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Anastrocare (Anastrozole)
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Anastrocare

Anastrocare lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body. Anastrocare is used to treat breast cancer in postmenopausal women. Anastrocare is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox).

Other names for this medication:
Altraz, Altrol, Anabrez, Anastrocare, Anastrozole, Anatero, Anazol, Armilon, Armotraz, Femistra, Femitraz, Qubol, Redest, Rimidex, Stazonex, Xenosoul

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Also known as: Anastrozole

Description

Anastrocare (anastrozole) lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.

Anastrocare is used to treat breast cancer in postmenopausal women.

Anastrocare is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox).

Dosage

The following information describes Anastrocare dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Drug forms and strengths

Anastrocare comes as 1-mg tablets that are taken by mouth.

Dosage for breast cancer

The usual dosage of Anastrocare for breast cancer is one tablet taken once a day. It’s best to take your dose at the same time each day.

What if I miss a dose?

If you forget to take a dose of Anastrocare, take the missed dose as soon as you remember. However, if it’s almost time for your next dose, just skip the missed dose and take your next dose as usual. Don’t take two doses together to make up for a missed dose.

To help make sure that you don’t miss a dose, try setting a reminder on your phone. A medication timer may be useful, too.

Will I need to use this drug long term?

Anastrocare is meant to be used as a long-term treatment for breast cancer. If you and your doctor determine that Anastrocare is safe and effective for you, you’ll likely take it long term.

The length of time that you’ll take this drug depends on the type of cancer you’re using it to treat. Below we describe the typical length of time that Anastrocare is given. But to know for sure how long you should take Anastrocare, talk with your doctor.

For advanced breast cancer

If you’re taking Anastrocare to treat advanced breast cancer, you’ll usually take the drug for as long as your doctor feels this treatment is right for you. (With advanced breast cancer, the cancer has either spread to nearby areas or lymph nodes, called locally advanced breast cancer, or spread to other parts of your body, called metastatic breast cancer.)

For early breast cancer

If you’re taking Anastrocare as adjuvant treatment of early breast cancer, you’ll usually take the drug for at least 5 years. Adjuvant treatment is used to lower the risk of your breast cancer coming back or spreading after it’s already been treated with surgery. (With early breast cancer, the cancer hasn’t spread out of either your breast or the lymph nodes in your armpit.)

It’s not currently known if Anastrocare should be continued after these 5 years. And if so, it’s not known for how long after the first 5 years it should be taken.

Some studies found that breast cancer is less likely to come back if an aromatase inhibitor is taken for an additional 5 years after the first 5 years of adjuvant therapy. (Aromatase inhibitors are a class of medications.) With this approach to treatment, the drug would be taken for a total of 10 years. However, other studies didn’t show a benefit for extending the treatment beyond 5 the usual years.

In addition, one recent study found that taking Anastrocare for a total of 10 years didn’t provide any more benefit than taking it for a total of 7 years.

How long you take Anastrocare for early breast cancer will depend on how likely your breast cancer is to come back. It will also depend on your risk of side effects from treatment.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Anastrocare are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Anastrocare can interact with several other medications.

Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe.

Anastrocare and other medications

Below are lists of medications that can interact with Anastrocare. These lists do not contain all the drugs that may interact with Anastrocare.

Before taking Anastrocare, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Anastrocare and tamoxifen

Like Anastrocare, tamoxifen is a hormone therapy that’s used to treat breast cancer. But taking tamoxifen with Anastrocare can lower the amount of Anastrocare in your body. This can make Anastrocare less effective for you.

Because of this interaction, you shouldn’t take tamoxifen with Anastrocare. However, if recommended by your doctor, it’s fine to take Anastrocare after you’ve finished taking tamoxifen.

Anastrocare and drugs that contain estrogen

Taking Anastrocare with drugs that contain estrogen could make Anastrocare less effective for you. Because of this, you shouldn’t take these types of drugs while you’re using Anastrocare.

Examples of drugs that contain estrogen include:

  • hormone replacement therapy (HRT)
  • vaginal estrogen products, such as creams and tablets
  • birth control medications, such as pills, patches, and vaginal rings
If you have questions about using medications that contain estrogen with Anastrocare, talk with your doctor.

Anastrocare and herbs and supplements

There aren’t any herbs or supplements that have been specifically reported to interact with Anastrocare. However, you should still check with your doctor or pharmacist before using any of these products while taking Anastrocare.

For example, it’s possible that supplements such as red clover or wild yam could make Anastrocare less effective. (These supplements are used by some women to reduce menopausal symptoms, such as hot flashes.)

This interaction is possible because these supplements contain phytoestrogens, which are weak estrogen-like substances found in certain plants. There isn’t enough information available to say for sure whether taking phytoestrogens can affect your breast cancer treatment or not.

Be sure to talk with your doctor before taking any herbs or supplements with Anastrocare.

Anastrocare and foods

There aren’t any foods that are known to interact with Anastrocare. Talk with your doctor to find out if there are any foods you should avoid during Anastrocare treatment.

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We applied a phylogenetic ecology approach in the Kingdom Euryarchaeota (Archaea) to gain insight into the environmental distribution and evolutionary history of one of the most ubiquitous and largely unknown microbial groups. In addition, total dollars spent each month on television advertising at the national and local levels for atorvastatin, pravastatin, and simvastatin were obtained. Bird arrival at breeding sites is highly correlated with nautical dusk for moonless or slightly moonlit nightfalls and correlated with moonset when the moon is visible. Allergic contact dermatitis to pentylene glycol in a cosmetic cream. This process is initiated by factors, termed the particulate matrix, that are secreted by the myocardium. Here, we explored this relationship in a large contemporary Middle Eastern ACS registry: the second Gulf Registry of Acute Coronary Events (Gulf RACE-2). This technique may improve the success rate of wire crossing and successful CTO intervention. On the other hand, jmj mutant mice with a BALB/c background die around E14.5, suggesting that genetic background modifies hyperproliferation in the heart and timing of lethality. The presence of mucoid pseudomonas is not pathognomonic for cystic fibrosis. Increasing rates of Down syndrome among newborns in Chile from 1972 to 2005.

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Association of phosphoinositide-specific phospholipase Cgamma1 with intermediate filaments in A-431 cells. Expression studies suggest a dominant-negative effect within the AChR pentamer, severely compromising receptor function. The potential replication of somatic coliphages in the environment has been considered a drawback for their use as viral indicators, although the extent to which this affects their numbers in environmental samples has not been assessed. Regression of vestigial tooth buds results in the formation of the toothless diastema, a unique feature of the mouse dentition. However, before stepping into the limelight, next-generation sequencing had to overcome the inertia of a field that relied on Sanger-sequencing for 30 years. Levels and patterns of daily physical activity and sedentary behavior measured objectively in older care home residents in the United Kingdom. Congenital mesoblastic nephroma is a relatively rare renal tumor predominantly of childhood. The dynamic light scattering measurements suggest that the A form transforms completely into larger size aggregates at an early stage during the aggregation process.

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Preoperative selection of the patients with regard to residual sphincter function and a special attention on better sling fixation may increase RTS efficacy. The findings indicate that a two-scale solution is a stable and statistically supported framework for interpreting data obtained by means of the MMSE. The chromosome complement of Sorex granarius--the ancestral karyotype of the common shrew (Sorex drug interactions with prograf araneus)?. The high temperature (28 degrees C) produced significant increases in IRG in both short and long-term experiments. Causes of death, including the frequency in which ILD was recorded on death certificates were examined. Acute and chronic histological changes of the small bowel secondary to C. Epilepsy is a complex medical disorder and the rehabilitation process must address many aspects. Evidence restricted to the African regions suggests that LNS may be slightly more effective than specially formulated fortified foods or nutritional counselling in recovery from MAM, lowering the risk of deterioration into SAM, and improving weight gain with little impact on mortality or default rate. The median survival was 15 weeks (range 1-65 weeks) from the start of HH treatment. Other safety pharmacology topics detailed in this unit are the timing of such studies, ethical and animal welfare issues, and statistical evaluation.

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The web resource is based on a relational database, containing data of plants protease inhibitors publicly accessible, and a graphical user interface providing all the necessary browsing tools, including a data exporting function. Extramedullary hematopoiesis should also be considered as a cause of pulmonary hemorrhage, especially in the setting of myelofibrosis. Uncoupling sweet taste and calories: comparison of the effects of glucose and three intense sweeteners on hunger and food intake. Possible side effects that might arise from targeting NOX2 are discussed, including the possibility that such inhibition will contribute to increased infections and/or autoimmune disorders. Between May 1991 and December 2002, 15 men and 5 women (mean age, 42 years) with histologically proven malignant fibrous histiocytoma of bone underwent treatment involving limb salvage surgery complimented by a customised mega prosthesis. Bcl-x(L) expression was found to be increased in the pulmonary artery of chronic hypoxia-treated rats with pulmonary vascular remodeling. The physicochemical properties of pH allow the signal to be fast, and affect multiple regulatory levels simultaneously.

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Furthermore, the retinoblastoma protein (pRb) was required for the ubiquitination of topoisomerase IIalpha by BRCA1. Repeat surgery in 6 patients included complete cystectomy and urinary diversion in 2 who had positive margins and recurrence after radiotherapy, urethrectomy and continent diversion for positive margins in 1, partial cystectomy and continent diversion in 1, and radical prostatectomy, partial cystectomy and continent diversion in 1 with stage IV disease who had local recurrence. One advantage of 68Ga-DOTA-peptides PET is to select patients with well-differentiated and inoperable NENs for peptide receptor radionuclide therapy (PRRT). The long-term results of removal of staghorn calculi by extended pyelolithotomy without cooling or renal artery occlusion. Functional study showed that distinct biological processes were enriched in each cluster, which seems to reflect different aspect of tumor progression or oncogenesis among distinct patient groups. Urine samples were analyzed by GC-MS and LC-MS in combination with pattern recognition techniques, e.g. Monocyte adherence, penetration, migration, and long term survival can be studied under these conditions. With this rapid system, it has been found that pertussis, or its histamine-sensitizing factor, inhibited the host mononuclear cell component of the pervascular lesions. In contrast 4-days of pre-exposure to carbon dust increased the number of antibody-forming cells in the mediastinal lymph nodes. The further penetration of information technology into health care is discussed and it is concluded that information systems have already become a vital component, not only for the logistics of the health care institution but also for the rendering of care and cure.

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