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Amitrol (Amitriptyline)
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Amitrol

Amitrol is sometimes used off-label, meaning not FDA approved, for certain conditions. Some providers will use this medication to treat nerve pain. This can be helpful for people who have diabetes or fibromyalgia and haven't felt relief with other medications.

Other names for this medication:
Abamax, Amicon, Amicure, Amidez, Amiline, Amitar, Amitop, Amitrim, Amitrix, Amitrol, Amize, Amizep, Amline, Amsha, Anitryp, Arpidox, Axtrip, Chlotrip, Eliwel, Goldep, Libral, Limbitrol, Maxitrip, Mitrip, Mitryp, Psycomer, Raitrip, Ristryl, Sereval, Tablin, Teedep, Tridep, Triplent, Trixide, Typlin, Vanatrip, Zodep

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Also known as: Amitriptyline

Description

Amitrol (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

Amitrol is a prescription medicine used to treat symptoms of depression.

Dosage

Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amitrol dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amitrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Amitrol if you are allergic to Amitrol components. Do not take Amitrol if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful with Amitrol if you suffer from or have a history of a history of heart attack, stroke, bipolar disorder (manic-depression), schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, problems with urination, heart disease, seizures. Be careful with Amitrol if you are taking guanethidine (Ismelin), disulfiram (Antabuse), heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), quinidine (Cardioquin, Quinidex, Quinaglute), cimetidine (Tagamet). Avoid alcohol. Be careful! Taking Amitrol you can become suicidal. Be careful when you are driving or operating machinery. Be careful with Amitrol if you are going to have a surgery. It can be dangerous to stop Amitrol taking suddenly.

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The intestinal side effects of anti-tumoural therapy can be so severe as to preclude its clinical efficacy, although the use of selected nutrients and growth factors may ameliorate the noxious effects. Simple frequency and descriptive statistics were used to analyze data using SPSS statistical software. Osteoarthritis is the most common form of arthritis and a major socioeconomic burden. Based on comparison of gid1 multiple mutants to sly1 gid1 mutants, GID1a is the primary GA receptor stimulating stem elongation in proteolytic and non-proteolytic signaling, and stimulating fertility in proteolytic GA signaling. An 11-year-old girl presented with a swollen medial aspect of the left forefoot following a blunt injury. An equatorial contractile mechanism drives cell elongation but not cell division. We demonstrated that HDAC class II and IV members are differentially expressed during osteoclast differentiation. All mutants show one or two amino acid substitutions which are discussed to destabilise the pH 7 conformation of hemagglutinin. We therefore undertook this study to examine the relationship between albuminuria and all-cause, cardiovascular disease (CVD) and non-CVD mortality in the general population. In the present report we have examined somal size development in medial gastrocnemius (MG) motor nuclei in 18 cats aged 2 dPN to adulthood using retrogradely transported horseradish peroxidase to label the motoneurons.

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Biomarkers assessment in juvenile Cyprinus carpio exposed to waterborne cadmium. For instance, secondary growth of Arabidopsis hypocotyls creates a radial pattern of highly specialized tissues that comprises several thousand cells starting from a few dozen. The series of experiments did reveal a slight advantage for testing memory with moving compared with static faces, consistent with recent findings using familiar faces. Additionally, a few more recent avenues of theoretical investigation, including the study of defect states, are discussed. Tissue or nerve injury can dramatically alter the transmission of sensory stimuli by spinal cord neurons, so that a light touch produces pain. However, it is unclear if c-myb-null embryos harbor definitive erythroid or any megakaryocyte progenitors. Inactivation of the perR gene resulted in constitutive, iron-independent high-level expression of the katA and ahpC transcripts and corresponding proteins. Polymethylmethacrylate IOLs were irradiated by a Q-switched Nd:YAG laser beam focused so that plasmas were formed well clear of the IOL.

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Evaluation of the KOH test and the antibiotic disk test in routine clinical anaerobic bacteriology. Given its widespread use, it is important to identify the outcomes associated with ICD use in patients with HCM. Recanalization was observed 60 minute after the beginning of IAT, with NIHSS score being decreased to 14. Assessing the impact of ambient ozone on growth and yield of a rice (Oryza sativa L.) and a wheat (Triticum aestivum L.) cultivar grown in the Yangtze Delta, China, using three rates of application of ethylenediurea (EDU). Kidney injury molecule-1 expression in transplant biopsies is a sensitive measure of cell injury. Our results suggest that Pg gingipains are involved in the induction of SMC transformation and proliferation, whereas this was inhibited by AP.

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We have investigated the expression of a member of this family, EphB4, and its cognate ligand, ephrin-B2, during normal and malignant mouse mammary morphogenesis. Structural identification of compounds for use in the detection of juice-to-juice debasing between apple and pear juices. To this end, cell perifusion of both hemihypothalamic tissue and enzymatically dispersed hypothalamic tissue isolated from adult male rats was performed. In the case of stage I of mucinous ovarian cancer with the low tumor grade, the necessity of a complete surgical staging should be reconsidered. Paraganglioma is a neoplasm of neuroectodermal origin that occurs rarely in the bowel. Internal quality control provides the means for evaluation of analytic test results at the time of testing in order to decide whether they are reliable enough to be released to the requesting clinicians. Choroideremia is a severely debilitating disease showing a rapid decline of visual acuity generally after the age of 35, but a more gradual decline for other abnormalities. To bring further understanding to the relationship between hormonal therapy (HT) and breast arterial calcification (BAC). A cross-sectional study of 164 schoolchildren aged 12-13 years was conducted in two schools. Subsequent optimization led to 15, a potent, selective, and orally bioavailable inhibitor of uPA.

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Murine CD8 lymphocyte expansion in vitro by artificial antigen-presenting cells expressing CD137L (4-1BBL) is superior to CD28, and CD137L expressed on neuroblastoma expands CD8 tumour-reactive effector cells in vivo. Relative contributions of water quality to endemic waterborne disease for particular categories of magnesium concentration and for age groups of patients were ascertained, i.e. Open Bankart repair plus inferior capsular shift versus arthroscopic Bankart repair without augmentations for traumatic anterior shoulder instability: A prospective study. This method is simple, fast and sensitive, suitable for determining the dencichine in P. At this point in the disease process, few opportunities exist to prevent adverse outcomes. An optics simulator is then used to compute the incident photon flux on the imaging plane for a given photon flux and system geometry. SCOOP is freely is imovane a good sleeping pill available under a GNU GPL license from http://www.sanger.ac.uk/Users/agb/SCOOP/. The role of SIRT6 in the differentiation of vascular smooth muscle cells in response to cyclic strain. We developed Socs3 hepatocyte-specific knockout (Socs3 h-KO) mice to directly study the role of SOCS3 during liver regeneration after a two-thirds partial hepatectomy (PH). NOS II inhibition restores attenuation of endothelium-dependent hyperpolarization in rat mesenteric artery exposed to lipopolysaccharide.

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