphic ungulates, bighorn sheep, Ovis canadensis, form sexually segregated groups. Combined acoustic and electric hearing: preserving residual acoustic hearing.

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Traumatic pseudoaneurysm of the hepatic artery after percutaneous liver biopsy and laparoscopic cholecystectomy in a patient with biliary cirrhosis: a case report. Using anterograde labeling technique with Phaseolus vulgaris leucoagglutinin (PHA-L), we demonstrated the arborization pattern of a single preganglionic axon in the superior cervical ganglion (SCG) and stellate ganglion (STG). Each patient was made to donate a unit of homologous blood prior to surgery. In a combined positron emission tomography (PET) and computed tomography (CT) system, the CT images can be used for attenuation correction as well as for image fusion. However, the extent of the impairments observed in learning or memory tasks remains unclear. Laboratory data, including blood count and electrolytes, showed leukocytosis and azotemia. The aim of this study was to evaluate the level of microbial contamination of metalworking coolants as a potential source of harmful biological agents in three different metal industry plants in Poland. In this review, recent advances in the clinical therapy of osteosarcoma, including results from the European Osteosarcoma Intergroup trial demonstrating the efficacy of a short intensive two drug protocol are discussed as well the evolving role of ifosfamide. This model was evaluated retrospectively in 26 additional patients, yielding a mean prediction error of -0.4 mg/l (-3.0-2.2 mg/l) and a mean absolute prediction error of 4.7 mg/l (3.2-6.2 mg/l) based on two-level feedback.

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The microbiological quality of the polluted spring was monitored during intervals over the following 12 months and compared with others in the area. HF-10 SCS is free of paresthesia and associated with significantly better coverage of axial lower back pain. Through implementation we maintained quality while impacting length of stay, ICU utilization, phlebotomy, and cost. nerii, during extinction/recolonization events, to better understand the population ecology of this invasive species. Although a countermeasure must be taken to decrease mortality, the introduction of hepatectomy with bile duct resection would provide a better cancer-free surgical margin than bile duct resection alone for hilar bile duct carcinoma. In quantitative analysis of the agyric cortex of a ten-month-old patient, relative immaturity of basal dendritic arborization was apparent together with a bipolar configuration of dendritic development of the pyramidal neurons.

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Modeling of annexin A2-Membrane interactions by molecular dynamics simulations. In the preoperative assessment of the invasion stage of gastric carcinoma (TNM), ultrasound endoscopy is the elective imagistic investigation for predicting the grade of invasion of the gastric wall while CT examination is a more accurate assessment of lymph node extension and metastases, the precise definition of invasion stage being only the result of histopathological examination on surgical specimens. We compare 272 match cost functions that are built from component parts in the context protonix generic cost without insurance of four global stereopsis frameworks with a data set consisting of 57 stereo image pairs at three different variances of synthetic sensor noise. Applied force during vitreoretinal microsurgery with handheld instruments. We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). Usually, hospitals and private doctors are well equipped with computers.

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Model experiments to evaluate the protective role of thiols and other reductants against oxidative damage. Therefore, routine intracervical balloon placement should be considered for saline infusion sonohysterogram. All applications for late termination of pregnancy in 1986 were reviewed by Nordentoft et al, and access to all applications from 2011 was granted by the abortion committees and the Appeals Board. The clinical use of tryptanthrin should focus on its pharmacodynamics and safety study in these tissues. A step-by-step case report describes the rehabilitation program for visual dysfunction of a 52-year-old woman, beginning 2 years post-trauma. Attributional style and combat-related posttraumatic stress disorder. Acute determinants of the hangout interval in the pulmonary circulation. Twenty-one patients had pursuit paresis, 18 abnormal vestibulo-ocular reflex (VOR) cancellation, 15 abnormal convergence, 13 abnormal optokinetic nystagmus (OKN), 12 conjugate gaze limitation, nine nystagmus, nine saccadic paresis, and six abnormal fixation. Positive influence of the proposed method for recovering what drug can replace ativan of central hemodynamic parameters in patients with cardiac and/or respiratory dysfunction and the outcome of early phases of AP were ascertained.

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Systematic assessment of the benefits and caveats in mining microbial post-translational modifications from shotgun proteomic data: the response of Shewanella oneidensis to chromate exposure. To our knowledge, we are reporting the first use of Therakos CELLEX and Spectra Optia PMN protocol for WBC depletion. The target compounds were screened for their anti-osteoporotic ( ultram 25 mg picture agonist) and anti-uterotrophic (antagonist) activities and were found to be moderately active. A multidisciplinary approach is required for the proper evaluation and treatment of patients with PNES. Factors Influencing the Application of a Biopsychosocial Perspective in Clinical Judgement of Chronic Pain: Interactive Management with Medical Students.

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The C-flex IOLs showed good functional results and significantly lower PCO formation than the earlier model Centerflex IOL. In ontogenesis of lower monkeys, the development of the main nervous processes of the higher nervous activity (learning, memory, etc.) takes place gradually depending on the age of a baby and the level of integrative activity of the brain. Ultrastructurally and immunohistologically, most of the junctions were detected on the processes of follicular dendritic cells (FDC) enveloping nondividing centrocytes in the light zone of germinal centers where B-cell selection is thought to take place. The relationships between hemoglobin conversion and lipid peroxidation in hemosomes under effects of fatty acids were studied. Each possible associated factor of GC/premalignant and precursor lesions was evaluated by univariate and multivariate logistic regressions. It is expected that the nature of propagation of electromagnetic signals is distinct in each of these tissues.

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To maximize the business value of projects, they must incorporate a prospective evaluation component that includes asking the right research questions, identifying an appropriate time period, including a targeted population, articulating a replicable intervention, and determining the correct statistical analysis. Plasma NT-ANP levels at 30 min after exercise reflect ANP albenza tablet levels at maximum exercise and left ventricular overload during exercise. Disaggregation of collective dose--a worked example based on future discharges from the Sellafield nuclear fuel reprocessing site, UK. Three paediatric cases of blastomycosis, apparently acquired in or near Toronto, Ontario, a region not known to be endemic for this disease, are described. Both contrast media provided adequate visualization for the diagnosis of Kawasaki disease, but the contrast of the images and the visualization of details were better with iopamidol than with ioxaglate. We describe a new complication after extensive radiofrequency (RF) ablation in the left atrium (LA) for persistent AF. We report a retrospective assessment of the efficiency of program implementation.

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