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Amlodilan (Amlodipine)
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Amlodilan

Amlodilan works by causing some of your blood vessels to relax and widen. This lowers your blood pressure. It also reduces the force and the rate of your heartbeat, and this helps to prevent angina chest pain. It does these things by blocking the amount of calcium that goes into the 'smooth' muscle cells in the walls of your arteries and in your heart. Calcium is needed for muscles to contract, so reducing the amount of calcium causes the muscle cells to relax.

Other names for this medication:
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Also known as: Amlodipine

Description

Amlodilan (amlodipine) is a calcium channel blocker that dilates (widens) blood vessels and improves blood flow.

Amlodilan is used to treat chest pain (angina) and other conditions caused by coronary artery disease.

Amlodilan is also used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.

Amlodipine is for use in adults and children who are at least 6 years old.

Dosage

You should take it by mouth. It is better to take Amlodilan once a day at the same time. Amlodilan treats angina and hypertension diseases and can be used both by adults and by children. Children of 6-17 years: Starting dosage is 2.5-5 mg. People with vasospastic angina or coronary artery disease: Starting dosage is 5-10 mg. Elderly people, people with hepatic: Starting dosage is 2.5 mg. If you want to achieve most effective results do not stop taking Amlodilan suddenly.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include rapid heartbeats, redness or warmth in your arms or legs, or fainting.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Amlodilan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Amlodilan if you are allergic to amlodipine.

To make sure Amlodilan is safe for you, tell your doctor if you have ever had:

liver disease; or a heart valve problem called aortic stenosis.

Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether Amlodilan will harm an unborn baby. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating hypertension may outweigh any risks to the baby.

Amlodipine can pass into breast milk, but effects on the nursing baby are not known. Tell your doctor if you are breastfeeding.

Amlodilan is not approved for use by anyone younger than 6 years old.

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The acute neurotoxicity and effects upon cholinergic axons of intracerebrally injected beta-amyloid in the rat brain. Here, we identify two heterotrimeric GTP-binding protein (G protein)-coupled receptors (GPCRs) that mediate dauer formation in response to a subset of dauer pheromone components. Research self-efficacy within each group also significantly increased following the short-term research training program, but cross-group comparisons were not significant. Treatment of elderly psychiatric inpatients with antipsychotics did not increase their risk of adverse medical outcomes. This article provides critical care nurses with an understanding of the etiology of AF, risk factors associated with the development of it, and current treatment options for this dysrhythmia. In this note, we show that expectancies generated by predictable stimulus motion trajectories can also produce smooth deceleration, reversal of direction, and subsequent acceleration in these movements, and explore the limits of the predictive component of the SEM control system quantitatively. In acute stroke patients, there is a need for noninvasive measurement to monitor blood flow-based therapies. Electrophysiologic assessment of respiratory activity in the phrenic nerves was conducted in C2 hemisected rats 4 months after hemisection under standardized conditions.

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Both monoclonals produced punctate nuclear and diffuse cytoplasmic staining in human and mouse cell lines. Data were collected on standardized forms and included the numbers of postal employees screened and offered antibiotic prophylaxis, as well as the numbers of patients seen per worker hour by various medical professionals. Two competing theories to explain this comorbidity are (i) the phenotypic causation (gateway) model and (ii) the correlated liabilities model. The upper bottom made of porous titanium served as a hydrophilic porous membrane stabilizing aquatic potential in the root-inhabited zone at a given level. The luminal epithelium of the porcine oviduct is composed of ciliated cells and secretory cells, but it is assumed for several species that under the control of steroid hormones secretory cells are able to be transformed into ciliated cells. This is the first report of arthropods associated with carrion in Venezuela, using laboratory bred rats (Rattus norvegicus). Biological effects of exposure to high frequency electromagnetics on rabbits and guinea pigs.

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Evaluation generally begins after 12 months, but it can be initiated earlier if infertility is suspected based on history or if the female partner is older than 35 years. The PLGA skeleton facilitates the formation of the hybrid sheets into desired shapes, and the collagen microsponges in the pores of the PLGA sheet promote cell adhesion and uniform cell distribution throughout the sheet. For prosthetic dentistry, how one uses individual patient findings to arrive at possible treatment alternatives was clarified in greater detail. The need for better training of trauma teams and especially team leaders requires further investigation and action. High-energy extracorporeal shock wave therapy as a treatment for chronic noninsertional Achilles tendinopathy. By linking the two databases we have closed the loop in our documentation. The age-specific incidence data from most human carcinomas, including those of the colon, lung, prostate, and breast were consistent with the parallel route hypothesis. A 79-year-old male with a Bricker loop and chronic renal failure was admitted to hospital because progressive dyspnoea. An analytical description of the effects of spectral hole burning on the optical properties of active semiconductor materials is developed for fields that are slow compared to intraband relaxation times. Problems of extracorporeal circulation with the artificial heart-lung system.

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In this post 9/11 era, development of law enforcement-specific medical training appears appropriate. mansoni, but is less effective against ACHE of mammalian origin. Efforts to promote AED adherence may lead to cost savings for managed care systems. Determinants of continuous positive airway pressure compliance in a group of Greek patients with obstructive sleep apnea. Dengue virus is sensed in mammalian cells by Toll-like receptors and DExD/H box RNA helicases, triggering a Type 1 interferon response. The youngsters are clearly conditioned by the society where they live, though they may feel apart. Determination of tumoral stage following Tos and Thomsen image criteria. Here we show that KN93, an inhibitor of CaM-dependent kinases (CaMKs), also inhibits the phosphorylation of IkappaB.

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An effort to detect this protein in enterocystoplasty specimens also showed a negative pattern. The role of signaling pathways in osteoblast gravity perception. Comparative evaluation of a chemiluminescent DNA probe and an exoantigen test for rapid identification of Histoplasma capsulatum. In each case, the estimation was quite accurate even if the convergence, driven by the dilution rate, was slow (from 15 to 60 days). Further regulatory implications of the NC2 heterodimer structure are discussed. Apart from these proteins, a very large number of antifungal proteins active on the fungal cell wall, on enzymes of the cell wall synthesis machinery, the plasma membrane and on intracellular targets have been characterised. Abstracts accepted by the Annual BAPS Congress meetings between 1996 and 2000 were examined in collaboration with a senior health services researcher. Impairment of airway mucociliary transport by Pseudomonas aeruginosa products. The comparison of food patterns of the elder people in 1990 and 2006. This study was conducted to evaluate, using soil columns, the mobilization and redistribution of heavy metals (Zn, Cd, and Pb) among different soil fractions by soluble organic ligands within poultry litter.

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For the first time, we demonstrate that environmentally realistic levels of UV-B radiation can induce ocular damage in barnacle larvae, thereby impairing the phototactic behavior of naupliar larvae and reducing settlement success of cypris larvae. Response and remission rates in Chinese patients with bipolar mania treated for 4 weeks with either quetiapine or lithium: a randomized and double-blind study. Moyamoya syndrome is a potentially serious complication of cranial irradiation in children, particularly for those patients with tumors in close proximity to the circle of Willis, such as optic pathway glioma. A molecular clock was calibrated considering that the split between Iberian and North African Blanus was due to the re-opening of the Betic Strait in the Upper Tortonian (8-9 million years ago). Agenesis of the corpus callosum: genetic, developmental and functional aspects of connectivity. The immunogenicity, short half-life and inability to recruit host effector functions such as antibody-dependent cell-mediated cytotoxicity associated with the rodent monoclonal antibodies limit their clinical use. Preparation of proteoglycans for N-terminal and internal amino acid sequence analysis.

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The thigh and hip manifestations can obscure the primary intra-abdominal process either due to the obvious emphysema or to the obtunded abdominal signs secondary to associated neuropathy. Both MVB12 depletion and overexpression inhibit HIV-1 infectivity and induce unusual viral assembly defects, including aberrant virion morphologies and altered viral Gag protein processing. This difference was assumed to be mainly due to more efficient CO2 elimination through lung ventilation in hyperventilation as compared with CO2 accumulation from tissue metabolism in hypoventilation. When cells became confluent, the steady-state uptake of NMD by rBMEC with or without baicalin and berberine was measured. Using street outreach, 443 African-American crack users were recruited in North Carolina and randomly assigned to either the pretreatment intervention or control group. With sufficient computer speed these techniques can be used for continuous monitoring of the position of instruments within the cranial vault. Influence of environmental gradients on the abundance and distribution of Mycobacterium spp. Endogenous erythropoietin and recombinant human erythropoietin (rHu-EPO) are similar with respect to their biological and chemical properties except for some microheterogeneities in their 4 carbohydrate chains.

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In the suprachiasmatic nucleus (SCN), hnRNP U immunoreactivity (ir) changed in a robust circadian pattern as it showed a peak at late nighttime in both light/dark and constant dark conditions. Pharyngeal pH monitoring is a diagnostic tool used to identify Gastroesophageal reflux disease (GERD) as an etiology of respiratory symptoms. A recombinant full-length genome plasmid (pCTN-GFP) contained the full-length genome of the CTN strain expect for psi gene which was replaced by GFP gene was then constructed using restriction enzyme cleavage and ligation in vitro. The incidence of MDS is more in older age groups and frequent chromosome abnormalities reported to be monosomies 5 and 7. This is the first case report of a human immunodeficiency virus-negative individual, a non-contact lens wearer, with microsporidia infection. GABA-ir neurons, fibres and nerve terminals were scattered in all parts of the VN. FasL induces early apoptosis of activated T cells by interfering with anti-apoptotic signals. injected with either 0.5 mL of AdT beta-ExR (1.0 x 10(9) plaque-forming units/mL) or AdLacZ (1.0 x 10(9) plaque-forming units/mL), a control adenovirus expressing bacterial beta-galactosidase, or saline, then 3 days later they received 4-MV X-ray irradiation of 30 Gy in a single fraction to the right lung. Ultrastructural parameters of fertile cryopreserved human sperm. These factors will be used as a starting point for organizational change to enhance infant outcomes in the NICU.

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The construction of collagen fiber scaffolds, which provide the structural integrity of the extracellular matrix of connective tissues and basement membranes, is initiated by a complex mechanism of protein-folding, whereby pro-collagen alpha-chains are assembled into triple-helical procollagen molecules. Though anaphylactic and anaphylactoid reactions may be clinically indistinguishable, they involve different mechanisms. This suggests that Abeta increases the sensitivity of both the NMDA receptor and the kainate receptor. Although some features of the initial computed tomogram had highly significant associations with the presence of a cardiac source of embolism, the predictive value of these features for an embolic source was low. These suppressions were significant at 0.5 mM with both amplitude and frequency. Nursing is in an excellent position to be a leader in integrating these therapies into the Western biomedical health model and in continuing the research that will provide a better scientific base for the use of complementary therapies. Thereafter, the autophagic vacuoles increased in number and size with time. Non-sequential ray-tracing (OptiCAD) was applied to an anatomically based human eye model, which incorporates a gradient index crystalline lens. Graphesthesia: a test of graphemic movement representations or tactile imagery?. The ATPase is required to provide energy for translocation and compaction of the negative charges on the genomic DNA.

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Several cases of psoriasis associated with bullous disorders have been reported, and it is clearly recognized that bullous pemphigoid (BP) is the most common bullous disorder observed in association with psoriasis, especially after ultraviolet (UV)B and psoralen UVA therapy. Cancer epidemiology in populations of the United States--with emphasis on Hawaii and California--and Japan. The DNA sequence method detects more CFTR mutations than common mutation panels. We have studied the changes in the serum level of the following cytokines during the course of treatment of nosocomial pneumonia (NP): pro-inflammatory--IL-1alpha and IL-6, chemoattractive--IL-8, anti-inflammatory--IL-4 and IL-10, and differentiating-activating--IFN-gamma and TNF-alpha. We have previously demonstrated in vivo the significant involvement of semicarbazide-sensitive amine oxidase (SSAO) in this reaction. This hypothesis is supported by the oil/water partition coefficients.

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The upregulation of lysosomal enzymes, the release of cytochrome c (cyto-c), and the nuclear translocation of the apoptosis inducing factor (AIF) were examined by immunoblotting and immunofluorescence. An international case-control study of interleukin-4Ralpha, interleukin-13, and cyclooxygenase-2 polymorphisms and glioblastoma risk. We have previously examined the ability of air pollution particles (PM(10)) to promote release of the proinflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) from human peripheral blood mononuclear cells and demonstrated a role for calcium as a signaling molecule in this process. The resected specimen measured 28.6 x 18.3 x 8.2 cm and weighed 2,200 g. To compare the effectiveness of oral moxifloxacin with standard antibiotic therapy in acute exacerbation of chronic bronchitis (AECB).

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Response to a behavioural treatment, biofeedback, in constipated patients is associated with improved gut transit and autonomic innervation. Cd-induced tissue damage became marked in the 2y-Cd-exposed mice compared to the 1.5y-Cd-exposed mice, in which nephrotoxicity was more prominent than hepatotoxicity. Our results showed that client-centered therapy is less effective than exercise in reducing disability at short term. Each year more than 400,000 Americans die from diseases directly related to smoking, and lung cancer is now the leading cause of death from neoplasia in U.S. The abstracts of searched articles about surgical management of CP were reviewed. Maximum intensity projection (MIP) and volume rendering (VR) images were excellent in demonstrating stenosis of the renal arteries. Attenuation of Th1 effector cell responses and susceptibility to experimental allergic encephalomyelitis in histamine H2 receptor knockout mice is due to dysregulation of cytokine production by antigen-presenting cells. Effect of ginsenoside Re on cardiomyocyte apoptosis and expression of Bcl-2/Bax gene after ischemia and reperfusion in rats. Two percent lidocaine spinal anaesthesia compared with sevoflurane anaesthesia in ambulatory knee surgery - cost-effectiveness, home readiness and recovery profiles.

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First, abdominal lipectomy and lipoaspiration of the internal and external face of the thigh are performed. We report simulation results that confirm these characteristics of the proposed system. The aim of this study is to examine the relevant factors amiloride dosing affecting the duration of mechanical ventilation after orthotopic liver transplantation. These data identify a novel role for the PLD1 isoform in the induction of gene expression and provide new insight into the differential role of PLD1 and PLD2 in cells. Further, some of the mid-secretory phase proteins were conserved across species. The occurrence of motor neuron disease after electrical injury in six patients is reported and compared with patients from the literature.

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This clone, which is fully susceptible to antibiotics but not included in the heptavalent conjugate vaccine, should be closely monitored. The interaction between osteons and microcracks is evaluated by linear elastic fracture mechanics theory, followed by a determination of the stress intensity factor at the vicinity of the microcrack tips. In nine cases, physical signs of anaphylaxis recurred after initial attempts at stopping adrenaline but resolved after recommencing the infusion. If there is restriction of variation at certain types of loci, a limit is placed on the number of loci which can play a role in multigenic inheritance. Fine structural alterations of the submandibular glands were observed with an electron microscope. Appropriate investigation of novel causes for RPL may decrease the percentage of patients carrying the diagnosis of unexplained RPL. Results from simulations and in vivo pulsed-gradient-spin-echo (PGSE) experiments show that the apparent diffusion coefficient (ADC) is a function of diffusion time and gradient strength, and suggests diffusion is locally anisotropic. Here, we investigate if KCC is involved in the regulation of epithelial-mesenchymal transition (EMT), a critical cellular event of malignancy. Pruritus was refractory to all treatments, including topical lidocaine, gabapentin, transcutaneous electrical nerve stimulation, intravenous Bier block, stellate ganglion block, and acupuncture. Under these conditions, ethanol did not stimulate the proliferation of nonconfluent cells, but significantly increased maximal is pepcid ac safe while breastfeeding cell density.

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However, it has not been clarified how DPCs are repaired in cells. Results show that after internalization, the bacteria induced morphological, functional and genetic changes in the cells characteristic of apoptosis, which was dose-and time-dependent on listeriolysin O. Fast Second Order Learning Algorithm for Feedforward Multilayer Neural Networks and its Applications. In view of these findings, we investigated the effects of our synthetic bombesin and gastrin-releasing peptide receptor antagonist D-Tpi6,Leu13 psi (CH2NH)-Leu14 bombesin(6-14) (RC-3095) on the growth of hormone-dependent and hormone-independent MXT mouse mammary cancers in vivo. Using UBM, we measured anterior chamber depth (ACD) and iris convexity (IC): the maximum distance from the posterior surface of the iris to the iris plane passing through the pupillary margin of the iris and iris root. Characteristics of synthesis of proteins in coelomic fluid in Bombyx mori L.

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6, 12 and 24 h after application of serotonin on the 15th or 18th day of pregnancy, the placenta is examined. A computational modeling capability is being developed for the study of geochemical reactions at the outer bacterial envelope of Gram-negative bacteria. DNA was extracted from the tumour tissue of 26 patients (18 smokers, 8 non-smokers) undergoing surgery for gastric cancer, and analyzed for the presence of DNA adducts by the 32P-post-labelling method. In our previous study, Rheum tanguticum polysaccharide (RTP), extracted from traditional Chinese medicine rhubarb, targeted mannose receptor why does zovirax cost so much , showed immunoregulatory effect on the balance of Th1 and Th2 polarization in colitis rats. We obtained 45 degrees flexed weightbearing posteroanterior radiographs on 517 patients who had knee problems other than an anterior cruciate ligament injury or arthrosis. The phase boundary is calculated beyond RPA by including the leading correction due to quantum fluctuations. Assessment and management of broad complex tachycardia is challenging but requires a structured approach to the underlying differential diagnosis. Purification and characterization of a beta-galactosidase from peach (Prunus persica). The identification of low selenium levels in patients who experience CAR or CMV (two important risk factors for clinically apparent CGN) suggests that the relationship between selenium and CGN warrants further investigation. Implementation of PILs takes time, and there are great advantages to integrating them into the existing Family Practice Information Systems.

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The increase in coronary blood flow, caused by intracoronary arterial administration of KRN2391 was not affected by intravenous infusion of KRN2391 (0.3 or 1 micrograms/kg/min), isosorbide dinitrate (30 or 100 micrograms/kg/min) or nitroglycerin (1 or 3 micrograms/kg/min). Finally, we developed an assay based on a reporter gene plus pseudotyped virus that could sensitively detect fusion activity. The mutation was found to be neither associated with the lymphomas per se, nor with any signs, symptoms or laboratory findings of MPD. Determination of tar, nicotine, and carbon monoxide yields in the mainstream smoke of selected international cigarettes. Ultrastructural changes induced by vinblastine in cutaneous lesions of histiocytosis X. Transplantation of endothelial-expanded neural stem cells that were treated with sonic hedgehog(Shh) and retinoic acid (RA) during the expansion phase, into an adult mouse SCI model resulted in significant recovery of sensory and motor function. Stenting has been used as an alternative treatment for patients with internal carotid artery (ICA) stenosis. It requires physicians to make an accurate diagnosis and report of occupation-related diseases.

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In the control group, the hearts were perfused with crystalloid cardioplegic solution (CPS) every 20 minutes during arrest. Patients with chronic renal failure are characterized by increased plasma levels of C-reactive protein (CRP) and advanced glycation end products (AGE). We conclude that endothelin-1 abolishes the negative inotropic effect of CNP. Using ultrathin cobalt films grown on Cu(001), we observe unoccupied quantum well states which give rise to a sizable intensity change in photoemission under magnetization reversal. how long does klonopin show on a drug test Infections with antibiotic-resistant bacteria (ARB) in hospitalized patients are becoming increasingly frequent despite extensive infection-control efforts. A phylogenetic study of South African Newcastle disease virus strains isolated between 1990 and 2002 suggests epidemiological origins in the Far East. Ventilation in the prone position is a valid choice in the treatment of trauma patients with acute respiratory distress syndrome (ARDS).

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The radius of the effective interaction volume is estimated to be r(m) approximately 12.5 nm, and the interaction cross section for nonequilibrium phonon-TLS scattering is estimated as approximately 10(-22) cm2. The effects of amplitude and phase modulation on the spectrum are described and compared with theory. Of note is that each of the potential donors was discovered to have the same disease as the transplant recipient. Our findings suggest that inhibition of the interaction between IL-17 from T cells and SDF-1 in FLS may provide a new therapeutic approach in RA. Functional analysis of murine uterine natural killer cells genetically devoid of oestrogen receptors. Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Purification, crystallization and initial crystallographic characterization of brazil-nut allergen Ber e 2. Negative selection of T cells by aygestin pill Helicobacter pylori as a model for bacterial strain selection by immune evasion. We report what we believe to be the first case of ascites caused by Agrobacterium tumefaciens in a cirrhotic patient. Selective impairment of facial recognition due to a haematoma restricted to the right fusiform and lateral occipital region.

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By regulating downstream substrates that include protein kinases and transcription factors, p38 participates in transmission, amplification, and diversification of the extracellular signal, initiating several different cellular responses. The clinical target volume (CTV) consisted of the prostate and seminal vesicles in all cases. The female never mates again after laying eggs and the LNSC also never become active. Although women live on average approximately 7 years longer than men, their later years are often filled with medical problems. FK 506 caused a transient increase of intracellular calcium levels in cultured cells. Modifications in neuropeptide Y and proopiomelanocortin were not consistent with changes in food intake. Electron surfing acceleration which requires a stable saturated wave may thus be more important for electron acceleration at shocks than previously thought. Helospectin I and II evoke vasodilation in the intact peripheral microcirculation. High uptake of TPMT enzyme-level testing by dermatologists, compared with gastroenterologists and rheumatologists, may reflect national guidelines advocating its use prior to AZA. Electron-capture processes by negatively charged dust grains from hydrogenic ions in dusty plasmas are investigated in accordance with the classical Bohr-Lindhard model.

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