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Alparazole (Alprazolam)

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Alparazole is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alparazole, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alparazole is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alpra, Alprazolam, Alprocontin, Alzep, Alzokam, Alzoset, Anxigo, Anxigon, Betapax, Cooltime, Emlol, Fludep, Fluzolam, Jolistar, Nexlpra, Parazolam, Rozin, Sinozol, Sozox, Tancalm, Tensyn, Trika, Trustin, Xycalm, Xylonite, Zoldac, Zolent

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Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alparazole dosage information


If you have been prescribed Alparazole for medical reasons, the best way to avoid a Alparazole overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alparazole consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alparazole XR dosage information

Side effects

The most common side effects associated with Alparazole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

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This paper shows that the KAERI lung counter probably cannot detect an intake of Type S natural uranium in a worker with a chest wall thickness equal to the average value (2.7 cm) under routine counting conditions. Total serum protein and protein pattern among healthy Northern Nigerians. Due to the calcium-dependent binding of levosimendan to troponin C, the drug increases contractility without negative lusitropic effects. Melittin was very effectve against all strains except Serratia and one Pseudomonas isolate which were partially affected. Origin of epidemic clones of acinetobacter in the critically ill.

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Here we report the survey of the surface of MNEI, a single chain monellin, by means of a paramagnetic probe, and a direct assessment of bound water based on an application of ePHOGSY, an NMR experiment that is ideally suited to detect interactions of small ligands to a protein. Thirty volunteers were enrolled and be subjected to high-speed spiral CT for getting the data of C3-C7. Menthol: effects on nasal sensation of airflow and the drive to breathe. While mast cells and basophils constitutively express the high-affinity IgE receptor (Fc epsilon RI), it is absent or weakly expressed on APCs from normal donors. Tacrolimus, but not cyclosporine A, significantly increases expression of ICAM-1 and IFN-gamma in the NOD mouse. We present a series of 25 patients with extratruncular venous malformations of the skin or the neighboring mucosa that are arranged in a segmental pattern.

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Chromatin-free synaptonemal complex in whole mount preparations. This study aimed to assess dietary information use among persons with chronic disease by using a nationally representative sample of the US population. The distribution and dynamics of LFA-1 molecules over the surface of human lymphocytes were analysed using immunogold label-fracture and fracture-flip methods. These results demonstrate that this phenanthrene (and 9,10-dihydrophenanthrene) scaffold warrants further study as potential selective estrogen receptor modulators and/or pure antiestrogens. Electrical activity was recorded in fasted as well as fed conditions through silver wire electrodes implanted along the entire length of the small bowel. Thus, depending on available equipment and operating budgets, there are at least two high-sensitivity alternatives to achieve the best currently available in-gel protein detection: Sypro Ruby or Coomassie Blue. Studies on preventive and curative effects of berberine on chemical-induced hepatotoxicity in rodents. Increase of circulating endothelial progenitor cells in patients with coronary artery disease after exercise-induced ischemia. Adjunctive olanzapine yielded greater and earlier reduction of manic and depressive symptoms in mixed-episode patients with inadequate response to at least 2 weeks of divalproex.

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Family cancer caregiving and negative outcomes: the direct and mediational effects of psychosocial resources. Sequence and structural diversity in endotoxin-binding dodecapeptides. Effects of cerebrospinal fluid acidity on cerebral blood flow and autoregulation in rats. Paraplegia caused by extraspinal metastasis from a uterine fibroid. Factor analysis in the evaluation of the relationship between bacterial adherence to biomaterials and changes in free energy.

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Whites were designated as high EE significantly more often than were Latinos/Hispanics, regardless of assessment method. To determine the prevalence of abnormal glucose homeostasis and cardiovascular risk factors in youth with acanthosis nigricans (AN). The data from this evaluation continue to support the notion that elevated foot pressure is an important risk factor for foot complications. A hallmark of the disease is increased absorption of iron by the intestine. The hypothyroid responsiveness to LPS, however, was restored upon reconstitution with mast cells derived from the bone marrow of wild-type donors. We induced the passive reverse Arthus reaction to IgG immune complexes (IC) at different tissue sites in mice lacking C3 treated or not with a C5aR-specific antagonist, or in mice lacking mast cells (Kit(W)/Kit(W-v) mice), and compared the inflammatory responses with those in the corresponding wild-type mice. Posttranslational modification by UV filters is a key event in human lenses that appears to be largely responsible for normal age-dependent yellowing.


The mediators and molecular mechanisms regulating muscle IL-6 production are poorly understood. The high affinity of hCA II isozyme towards some sulfonamide inhibitors obtained here was used to select from the dynamic library specific inhibitors of this isoform. Occupational health nursing in Thailand is currently undergoing intensive development in education, practice, research, and legislation. The age of alcohol onset and alcohol, cigarette, and marijuana use patterns: an analysis of drug use progression of young adults in New York State. This study explores the roles of benevolent sexism (BS), hostile sexism (HS), and gender-role traditionality (GRT) in minimizing rape, blaming the victim, and excusing the rapist.

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Both segments--the anterior and posterior one have been taken under consideration. A commonly used extraction method was used as a reference method. Ischemia in vitro significantly increased endothelial cell beta1 expression, which is consistent with the increase in beta1 transcription by microvessels peripheral to the ischemic core. Thus, it is suggested that, at least on a charged surface, a non-helical DNA duplex can be the preferred structural isomer under standard biochemical conditions. Spontaneous cerebral embolism in a forty year old man: case report and review of the literature.

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This article reports the ultrastructure of the aortic lining during the repair of mechanically denuded aortic intima in the rat. Incidence of early adverse events surrounding direct current cardioversion of persistent atrial fibrillation. The EPO-deficient eosinophils of these subjects met the main criteria established for EPO deficiency: absent or strongly decreased reaction for peroxidase, absent or strongly decreased staining with Sudan Black, and an increased ratio of the granule core volume to the total granule volume. Hypoxic dilation of gracilis arteries was severely impaired by either endothelium removal or cyclooxygenase inhibition with indomethacin, but not by nitric oxide synthase inhibition with L-NAME. We demonstrate the existence of a stable black self-guided beam of circular symmetry in a bulk self-defocusing Kerr medium. Noncovalent PEGylation of cationic particles via PEG-avidin/biotin-PEI is an attempt to bridge the gap between the positive attributes of PEG (prolonged particle circulation) and the positive attributes of nontoxic cationic polymers (enhanced cell interactions) for greater gene expression. The experiments demonstrate a significant increase in gene and protein expression of type 1 hexokinase in glomeruli of diabetic rats throughout a three week observation period. We assessed the diuretic effect of four traditional Vietnamese herbal remedies from Zea mays, Imperata cylindrica, Plantago major and Orthosiphon stamineus, all claimed to produce an increase of diuresis. One hundred and twenty-five consecutive ports in 123 patients were evaluated retrospectively. Event probabilities, and frequency and dose-averaged deposited energies are calculated with and without scattering contribution and compared.

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The growing denials of patient-care costs related to clinical trials serve to threaten patient access to potentially efficacious therapy. Adolescents are at risk for developing a variety of sexually transmitted infections for many reasons. Bosentan acutely and during short-term oral therapy markedly improved hemodynamics in patients in addition to standard heart failure therapy, including an ACE-inhibitor. Two research questions are investigated: (i) To what extent are firm characteristics associated with the importance of measurement of various categories of EPIs?. Synthesis and evaluation of a new polymer-supported pseudoephedrine auxiliary for asymmetric alkylations on solid phase. To investigate the reproducibility of these measures, iontophoresis was carried out twice at one site after a 50 min interval and once at another site on the forearm of 16 healthy females. Changing the order of a set of markers and/or the distances between the markers can make a substantial difference in the resulting lod score curve and the location and height of its maximum. Our study aims at assessing the effects of different levels of CVP in relation to type of vascular control on perioperative blood loss and patient outcome. Niravoline is a selective agonist of kappa-opioid receptors having potent aquaretic activity which may peripherally be mediated in animals. Integration of a contactless conductivity detector into a commercial capillary cassette.

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We report creatine kinase (CK) and CK-MB values during a cycloergometric test up to maximal work capacity in 10 normal subjects aged 20 to 39 years (mean body mass index, 22 kg/m2) and 11 obese patients aged 17 to 42 years (mean body mass index, 41 kg/m2), all without any cardiorespiratory diseases. Pigmented vascular lesions such as angioma or watermelon stomach are ideally suited for laser therapy using a wavelength preferentially absorbed by hemoglobin. LABORATORY: A YEAST EXTRACT MEDIUM FOR DETERMINING THE BACTERIAL CONTENT OF MILK BY THE PLATE METHOD. Estimated fumonisin exposure in Guatemala is greatest in consumers of lowland maize. Analysis of fractal dimension of O2A glial cells differentiating in vitro. However, research efforts focused on biomarker validation and implementation clearly lag behind those directed toward initial biomarker discovery. Feather mites and birds: an interaction mediated by uropygial gland size?. Discovery and expository methods in teaching visual consonant and word identification. Strain 4481 was the least variable and did not change in any of our tests.

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Degenerating somas (neuronal death) and axonal/synaptic endings (terminal degeneration) were depicted by a silver technique, and functionally affected cortical neuronal subpopulations by Egr-1, c-Fos, and FosB/DeltaFosB-immunolabeling. Reduced CFR could potentially cause subendocardial ischemia during conditions of high metabolic demand, such as uncontrolled hypertension and tachycardia. Control of cross-infection by formaldehyde disinfection of blankets. Increase in alveolar nitric oxide in the presence of symptoms in childhood asthma. The submicrometer fiber generation of the grafted material is clearly demonstrated through scanning electron microscopy. MBL was observed as an unexpected finding when blood samples were immunophenotyped by two-colour flow cytometric methods in common use at that time. The effects, for example, of turning from a predominantly hospital-based service to one which depends on the co-ordination of a large number of smaller community agencies, are potentially much greater than anything that could be expected from the introduction of a new drug. Epidemiology and prevention of acute rheumatic fever in childhood. Administration of prednisolone at 40mg/day reduced coreg 12.5 pill the symptoms and EDTA-dependent pseudothrombocytopenia, and EDTA-dependent anti-platelet antibody disappeared. Treatment of pressure on the spinal cord from destructive extradural processes.

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Daytime symptoms and sleep diary information were then collected for 1 week on hand-held computers. Participants completed a forced-choice written survey consisting of demographic information and statements assessing the impact of teaching. We also demonstrate considerable isoform diversity of both hc-Rel and p105. In this review, a comprehensive account of the advances in the development of animal models for FBD and FDD and of their relevance to the study of Alzheimer disease is presented. Childhood urinary do i need prescription to buy ventolin infection associated with vesico-ureteric reflux. It is circular, like those of the pathogenic actinomycetes Mycobacterium tuberculosis and Corynebacterium diphtheriae, but unlike the linear chromosomes of the model actinomycete Streptomyces coelicolor A3(2) and the closely related Streptomyces avermitilis.

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Application of percolation model to the tensile strength and the reduced modulus of elasticity of three compacted pharmaceutical excipients. zPicture also facilitates transcription factor binding-site analysis via the rVista tool portal. For the 78 patients who underwent anatomic repair, postoperative echocardiography showed that tricuspid incompetence disappeared in 65 patients and was mild in 13 patients. Distinct effects of surgical denervation on hepatic perfusion, bowel ischemia, and oxidative stress in brain dead and living donor porcine models. It must be regarded as a biological treatment that works by changing the brain and is therefore just as important as depakote false positive drug test pharmacotherapy in terms of overall treatment planning. Hence, prospective data collection is essential to accurately characterize these variations and to properly interpret results from contraceptive trials and other studies concerned with fecundability and hazards of reproduction. To compare first-time parenthood probability and pregnancy outcome between cancer patients and the general population. The whey-acidic protein human epididymis protein 4 (HE4) is frequently overexpressed in ovarian cancer, suggesting that the HE4 promoter is highly transcriptionally active in the disease.

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However, the possible role of thiocyanate, which is also an anion, has not been established yet. Nevertheless, there are only a couple of genes the role in ovary development of which has been described till now. The present study was undertaken in an attempt to clarify the effect of PG on pituitary-thyroid axis in vivo. Ultraviolet B-induced phosphorylation of histone H3 at serine 28 is mediated by MSK1. We suggest the one-hand type power-assisted wheelchair for persons with hemiplegia. The circadian factor that integrates this dual function of heme is not known. A significant number (30 percent) of mice receiving both endotoxin and modified cells rejected a subsequent implant of viable tumor cells. Ghrelin is a novel neuroendocrine signal possessing a wide spectrum of biological activities that illustrates the importance of the stomach in providing input into the brain. In situ hybridizations of deparaffinized human lung tissue slices derived from wt-CFTR or CF patients also showed downregulation of ND4 in CF. These results emphasize that computational enzyme designs will benefit from considerations of dynamical fluctuations when optimizing active site geometries.

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The model quantitatively simulates human psychophysical data about visually guided steering, obstacle avoidance, and route selection. For the infertile couples, no abnormality had been detected by conventional semen analysis, postcoital test of sperm motility, endometrial biopsy, or laparoscopic dye insufflation of the fallopian tubes. Only subtle age changes could be demonstrated with the rotational and caloric tests, in contrast to more pronounced age trends with the VEMP. Chemotherapy resulted in complete resolution of the paranasal mass. The data were used to construct separate structural equation models explaining the influence of stress and social resources on well-being in the two groups. The effects of brief applications are reversible, but responses to subsequent applications of PAF are substantially reduced. By using automated solid-phase extraction coupled to isotope dilution-high-performance liquid chromatography-tandem mass spectrometry, we analyzed 2,094 serum samples collected from NHANES 2003-2004 participants. In pit1 mutants, the total number of gsualpha-positive cells is normal despite the loss of gsualpha and tshbeta coexpressing cells. A questionnaire was designed and posted to all PCOs in England in order to identify the number that had provided or were presently providing a PDVS and determine the nature of the services. These technical details are discussed and typical applications given.

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We show that serine 2015 of CBP and serine 89 of p300 are necessary for PE to stimulate the transcriptional activity of these proteins. Gel filtration-FPLC studies revealed 1 peak of NT-proBNP (approximately 25 kDa), 1 peak of proBNP (approximately 37 kDa), and 2 peaks of BNP immunoreactivity, a major peak (approximately 37 kDa) for proBNP, and a minor peak (approximately 4 kDa) for BNP. Proceedings: A method for the quantitative determination of the antithrombin III (AT III) activity in plasma and serum using the complex formation with heparin. Rapid induction of neurotrophin mRNAs in rat glial cell cultures by Semax, an adrenocorticotropic hormone analog. Several studies have examined if ST use increases the risk of smoking initiation, but few have modeled this complex behavior appropriately. This arcoxia 60 mg harga facilitates further studies of the function of CEA at the molecular level. Twenty-nine parents, 42 teachers, and 37 referrers provided reports on a series of child, parent, and family functioning measures. Tunicamycin neither modified the topoisomerase levels nor inhibited the ATM activation caused by camptothecin and etoposide. Acellular pertussis vaccines were recently introduced in Canada based on evidence of improved safety and efficacy over whole cell vaccines, the current standard of care. However, no direct evidence for the class I-dependent association of CD8 and the TCR has been demonstrated.

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Replication arrest is mediated by protein-DNA complexes that show polarity of function: they arrest DNA replication from one direction only. Transdermal application of bupivacaine-loaded poly(acrylamide(A)-co-monomethyl itaconate) hydrogels. Insects have a family of 12 peptidoglycan recognition proteins (PGRPs) that recognize peptidoglycan, a ubiquitous component of bacterial cell walls. Esterification of pABA may eliminate such errant behavior and provide a readily reclaimable storage form of pABA as well as a substrate for membrane transporters. Electrophoretic investigation on blood proteins in dementia paralytica.

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We evaluate the evidence that depression, anger, hostility, and anxiety are related to risk for the metabolic syndrome, focusing as well on its components of central adiposity and insulin resistance. Synthesis of a non-natural T-antigen containing glycosphingolipid. Mortality from cancer of the breast in Great Britain and the Netherlands. To investigate whether hyponatraemia develops in hypothyroid status by examining sodium handling in screening-detected neonates and infants with congenital hypothyroidism (CH). Furthermore, the decondensation of pericentric heterochromatin did not result in transcriptional reactivation of silent genomic elements. Dutch cardiac surgery centers lack consistency in management with respect to the prevention of postoperative constipation. Benzodiazepine prescription practices and substance abuse in persons with severe mental illness. Senescence was shown to affect the glycosylation profile of endogenous proteins. Two patients had chronic cholecystitis and biliary colic resulting in weight loss and multiple admissions. Transcription initiation of human Oct-1 transcription factor-encoding gene involves two promoters, 1U and 1L, located at a substantial distance (about 100 kb) apart.

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Laboratory efficacy of metabolites of Lagenidium giganteum (Couch) on Anopheles stephensi (Liston) after filterations by Column Chromatography. Relationship of allergy and infection to secretory otitis media. Abstract We report the successful use of an embolectomy catheter to retrieve a metal bullet tip of a cardiotomy suction device that was lost during redo coronary artery surgery. Synthesis and antiinflammatory activity of some 2-heteroaryl-alpha-methyl-5-benzoxazoleacetic acids. It was concluded that concentrations of urea in the serum of the cows were reflecting dietary protein intake and that concentrations of albumin, haemoglobin and PCV during lactation were affected by long-term protein status. Several factors assumed to be responsible for the formation of the false aneurysms 7 years after the previous grafting operation are discussed. This model requires close communication between the therapeutic apheresis medical director and the referring clinician.

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In 12 specimen we found disorders of the spine and the extremities. Lung cancer occurring in women displays some specific epidemiological, radiological, clinical and pathological characteristics. Ultraviolet-induced pyrimidine dimers in long pyrimidine tracts from L-cell DNA. We explored the temporal dynamics of parietal and prefrontal cortex involvement in verbal working memory employing single-pulse transcranial magnetic stimulation (TMS). To investigate effects of riluzole on the kindling development, rats were stimulated once daily for the drug session of 14 days at a imipramine medicine current of 200 microA, 60 Hz, 1 ms for 2 s and thereafter stimulated without drugs (drug-free session) until completion of kindling. DNA vaccination is an effective means of protecting experimental animals against infectious pathogens and cancer and has more recently been used to prevent autoimmune disease. Finally, we argue that although greenbeards are likely to be most common and easiest to detect in microorganisms, they are unlikely to important in organisms such as humans. Recent reports suggest that sialidase may be involved in intimal thickening, an early stage in the development of atherosclerosis.

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If this hypothesis beli albendazole tablet applied in this model, blockade of the type 2 receptor should exacerbate radiation nephropathy and/or counteract the beneficial effects of type 1 receptor blockade. The LD50 of subcutaneously (sc) injected daunorubicin alone (14.0 mg/kg, q4d times 3) was not increased by concomitant ip treatment with ICRF-159. This study demonstrates durable vessel patency to 4 years for long Transatlantic Inter-Society Consensus class C and D lesions treated with the Viabahn stent-graft. It also outlines the satisfaction of villagers with Nurse Practitioners and the extensive scope of practice undertaken by these practitioners. The connections from CBI-2 to the buccal ganglia neurons showed a prominent facilitation.

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