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Amitrol (Amitriptyline)

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Amitrol is sometimes used off-label, meaning not FDA approved, for certain conditions. Some providers will use this medication to treat nerve pain. This can be helpful for people who have diabetes or fibromyalgia and haven't felt relief with other medications.

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Also known as: Amitriptyline


Amitrol (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

Amitrol is a prescription medicine used to treat symptoms of depression.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amitrol dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amitrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Amitrol if you are allergic to Amitrol components. Do not take Amitrol if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful with Amitrol if you suffer from or have a history of a history of heart attack, stroke, bipolar disorder (manic-depression), schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, problems with urination, heart disease, seizures. Be careful with Amitrol if you are taking guanethidine (Ismelin), disulfiram (Antabuse), heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), quinidine (Cardioquin, Quinidex, Quinaglute), cimetidine (Tagamet). Avoid alcohol. Be careful! Taking Amitrol you can become suicidal. Be careful when you are driving or operating machinery. Be careful with Amitrol if you are going to have a surgery. It can be dangerous to stop Amitrol taking suddenly.

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Evaluation of the KOH test and the antibiotic disk test in routine clinical anaerobic bacteriology. Given its widespread use, it is important to identify the outcomes associated with ICD use in patients with HCM. Recanalization was observed 60 minute after the beginning of IAT, with NIHSS score being decreased to 14. Assessing the impact of ambient ozone on growth and yield of a rice (Oryza sativa L.) and a wheat (Triticum aestivum L.) cultivar grown in the Yangtze Delta, China, using three rates of application of ethylenediurea (EDU). Kidney injury molecule-1 expression in transplant biopsies is a sensitive measure of cell injury. Our results suggest that Pg gingipains are involved in the induction of SMC transformation and proliferation, whereas this was inhibited by AP.

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Admixture between genetically different populations may produce gametic association between gene loci as a function of the genetic difference between parental populations and the admixture rate. Production and cleaning of freeze-etch replicas which show complementary surfaces of fractured fungus spores and hyphae. A flow phantom was constructed and water was the experimental fluid. At 3 1/2 years after surgery, the patient continues to walk without a limp, and the mechanical function of ativan dosage the forefoot has been largely restored, although considerable loss of function of the big toe is apparent. The main indications are pulmonary embolism or extensive deep vein thrombosis when anticoagulants are contraindicated, and recurrent pulmonary embolism despite adequate anticoagulation. Clinical management of EGFRI dermatologic toxicities: the European perspective.

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Murine CD8 lymphocyte expansion in vitro by artificial antigen-presenting cells expressing CD137L (4-1BBL) is superior to CD28, and CD137L expressed on neuroblastoma expands CD8 tumour-reactive effector cells in vivo. Relative contributions of water quality to endemic waterborne disease for particular categories of magnesium concentration and for age groups of patients were ascertained, i.e. Open Bankart repair plus inferior capsular shift versus arthroscopic Bankart repair without augmentations for traumatic anterior shoulder instability: A prospective study. This method is simple, fast and sensitive, suitable for determining the dencichine in P. At this point in the disease process, few opportunities exist to prevent adverse outcomes. An optics simulator is then used to compute the incident photon flux on the imaging plane for a given photon flux and system geometry. SCOOP is freely is imovane a good sleeping pill available under a GNU GPL license from The role of SIRT6 in the differentiation of vascular smooth muscle cells in response to cyclic strain. We developed Socs3 hepatocyte-specific knockout (Socs3 h-KO) mice to directly study the role of SOCS3 during liver regeneration after a two-thirds partial hepatectomy (PH). NOS II inhibition restores attenuation of endothelium-dependent hyperpolarization in rat mesenteric artery exposed to lipopolysaccharide.

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