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Anxilor (Lorazepam)
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Anxilor

Anxilor, an antianxiety agent, has the chemical formula, 7-chloro-5-(o-chlorophenyl)-1,3- dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one. It is a nearly white powder almost insoluble in water. Each Anxilor tablet, to be taken orally, contains 0.5 mg, 1 mg, or 2 mg of Anxilor. The inactive ingredients present are lactose monohydrate, magnesium stearate, microcrystalline cellulose, and polacrilin potassium.

Other names for this medication:
Almazine, Anxilor, Anxionil, Anxipose, Atipam, Biokalm, Biolar, Calmese, Dulozep, Larosh, Larpose, Lopam, Lopez, Loracalm, Lorakar, Loralite, Lorazam, Lorazepam, Lorazine, Loricon, Loripam, Lorivan, Lorpam, Lorvin, Lotweet, Nexlor, Norpose, Olraz, Trapex, Urpam, Zelor, Zepatrac, Zepnap

Similar Products:
Keflex, Skelaxin, Amoxil, Duricef, Klonopin, Dramamine, Sustiva, Cholical, Tribet, Fultop, Trandy, Kefnir, Etomax, Etavone,

Also known as: Lorazepam

Description

Anxilor, a benzodiazepine with antianxiety, sedative, and anticonvulsant effects, is intended for the intramuscular or intravenous routes of administration.

Anxilor is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Anxilor affects chemicals in the brain that may become unbalanced and cause anxiety. Anxilor is used to treat anxiety disorders.

Anxilor may be habit-forming and should be used only by the person it was prescribed for. Anxilor should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Dosage

Lorazepam is injected into a muscle or vein by a healthcare provider.

You may need to receive only one dose of lorazepam if your condition improves after the injection.

After the injection, you will be watched to make sure the medicine is working and does not cause harmful side effects.

Lorazepam injection is for single or occasional use. Ongoing use may be habit-forming or cause long-lasting withdrawal symptoms when you stop using the medicine.

Detailed Anxilor dosage information

Overdose

In cases of a suspected Anxilor overdose, it is important to establish whether the patient is a regular user of Anxilor or other benzodiazepines, since regular use causes tolerance to develop. Also, one must ascertain whether other substances were also ingested.

Signs of overdose range through mental confusion, dysarthria, paradoxical reactions, drowsiness, hypotonia, ataxia, hypotension, hypnotic state, coma, cardiovascular depression, respiratory depression, and death.

Early management of alert patients includes emetics, gastric lavage, and activated charcoal. Otherwise, management is by observation, including of vital signs, support and, only if necessary, considering the hazards of doing so, giving intravenous flumazenil.

Patients are ideally nursed in a kind, nonfrustrating environment, since, when given or taken in high doses, benzodiazepines are more likely to cause paradoxical reactions. If shown sympathy, even quite crudely feigned, patients may respond solicitously, but they may respond with disproportionate aggression to frustrating cues. Opportunistic counseling has limited value here, as the patient is unlikely to recall this later, owing to drug-induced anterograde amnesia.

Storage

Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Anxilor is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Anxilor are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Anxilor can interact with several other medications. It can also interact with certain supplements and foods.

Different interactions can cause different effects. For instance, some can interfere with how well a drug works, while others can cause increased side effects.

Anxilor and other medications

Below is a list of medications that can interact with Anxilor. This list doesn’t contain all drugs that may interact with Anxilor.

Before taking Anxilor, be sure to tell your doctor and pharmacist about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Opioids

Taking opioids with Anxilor can cause dangerous side effects. These include excessive drowsiness, breathing problems, respiratory failure, and coma.

Examples of these drugs include:

  • morphine (Astramorph PF, Kadian, MS Contin, and others)
  • oxycodone (Percocet, Roxicet, Oxycontin, and others)
  • hydrocodone (Zohydro ER, Hysingla ER)
  • methadone (Dolophine, Methadose)
  • fentanyl (Abstral, Duragesic, and others)
Opioids should only be used with Anxilor when there are no other treatment alternatives.

Sedative drugs

Taking sedative drugs with Anxilor can cause excessive drowsiness and breathing problems. Examples of sedative drugs include:

  • anticonvulsant medications such as carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), phenytoin (Dilantin, Phenytek), and topiramate (Qudexy XR, Topamax, Trokendi XR)
  • antihistamines such as diphenhydramine (Benadryl), cetirizine (Zyrtec), chlorpheniramine (Chlor-Trimeton and others), and doxylamine (Unisom and others) — also found in over-the-counter and combination products
  • antipsychotic drugs such as clozapine (Clozaril, Fazaclo ODT), haloperidol (Haldol), quetiapine (Seroquel), and risperidone (Risperdal)
  • anxiety drugs such as buspirone (Buspar)
  • barbiturates such as phenobarbital
  • other benzodiazepines such as alprazolam (Xanax), clonazepam (Klonopin), diazepam (Valium), and midazolam
Probenecid

Taking Anxilor with probenecid, a drug that can be used to treat gout, can increase the levels of Anxilor in your body. This can increase your risk of Anxilor side effects. For people who take probenecid and Anxilor together, the Anxilor dosage needs to be reduced by half.

Valproic acid

Taking Anxilor with valproic acid (Depakene, Depakote), a drug used to treat seizures and other conditions, can increase the levels of Anxilor in your body. This can increase your risk of Anxilor side effects.

For people who take valproic acid and Anxilor together, the Anxilor dosage needs to be reduced by half.

Anxilor and Zoloft

Zoloft (sertraline) can make some people feel tired or drowsy. Anxilor can also cause drowsiness. Taking these medications together may cause you to feel even more tired or drowsy.

Anxilor and Ambien

Anxilor and Ambien (zolpidem) shouldn’t be taken together. Both medications are used to help promote sleep. If taken together, they can cause excessive sleepiness and sedation.

Taking this combination of medications can also increase the risk of odd behaviors such as sleep-driving (trying to drive while asleep).

Anxilor and Tylenol

There are no known interactions between Anxilor and Tylenol (acetaminophen).

Anxilor and herbs and supplements

Taking Anxilor with herbs or supplements that have sedative effects can cause excessive drowsiness and breathing problems. Examples of sedative herbs and supplements that can cause these effects include:

  • chamomile
  • kava
  • lavender
  • melatonin
  • valerian
Anxilor and marijuana

Marijuana shouldn’t be used with Anxilor. Using marijuana with Anxilor can cause excessive drowsiness or sedation.

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The anti-apoptosis protein, survivin, mediates gastric epithelial cell cytoprotection against ethanol-induced injury via activation of the p34(cdc2) cyclin-dependent kinase. In addition, the anxiolytic effect of diazepam was abrogated in tg mice. The ubiquitinylating process is important for the control of protein degradation by the 26S proteasome. Twenty-two fetuses were diagnosed in utero with posterior urethral valves due to the presence of persistent megacystis and hydronephrosis. This paper describes a nasal surgical simulator that we have designed and implemented to run on the WWW using VRML and Java.

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Relational aggression explained a small but significant amount of unique variance in impairment, controlling for ODD and CD symptoms. This is a summary of the current knowledge of sensory receptors in skin of the bill of the platypus, Ornithorhynchus anatinus, and the snout of the echidna, Tachyglossus aculeatus. This article reports two cases of immature permanent mandibular molars with clinical signs of pulp vitality and radiographic images of periapical bone rarefaction, which were treated with calcium hydroxide pulpotomy. In the past, silicone oil has been used mostly as a last resort following failed primary surgery. The methods developed have been implemented in the MBESS package in R so that they can be easily applied by researchers. We found that cancer-specific selection pressure is quite different from the selection pressure at the species and population levels. Narrow size range of AgNPs (5-40 nm) observed in HR-TEM analysis.

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An 80-year-old male patient underwent emergency surgery for an incarcerated right inguinal hernia found to contain a gangrenous appendix. In this review, we elucidate how adenoviral vector modifications alter the IFN and innate inflammatory pathway response and propose future targets with clinically-translational relevance. In comparison with the genes in the normal brain tissue, 6 down-regulated and 35 up-regulated genes in the medulloblastomas were revealed by means of the microarrays and autoradiography, and were verified by reverse transcriptase-PCR. The third group of subjects was identified by the high level of activation of the right hemisphere in the background activity and during the first presentations of functional loads, and by activation of the right hemisphere at the final stages. Thus the AR film with improved mechanical property is desirable in an industrial application.

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All three methods rely on the sensitivity to destruction by light of the pathogen being significantly lower than the sensitivity of the surrounding host tissues (favorable therapeutic ratio). We also examined the effect of supplementing the biofilter with yeast extract (YE). To meet the growing demand for objective outcomes measurement during treatment of chronic pain, we developed an instrument to track outcomes of individual patients. T-regulatory cells and Th1/Th17 responses were assessed by flow cytometry and real-time polymerase chain reaction more than 4 years after transplantation in 10 kidney recipients treated with alemtuzumab induction. DXR was found to induce significant ECG alterations (Qat and Sat prolongation) and typical morphologic lesions in the left ventricle. A polymorphism in the poliovirus receptor gene differs in motor neuron disease.

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Ovine adenovirus OAV287 (OAV) is phylogenetically and serotypically distinct from human Ad5. By defining the ROIs for neurosurgical video, this method produces a smooth and convex emphasis region within which surgical procedures are performed. During the phase of radiation pneumonitis, BM activation was revealed, according to an increase in the spreading index, DNA relaxation, enhanced phagocytic capacity of isologous thymocytes. In contrast, we found that the middle region of the PrP TM domain significantly reduces the ability of the chain to invert its orientation in the translocon. Ultrasonography can detect structural muscle changes caused by neuromuscular disease, but it has not yet been applied to facial nerve diseases.

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Collectively, our clinical and in vitro data indicate that the status of caveolin-1 expression may be one of causative factors for the invasion and poor prognosis in HCC. In fact, the GFAP levels in the cerebrospinal fluid during acute exacerbation of NMO are remarkably elevated, while the values in MS are not different from those in controls. For the majority of isolates that were analyzed, a high degree of polymorphism suggested different sources of infection. Prophylaxis with unfractionated heparin (UFH) has been proven to reduce rates of venous thromboembolism (VTE) in hospitalized medical patients. Molecular imaging is the visualization, characterization, and measurement of biologic processes at the molecular and cellular levels in humans and other living systems (1). Activities of telithromycin against 13,874 Streptococcus pneumoniae isolates collected between 1999 and 2003.

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Preincubation with AX rendered target cells susceptible to NK cell-mediated lysis. In a rabbit model, rib perichondrium was used to repair defects created in the femoral condyle. Moreover these interventions lead to significant life span extension, provide better body fitness and prevent development of multiple age-related diseases. The low incidence is undoubtedly due to the strict inclusion criteria in the present study, i.e. A principal issue is how particle structure and loading affects the magnetostriction of these materials. Performing breast self-examination (BSE) in an accurate manner can assist a woman in detecting any abnormalities in her breasts, which may mark the onset of potential disease. In addition, the production of IL-2 was inhibited by the opioid treatment, but this might not be the only mechanism of action. The association of NSAIDs with specific lower GI adverse events and long-term complications requires further investigation. The aim of this study was to investigate if the method of PTP computation is affected by the breathing pattern when mechanical load and inspiratory time per minute are constant. Children with respirator-dependent quadriplegia because of C-2 spinal cord injuries are now surviving the acute stages of their injury.

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We examined the effect of resveratrol on the expression and activation of Akt/protein kinase B and its impact on melanoma cell migration and invasiveness. Therapeutic maintenance level of methotrexate in rheumatoid arthritis. During gasping the phrenic nerve fires with an abrupt onset and rises rapidly to maximal neural activity with a decrementing decline. There was no significant difference in the number of larvae recovered from eCry3.1Ab-expressing and isoline maize for the selected colony, whereas this difference was significant for the control colony. To examine the influence of deep brain stimulation on hippocampal neurogenesis in an adult rodent model. Application of this method allowed for detection of a 100-fold increase in plasma Abeta1-40 following treatment of Tg2576 mice or wild type littermate control mice with Abeta40-specific monoclonal antibody 9TL. The paired t-test test was used for statistical analyses with SPSS software version 20 (SPSS Inc., Chicago, IL, USA). The storage modulus, which is a mechanical factor, was reduced in CKD model rats compared with controls that underwent thyroparathyroidectomy alone (TPTx).

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New directions in perioperative management for pediatric solid organ transplantation. The intraoperative gamma probe technique enables the surgeon to focus the search, provides instant feedback regarding the progress of the operation, reduces surgical trauma and complications, and yields better cosmetic results. We also provide analytical estimates for the stationary pattern wavelength and mean growth velocity. However, the precise mechanisms by which these factors interact to form transcriptional networks, as periactin syrup dose well as the identity of the genes downstream of these regulatory cascades, remain largely unknown. Effect of metal ions on some pharmacologically relevant interactions involving fluoroquinolone antibiotics. Neighbourhood ethnic diversity mitigated the negative impact of ESL status on school readiness for both domains. Electron microscopic demonstration of sodium ions in the macula densa of the middle part of the rat kidney. Bragg spectroscopy enables us to investigate the excitation spectrum in different regimes. Up-regulation of nicotinic receptors by nicotine varies with receptor subtype.

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