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An advanced statistical model is suggested that is designed to estimate the twinning fraction in merohedrally (or pseudo-merohedrally) twinned crystals. Activation of the beta-globin locus control region precedes commitment to the erythroid lineage. The content of GSH in myocytes also decreased after manganese exposure. By using PLS we investigated the relations between the rheological properties of a gel and the parameters defining the cohesiveness, as measured with the texture analyser used for the mucoadhesion measurements. In the mouse model, the blood PCR was compared with results obtained by PCR on bronchoalveolar lavage fluid (BALF) samples, cultures of blood and BALF and detection of Legionella urinary antigen.
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Some problems of spontaneous and induced mutagenesis in mammals and man. HepG2X cells expressing URG7 and HepG2 cells overexpressing URG7 in the absence of HBxAg were resistant to TNFalpha killing compared with HepG2CAT cells. These studies indicate that both deltaNp63alpha and TAp63alpha can negatively regulate keratinocyte survival. The primary function of neuronal gap junctions, therefore, might be to coordinate biochemical activity, rather than to act as purely electrical synapses. In rat hepatocytes CAR was induced by WY14643, a PPARalpha-agonist. Mutant Chinese hamster ovarian (CHO) cells with a resistance to 7-10(-7) and 8-10(-7) M cycloheximide (CHM) were induced at mutation rates of 1.9-5.2-10(-3) and 1.6-1.8-10(-3) respectively after treatment with N-nitrosomethylurea (NMU) at 100 mug/ml.
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The experimental data obtained in this work suggest that possible causes are the reduction of nitrogen dioxide and nitrate by radical species formed on photooxidation of the organic compounds. In the present study, the entire pre-S domain was mapped for infectivity determinants, following a reverse-genetics approach and using in vitro infection assays with hepatitis delta virus (HDV) or HBV particles. To investigate the role played by these proteins in adhesion, the proteins were isolated from the adhesive mucus of different molluscs and added to commercial polymer solutions. Exposure of pregnant mice to an air pollutant aerosol increases asthma susceptibility in offspring. Both within-modality (MEG-MEG) and between-modality studies (sEMG-MEG) were conducted.
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Laparoscopy for gynaecological procedures is minimally invasive and is mostly performed as a daycase. Previous studies have suggested that clots with thinner fiber diameter lyse at slower rates than clots with thicker fiber diameter. Agrimoniin induced IL-1 beta secretion dose- and time-dependently. The utility of evoked response audiometry from the inferior colliculus for quickly assessing auditory thresholds in the guinea pig is discussed. It is discussed whether restriction during natural transformation acts at presynaptic or postsynaptic stages of transforming DNA. Forgoing adjuvant chemotherapy should be considered in patients with stage II colon cancer who are negative for MSI and LI. Emphysema and ventilatory disorders: studies at rest and during work. However, there is a dearth of case reports in the literature to substantiate this belief. Relaxing incisions were found to be a safe and effective method for reducing postoperative astigmatism and may improve visual acuity. Flow-mediated dilation (FMD) of the brachial artery as an indicator of vascular function significantly increased, while carotid artery intima-media thickness and vascular wall stiffness did not progress under treatment.
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About one-quarter of all procedures performed on females were obstetrical. Glutathione reductase significantly increased from 49.5 U/L in BD1 to 57 in HD and decreased to 49.2 in BD2. Comparison of intraosseous and extraosseous alveolar distraction osteogenesis. Many of the current methods for constructing shRNA expression vectors require cumbersome and time-consuming procedures for identification of the desired recombinants. Finally, thromboembolic events during chemotherapy may predict vascular events in the long term, either as a sign of irreversible damage or as a sign that the patients involved are vulnerable to vascular damage in general. Importantly, similar results were obtained with a constitutively active GR.
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Since SP-D has a potent anti-inflammatory function, this mechanism may be part of a negative feedback loop providing a regulatory link between adaptive and innate immunity during allergic inflammation. Results of conventional treatment of severe congestive heart failure with vasodilators. All three patients responded well and now are without evidence of tumor, 37, 30, and 36 months after BCNU was stopped. Once incorporated to these levels, many of these analogues induce the synthesis of a regulatory protein, antizyme, which inhibits both polyamine synthesis and the transporter they used to enter the cell. The molecular pathology underlying Kindler syndrome has recently been shown to involve loss-of-function mutations in a novel gene, KIND1, encoding kindlin-1.
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These contrasting situations evoked by NO provide insights into basic chemical reactions, biochemical signal transduction pathways with broad implications for medicine. A small amount of data on the induction of sex-chromosome aneuploidy by 200 rad in golden hamsters suggested that the hamster might be as sensitive as the mouse. General anesthesia with single-lung ventilation and bimanual lung palpation is considered mandatory in pulmonary metastasectomy. The determination of the configuration of a protein in three-dimensional (3D) space constitutes one of the major challenges in molecular biology research today. This stereoselective, transition metal-catalyzed, C-C bond-forming reaction could serve as a key step for the construction of the all-anti and syn-anti stereotriad building blocks 20, 21, and 31, which should be well-suited for target-oriented polypropionate synthesis.
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Studies were performed in 6 healthy, male volunteers to explore the effect of a work load on the blood concentrations of catecholamines in relation to pulse rate and blood pressure and the blood levels of pancreatic glucagon, insulin, growth hormone, glucose and glycerol. MG-160 is an intrinsic type I cysteine-rich membrane sialoglycoprotein that resides in the medial cisternae of the Golgi apparatus, highly homologous to CFR, chicken fibroblast growth factor receptor, and ESL-1, E-selectin ligand. On each testing day, participants completed experiential (real-world money in real time) and hypothetical discounting tasks. Alternative 1-(13)C glucose infusion protocols for clinical (13)C MRS examinations of the brain. Further research is in progress to evaluate this treatment modality in a larger number of patients.