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Amiline (Amitriptyline)
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Amiline

Amiline is a medicine used for treating pain. You can take it: to treat nerve pain (neuralgia) and back pain. to help prevent migraine attacks. The FDA withdrew the drug in 2000 following reports that it increased the risk of heart problems. Doctors may still prescribe the drug, but only in rare cases when it is necessary.

Other names for this medication:
Amiclozor, Amicon, Amidez, Amiline, Amimax, Amitin, Amitone, Amitrip, Amitrix, Amitryptyline, Amixide, Amizep, Amtipax, Amypres, Bluneel, Cotrip, Estiline, Gentrip, Goldep, Kamitrin, Latiln, Limbitrol, Lodep, Mitrip, Nextrip, Normaline, Raitrip, Relidep, Sarotena, Sereval, Tablin, Tadamit, Tridep, Triplent, Trixide, Tryptomec, Vanatrip, Zodep

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Also known as: Amitriptyline

Description

Amiline (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

Amiline is a prescription medicine used to treat symptoms of depression.

Dosage

Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amiline dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amiline are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Amiline if you are allergic to Amiline components. Do not take Amiline if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful with Amiline if you suffer from or have a history of a history of heart attack, stroke, bipolar disorder (manic-depression), schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, problems with urination, heart disease, seizures. Be careful with Amiline if you are taking guanethidine (Ismelin), disulfiram (Antabuse), heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), quinidine (Cardioquin, Quinidex, Quinaglute), cimetidine (Tagamet). Avoid alcohol. Be careful! Taking Amiline you can become suicidal. Be careful when you are driving or operating machinery. Be careful with Amiline if you are going to have a surgery. It can be dangerous to stop Amiline taking suddenly.

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Homologous chromosomes must pair and establish stable connections during prophase I of meiosis to segregate reliably from each other at anaphase I. Low-dose fractionated radiotherapy to the upper abdomen is well tolerated at 60 cGy per fraction when combined with gemcitabine. Reconstruction of the anophthalmic orbit by orbital osteotomy and free flap transfer. To investigate the EGF effect on hOAT1, CHO-hOAT1 cells were additionally co-transfected with the human EGF receptor HER1. Specific reading difficulties in Chinese, English, or both: longitudinal markers of phonological awareness, morphological awareness, and RAN in Hong Kong Chinese children. The system is capable of generating curves relating RV volumes and pressures, which are critical in evaluation of heart failure (HF) patients.

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From the results obtained in the current study, it could be concluded that exposure to cadmium and arsenic through the food chain leads to accumulation of these metals in the tissues of experimental rats leading to the inhibition of oxidative enzymes, thus affecting several normal metabolic processes. Fibroblasts supplemented with galactose showed restoration of protein glycosylation and no evidence of glycogen accumulation. Wnt/LRP5, a new regulation osteoblastic pathway involved in reaching peak bone masses. Coronary stenting for acute myocardial infarction in a patient with an anomalous origin of the left main coronary artery. This paper describes the firsts results achieved in the project on the technological platform and the fitness condition assessment. We report herein the clinical and pathological presentation of three cases of SAFM located solely under the matrix. Two previous surveys performed in the same area were used to plot a trend over a 20 year period. In this algorithm, hundreds of frames are initially distributed randomly over the electron micrograph in which multi-particle images are dispersed. 2-Drug regimens in HIV treatment: pharmacological considerations.

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From 114 matched pairs, we found no significant differences in mortality rates or numbers of surgical procedures performed between the groups. A plasmonic photocatalyst consisting of silver nanoparticles embedded in titanium dioxide. The observed parallelism in evolution indicates the existence of a constraint on the genetic elements determining ellisellid colonial morphology. A preliminary in vitro evaluation of the bioactive potential of cryogel scaffolds incorporated with Manuka honey for the treatment of chronic bone infections. After a 3 month course of oral corticosteroids the mediastinal lymphadenopathy, pleural effusion and hepatic nodules resolved. Bacterial infections of the lung in normal and immunodeficient patients. It was very recently shown that this system is also capable of de novo production of biologically active forms of heterologous nonribosomal peptides, echinomycin and triostin A, through the introduction of genes encoding modules responsible for their assembly into this model bacterial host. DUD was more strongly associated with the prognosis of depression at follow-up than depression and anxiety severities at baseline.

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Centuries of artificial selection in domestic rock pigeons (Columba livia) have cultivated tremendous variation in plumage pigmentation through the combined effects of dozens of loci. The role of the interstitial cells in the internal anal sphincter was assessed. Gait disorder is a common complaint in general practice, in particular in the elderly, and more than one cause frequently interact to produce various abnormalities of gait, including neurological, orthopedic, rhumatologic or ophthalmologic conditions, among others. There were 15 complications among 45 reconstructive procedures, for an overall 33 percent complication rate. cholerae biofilm development and its environmental adaption in host niche and aquatic habitat. Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes. Direct linkage between the plasma membrane and the actin cytoskeleton is controlled by the protein ezrin, a member of the ezrin-radixin-moesin protein family.

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Neurosporaside, a tetraglycosylated sphingolipid from Neurospora crassa. Quantum beats in hydrogen and antihydrogen atoms in an external electric field. We studied response rate, time to progression, and toxicity profile. Virtually every article reviewed supports the view that cost sharing decreases the use of prescription drugs in these populations. Lesions to the core areas impaired auditory localization abilities. The aberrant regulation of the protein tyrosine kinase (PTK) activity of P210(BCR-ABL), which is the protein product of Bcr-Abl fusion gene leads to the pathogenesis of chronic myeloid leukemia (CML).

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Prevalence and pathology of helminth parasites in domestic ducks of Bangladesh. The developing thymocytes were examined at different time intervals during the first week of culture. It also contrasts the effects of UVB and UVA on cellular changes involved in immunosuppression. Ambient pollution did not appear to influence the growth of Sitka spruce at least over the experimental period used. As the questions about drug safety appeared after the animal study had been published about possible myocyte injury, detailed Doppler evaluation of IVC blood flow was performed. The analyses of the spontaneously reported adverse events support the good safety profile of the MF59-adjuvanted H1N1v pandemic influenza vaccine. We aimed to investigate subjective and brain responses during anticipatory fear and subsequent induction of vestibular pain in women with GPPPD.

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The consequent reduction in the cost and time necessary to reach a final product has enabled the multiplication of transgenic prototypes around the world. Successful use of resuscitative endovascular balloon occlusion of the aorta in the treatment of ruptured 8.5-cm splenic artery aneurysm. A distinct advantage of this approach is the ability to introduce systematic perturbations in model backbone atoms in addition to side chain adjustments. The Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades are often activated by genetic alterations in upstream signaling molecules such as receptor tyrosine kinases (RTK). The sequence of the chromosomal fragment containing the leucine cluster and flanking genes has different positions in the chromosome in B. Neuroprotective effects of the cannabinoid agonist HU210 on retinal degeneration.

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Like other industrial countries Germany experiences a significant increase of cancer prevalence. Time relationships of sporopollenin synthesis associated with tapetum and microspores in Lilium. Vector competence of Ixodes scapularis and Ixodes ricinus (Acari: Ixodidae) for three genospecies of Borrelia burgdorferi. Activated carbon (AC) has been used extensively in personal protective equipment (PPE) to adsorb toxic substances for the purpose of protecting the user from exposure. Biological fate of tritiated p-biphenylmethyl-(dl-tropyl-alpha-tropinium)-bromide in the rat. However, protected rats harbor potentially encephalitogenic T cells, which are maintained in an inactive state. Instillation of large quantities of LPS into the lumen of the intestine produced scattered microvascular lesions, although none of these animals developed diarrhea. Outlined in the paper are outlooks for determining a group affiliation of sperm in traces, left in material evidence, within forensic biological expertise. We conclude that understanding plasticity is fundamental to modern neurosurgical education and practice.

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Testosterone therapy in young and old rhesus males that display low levels of sexual activity. In the present review we discuss the role of established molecular markers, as well as potential applications of emerging new technologies. The use of the Narcotics Register for follow-up of a cohort of adolescent addicts. Monte Carlo evaluation of specific dose constants in water for 125I seeds. Defibrillation current density imaging: comparison of in-vivo and post-mortem measurements in a pig. To compare the prevalence of disruptive behavior problems between preschool-aged children with hearing loss and normal hearing.

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The presented core set is a secure, fast, and accurate instrument for assessing the physical health and engagement of older adults. Large-scale deformation of continents remains poorly understood more than 40 years after the plate tectonic revolution. Despite the promising safety profile demonstrated in clinical trials, the efficacy of using adenoviruses for gene therapy is poor. It involves the treatment of mucoid cultures with testicular hyaluronidase. The role of childhood abuse in Axis I and Axis II psychiatric disorders and medical disorders of unknown origin among irritable bowel syndrome patients. 1 to 4 iris retractors were used during surgeries, according to the extension of zonular loss and nuclear hardness. Patients with psychogenic nonepileptic seizures (PNES) rate their health-related quality of life (HRQOL) more poorly than those with epileptic seizures (ES). Survival improvement was greater for platinum-sensitive patients if they were treated with the predicted most beneficial drugs. Comparison of this second fit with the first using an F test permits a statistical decision to be made on the type of inhibition.

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Cardiac actinomycosis in a patient presenting with acute cardiac tamponade and a mass mimicking pericardial tumour. Nearly 80 per cent of patients reported long-term relief of symptoms. The recipients were treated with cyclosporin A (5 mg/kg/day) by daily intramuscular injection for 30 days, beginning on the day of transplantation. The very high amounts of REM sleep seen in the platypus also fit with the increased REM sleep duration seen in altricial mammals. This approach led to a more realistic appraisal of both risks and benefits of the fungicides, lowering risks and raising benefits. This review discusses the role of the contact system in these processes, and highlights the potential of FXII and FXI as safer targets for antithrombotic therapy. Efficacy and safety of clofarabine in relapsed and/or refractory non-Hodgkin lymphoma, including rituximab-refractory patients.

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Diagnosis of gestational diabetes mellitus using a modified 100 g oral glucose tolerance test. Among 11 PDZ domains that have not been reported their internal PBM binding ability, six were confirmed to bind internal PBMs. Herein, we report a case of hepatic hemangioma demonstrating a previously unreported atypical enhancement pattern. The production of singlet molecular oxygen (1O2) by the photosensitizing dye maximum dosage of amaryl merocyanine 540 (MC540) bound to phosphatidylcholine liposomes has been demonstrated by direct detection of 1O2 luminescence at 1268 nm. The English-language literature indexed on MEDLINE/PubMed was searched for original observational studies (controlled and uncontrolled, prospective and retrospective), case reports, and case series that evaluated or described pharmacokinetic changes or TDM during pregnancy or the postpartum period.

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Three nephrectomy specimens with transitional cell carcinoma (TCC) of the renal pelvis were thoroughly examined by both light and scanning electron microscopy. In the present study, we compared the secretion of MMP-2, MMP-3 and MMP-9 among 29 benign and premalignant cervical lesions (cervicitis and cervical intraepithelial neoplasias) and 46 tumoral explants of Ce Ca. The consequent consideration of the whole labelled steroidal spectrum in each experiment leads to the conclusion that androstenedione and the derived aromatase inhibitors activate the 17 beta-hydroxysteroid-dehydrogenase in a product activating manner. How long-lasting T-B interactions and B cell clonal expansion are regulated by antigen presentation remains unclear. Schizophrenia (SZ) is a neurodevelopmental disorder with a broad symptomatology, including cognitive symptoms that are thought to arise from the prefrontal cortex (PFC). Effects of endothelin-1 on capsaicin-induced nociception in mice. MAPT is a neuronal protein that plays an important role in axonal stabilization, neuronal development, and neuronal polarity.

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Auditory hallucinations are one the most enigmatic and hampering symptoms associated with schizophrenia. At the end of CBT, subjects whose scores on the Eating Disorders Examination indicated that they were abstinent from binge eating and purging, and therefore considered to be treated successfully, were assigned randomly to follow-up only or to a crisis intervention model. The origin of most non-communicable diseases (NCDs) is in early life. Occupational immunization recommendations may vary between countries, but always include vaccine-preventable diseases that might lead to nosocomial outbeaks and/or fatal outcomes for healthcare workers or patients. Prognosis was known to be better in patients with neurofibromatosis 1 (NF1) than those with non-NF1. The protonophoric (uncoupling) action of various long-chain fatty acids and their derivatives in mitochondria was investigated as related to their ability for rapid transbilayer movement in the inner mitochondrial membrane (flip-flop) and interaction with the ADP/ATP carrier (AAC).

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Reactivating the p53 pathway in tumors is an important strategy for anticancer therapy. The plate image was scanned, analysed and interpreted automatically. Intraoperative neurophysiological monitoring in patients undergoing tethered cord surgery after fetal myelomeningocele repair. Pulmonary-renal syndrome developing in SSc patients can be categorized clinicopathologically into three entities: PRS with thrombotic microangiopathy, PRS with small vessel vasculitides accompanied with SSc, and d-penicillamine-induced Goodpasture-like syndrome. RNA interference ( temovate brand name RNAi)-mediated repression of AP2a resulted in alterations in fruit shape, orange ripe fruits, and altered carotenoid accumulation. Computational modeling studies were used to explain some trends in the observed selectivity profiles. In vivo fabrication of a temporary prosthesis for maxillofacial avulsion wounds: a clinical trial in Vietnam. Cross infection between cystic fibrosis patients colonised with Burkholderia cepacia.

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The expression of NF-kappa B was evaluated by immunohistochemistry. Spiral correlations in frustrated one-dimensional spin-1/2 Heisenberg J1-J2-J3 ferromagnets. The keratinocyte growth factor (KGF) palifermin has been approved as a new, targeted therapy for the prevention of severe oral mucositis. Rat prolactin stimulated PKC maximally at 10(-12) M, whereas ovine prolactin was maximally stimulatory at 10(-10) M. jasminoides by the standard D65 light source and image acquisition system, quantifing the gardenia plumpness information by the digital display vernier caliper, determinating 6 kinds of effective components of G. The CPT codes describe the type of services provided to a patient. Liver transplant outcomes using grafts donated after cardiac death (DCD) remain poor. Synthesis and antiviral evaluation of 6-(trifluoromethylbenzyl) and 6-(fluorobenzyl) analogues of HIV drugs emivirine and GCA-186. In Experiment 2, FR rats given access to a running wheel for a brief period outside of the home cage rapidly acquired wheel running while AL rats did not. Analysis of a survey of blind patients of empoyable age in a large town.

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A comparison between midline, oblique and transrectal incisions. Recently, several new techniques and methods based on gene technology have been developed, such as the polymerase chain reaction, fluorescence in situ hybridization, and the use of microsatellite polymorphism. The VPT group demonstrated less hippocampal infolding than the FT group at 7 years. Chemical and microbiological contaminants as well as the electrolyte and buffer composition of the dialysis fluid play major roles in the induction or modulation of morbidity associated with regular dialysis therapy. Degradation proceeds by selective hydrolysis of that phosphodiester group attached to an alcoholic hydroxyl group of the N-acetylglucosamine and gives a repeating unit in high yield. The mean intraobserver kappa coefficient for fracture classification using plain radiographs was 0.60, which decreased to 0.57 with addition of CT scans. To determine the incremental cost-utility of LNF versus PPI for treating patients with chronic and controlled GERD over 3 years from the societal perspective. Effects of herbicides on two submersed aquatic macrophytes, Potamogeton pectinatus L. Effects of tadalafil on nighttime voiding (nocturia) in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: a post hoc analysis of pooled data from four randomized, placebo-controlled clinical studies. We studied 562 consecutive subjects including 357 healthy, 155 pre-diabetic, and 50 diabetic patients selected from participants who underwent annual health surveys in Taiwan.

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To address the molecular mechanism underlying the functional defects of peripheral T cells in systemic lupus erythematosus (SLE), we focused on early signaling events. Coincidence of factor V Leiden mutation and a mutation in the prothrombin gene at position 20210 in a patient with puerperal cerebral venous thrombosis. Spectroscopic analysis reveals that in addition to the two main absorption peaks, centered at around 583 and 635 nm, the absorption spectrum in the spectral range from can you take prilosec 20 mg twice a day 350 to 800 nm contains six more absorption bands. Neighbourhood effects on health: does it matter where you draw the boundaries?. Tension was significantly increased on the dorsal nerve roots being tethered by the lumbar intrathecal ligaments in comparison to non-tethered nerve roots during lengthening of the vertebral column. Creatine is found in high protein foods, such as fish or meat, and is also produced endogenously from the biosynthesis of arginine, glycine, and methionine. At the same time, expressions of the lactate dehydrogenase (LDH) and monocarboxylate transporter 1 (MCT1) genes were significantly decreased by SNP in SHRSP compared with WKY. It was reported on 30 heparin-free hemodialyses in 7 chronic patients by means of the capillary dialyzer MLW Typ II.

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