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Alprotame (Alprazolam)

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Alprotame is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alprotame is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alprotame may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Alamflu, Alcicalm, Alpracon, Alpranex, Alprazolam, Alprogard, Alpronit, Alprosym, Alprozam, Alzolam, Alzomax, Ambulax, Andep, Anilam, Azolam, Balmusa, Cardilax, Copax, Elflu, Emlol, Endep, Enxolam, Flumusa, Hipose, Isorest, Kaprolam, Mebrin, Notence, Orten, Restam, Synozolam, Tenschem, Visram, Welnorm, Xylonite, Zedel, Zeecam, Zenax, Zocam, Zolark, Zoltweet, Zopax, Zotam

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Daklinza, Aristocort, Colospa, Celebrex, Silagra, Clarinex, Alendix, Amiwel, Lemorcan, Azithro, Voglimac, Ristal, Alfoo, Biscolet,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprotame XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alprotame are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

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The organochlorine contamination history of the Mersey estuary, UK, revealed by analysis of sediment cores from salt marshes. Four patients with an unusual pigmented purpuric eruption are presented. This cozaar losartan dose paper addresses the problem and offers a new technique of direct puncture of prosthetic grafts through which thrombolysis and angioplasty can be performed. In indomethacin-treated bones, however, caffeine potentiated the stimulatory effect on 45Ca release induced by choleratoxin and forskolin. There is worldwide recognition that an unobtrusive and noninvasive measurement technique will better enable the patient with diabetes to obtain information for appropriate disease management. Effect of prolonged administration of insecticide (Cyhalothrin/Karate) on the blood and liver of rabbits. Immune activation by life-shortening Wolbachia and reduced filarial competence in mosquitoes.

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Activity of serotonin in the blood of animals in acute radiation sickness. Glucose fermentation with Actinobacillus succinogenes was carried out at different initial concentrations of succinic acid (SA(0)) to determine its effect on growth and on the production of succinic acid itself. Our work suggests that mutual validation of protein expression profiles using alternative microarray platforms holds great potential in becoming an important and valuable component in affinity-based high-throughput proteomic screenings as it allows to narrow down the number of discovered targets prior to orthogonal, uniplexed validation approaches. To study whether alphavbeta6 may drive invasive behavior we have used transfection and retroviral infection to create a panel of epithelial cell lines expressing various levels of alphavbeta6. To understand the mechanism of Dok-5 gene expression and regulation during cardiomyocyte differentiation, we first mapped the transcription start site of the mouse Dok-5 gene and characterized its promoter actos common dosage regions. In male specimens this circular smooth muscle extended into the proximal urethra as far as the entrance of the ejaculatory ducts. The effect of nutritional factors on lipid peroxidation in the microsomes of rats of varying ages. A time-dependent increase in SOD and catalase activity was observed. Prevention of bone loss by estradiol valerate combined with medroxyprogesterone acetate among postmenopausal women with osteopenia.

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For that purpose, during 2008, we collected human fluids and tissues from five forensic autopsies following fatal PQ poisonings. The protein complement of the glycerol-grown cells resembled that of the lithoautotrophic cells. Multiple cis-acting elements of the proximal promoter region are required for basal level transcription of the H1(0) histone gene. In this paper, we propose a method for detecting alterations in the Ensemble Spontaneous Activity (ESA), a random signal representing the composite spontaneous contribution of the auditory nerve recorded on the round window. Archival formalin-fixed normal and malignant breast specimens were investigated by histology, in situ PCR with confirmation of the findings by standard PCR and sequencing of the products, plus immunohistochemistry to identify HPV E6 oncoproteins. The circular dichroism (CD) of chromatin below 250 nm is due to DNA and protein peptide chromophores.

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HTLV-I-specific cytotoxic T lymphocytes in the cerebrospinal fluid of patients with HTLV-I-associated neurological disease. The other materials resulted in max concentration of approximately 1 microg/m3 of DEHP and low emissions of DBP. Admission procedures at the College of Osteopathic Physicians and Surgeons. Neovascular glaucoma without peripheral anterior synechiae developed between one and five weeks following CRAO onset. The purpose of this paper is to describe a multi-centre team grant in pediatric emergency medicine (PEM) that has been recently funded by the Canadian Institutes of Health Research (CIHR). By one month, the noradrenaline had decreased and the adrenaline had increased to their initial amounts and proportions. Severe cases may require dialysis: peritoneal dialysis is used in most cases, but extracorporeal methods, including intermittent hemodialysis, hemofiltration and hemodiafiltration, are possible. Endodontic medications are administered directly to the teeth in relatively high concentrations and chemical agents applied to enamel or dentin can penetrate the dental pulp tissue and circulate through the body in the bloodstream. What Can the Dental Health Worker Teach Regarding Nutrition and Diet?. Using problem-based learning (PBL) online is a method by which computers can become a tool to encourage active learning among students.

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Massively parallel bisulphite pyrosequencing reveals the molecular complexity of breast cancer-associated cytosine-methylation patterns obtained from tissue and serum DNA. The effect of the partial pressure of O2 in arterial blood on O2 consumption by patients during artificial circulation. Answering this question might contribute to a better understanding of the different functions of the two systems. In this study, the growth properties of the human chondrosarcoma cell line HCS-2/8, its response to transforming growth factor (TGF)-beta isoforms 1, 2, and 3, and its expression of TGF-beta receptors I and II were examined. Disabled Living Activities Group of the Central Council for the Disabled. Chemopreventive effects of nimesulide, a selective cyclooxygenase-2 inhibitor, against PhIP-induced mammary carcinogenesis. A university-affiliated Department of Veterans adalat gits generic name Affairs medical center.

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Thresholds tended to decrease more at the higher end of the masker contrast range. As a direct result, we discovered that the treatment greatly reduced the size of tumor, and we consider that this treatment prolonged the patient.s life. Neutralizing activity of human antibodies against the structural protein of human T-cell lymphotropic virus type I. To investigate the expression changes of acyl-coenzyme A: cholesterol acyltransferase 1 (ACAT1) on Chlamydia pneumoniae ( induced foam cell formation. Effects of cycloheximide, brefeldin A, suramin, heparin and primaquine on proteoglycan and glycosaminoglycan biosynthesis in human embryonic skin fibroblasts. The cytoplasmic distribution of cellular structures is known to depend on the balance between plus- and minus-end-directed motor complexes. Time-effect profile of antihypertensive agents assessed with trough/peak ratio, smoothness index and dose omission: an ambulatory blood pressure monitoring study with trandolapril vs. Black girls had lower triglycerides and higher HDL cholesterol than White girls. It is estimated that 350,000 children are abducted by members of their families annually.

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Binding of vinblastine in vitro to ribosomes of Sarcoma 180 cells. Contrary to the above findings, fatty acid synthesis from acetate-l-14C by the liver preparations showed a decreased incorporation between the fourth and twelfth hour following irradiation. A simple technique for estimating glomerular filtration rate with subcutaneous injection of (125I)lothalamate. The bioassay showed that the antimicrobial properties may be attributed to astilbin, a flavanone derivative identified on the basis of its spectroscopic data. In application to spectral estimation the rhinocort aqua dose AR model is compared to the classical modified periodogram method. This mixed experimental-simulation approach enabled us to decode the dynamics of the cytostatic and cytotoxic responses to cisplatin and doxorubicin treatments in a p53--proficient colon carcinoma cell line (HCT-116) and in its p53-deficient counterpart. Failure of anaesthesia after accidental subdural catheter placement. Cross-sectional imaging of extranodal involvement in abdominopelvic lymphoproliferative malignancies. Towards the control of individual fingers of a prosthetic hand using surface EMG signals. The genealogy of sequences containing multiple sites subject to strong selection in a subdivided population.

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PUBLIC HEALTH NOTES: STATE AND PROVINCIAL HEALTH AUTHORITIES OF NORTH AMERICA MEET IN WASHINGTON, D. This suggests that under conditions of hypophosphatemia, 1,25-dihydroxyvitamin D3 can mobilize bone in the absence of parathyroid hormone. Enhancement of corticothalamic activity in a cortical column facilitated whisker-evoked responses in topographically aligned thalamic barreloid neurons, while activation of an adjacent column weakly suppressed activity at the same thalamic site. The role of specific agricultural pesticides in relation to adult and childhood cancers has not been firmly established due to the lack of precise exposure data in previous studies. In array painting, chromosomes are flow sorted, fluorescently labelled and hybridised to the microarray. The feasibility of this approach, curative resection rates, patient survival, and patterns of failure were assessed. These data demonstrate that nanoC(60), in contrast to its potent anticancer activity in vitro, can potentiate tumour growth in vivo, possibly by causing NO-dependent suppression of anticancer immune response. D-lactate encephalopathy is a rare cause of recurrent confusion which could be suspected based on a characteristic association of clinical signs. With many predictors, choosing an appropriate subset of the covariates is a crucial, and difficult, step in nonparametric regression.

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