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Alfresh (Alprazolam)

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Alfresh is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alfresh is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alfresh may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Alcalm, Alltop, Alprocalm, Alpronit, Alzomax, Alzorix, Depten, Endep, Finezol, Fludep, Kurelam, Mebaspa, Notens, Orten, Ozolam, Prosanti, Resta, Resto, Rezolam, Stresnil, Unixl, Viprax, Xylonite, Zeecam, Zepro, Zocam, Zolorel

Similar Products:
Rogaine, Amoxil, Ambien, Acticin, Fasigyn, Loracalm, Normatine, Flutrol, Silicof, Benformin, Azicip, Elrip, Benzys,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alfresh. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alfresh XR dosage information

Side effects

The most common side effects associated with Alfresh are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

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CIAS1 mutation in a patient with overlap between Muckle-Wells and chronic infantile neurological cutaneous and articular syndromes. Clearly, the increased incidence of hypoglycemic incidents following intensive insulin therapy indicates a need for understanding the underlying molecular mechanisms of the acute development of insulin resistance, which will allow a more targeted approach to treat altered glucose metabolism of critically ill patients. Perspectives on public awareness of stroke and aphasia among Turkish patients in a neurology unit. Seven IgHV gene families were respectively amplified by PCR and directly sequenced in 108 childhood ALL. Measurements of miniature EPSPs suggested that synaptic inputs to layer 2/3 pyramidal neurons were altered at the junction of deprived and spared cortex in primary somatosensory cortex. Delayed onset of changes in soma action potential genesis in nociceptive A-beta DRG neurons in vivo in a rat model of osteoarthritis. oscillations and damping, depending on only two parameters, namely the time constant of the mechanical respiratory system and a cumulative interaction index. The protocol did provide a good guideline for decision-making for those under ECMO support necessitating bridge to transplantation. A change seemed to be a matter first of vocabulary, then of tentative acceptance, followed by gradual integration into the culture.

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Neutrophil adhesion molecule expression in familial Mediterranean fever: discordance between the intravascular regulation of beta2 integrin and L-selectin expression in acute attack. Implantation was done subperiosteally in bilateral palatal grooves in 34 male Wistar rats divided into three age groups: a 10-week-old group (10w group), a 30-week-old group (30w group) and a 70-week-old group (70w group). Total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), triglycerides (TG) and body composition were measured at baseline and after 3, 12 and 24 months of GHRT. Isolating infected patients has been shown to be effective but can be tricky to achieve. BHA at 0.75 mM caused nuclear condensation and fragmentation, structural damage in mitochondria, decrease in mitochondrial transmembrane potential, and internucleosomal DNA cleavage. Identification of deletion/duplication mutations in DMD gene by multiple ligation probe amplification and denaturing high-performance liquid chromatography. Gastroesophageal reflux disease symptom scores and quality-of-life scores for patients undergoing redo fundoplication are lower than the scores of patients having primary fundoplication.

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Efficacy of amitriptyline as a pharmacological adjunct to behavioral modification in the management of aggressive behaviors in dogs. We therefore studied the effects of HIV and TNFalpha on MMP-2, MMP-9 and their inhibitors, TIMP-1 and TIMP-2, in astrocytes, by zymography and ELISA, respectively, or by RT-PCR for both of them. Perioperative mortality, morbidity, and functional evaluation based on the parameters of speech and swallowing were analyzed. Impairment of the HS-binding activity of gC by these mutations had profound consequences for virus attachment and infection of cells in which amounts of HS exposed on the cell surface had been reduced. Based on our finding of low-specific activity and a fast decay rate for a FVIII point mutation of Glu1829 to Ala (E1829A), we examined whether residue Glu1829 in the A3 subunit is important for A2 subunit retention.

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Regional surveillance of occupational percutaneous and mucocutaneous exposure to blood-borne pathogens in health care workers: strategies for prevention. A comparison of noninvasive objective and subjective measurements of the optical density of human ocular media. This retrospective analysis compared the generic and innovator bioequivalence measures from 2070 single-dose clinical bioequivalence studies of orally administered generic drug products approved by the Food and Drug Administration (FDA) from 1996 to 2007 (12 y). In this study, we investigated the differential expression of 84 stem cell-related genes in dental pulp cells (DPCs) and periodontal ligament cells (PDLCs) undergoing odontogenic/osteogenic differentiation. US genome project does it the French way, conceding that size matters after all. The other class of striatal projection neurons (M-cells) retain the currently executed component in a cortico-BG-thalamic loop, for which the strong nonlinearity in transitions between up and down states of striatal neurons is crucial.

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Hypothalamic, pituitary, and gonadal reserve and responsiveness were evaluated by clomiphene, LHRH, and HCG tests. Regardless of whether simultaneous or sequential traction is used, the downward traction to the occlusal plane seems to induce intrusion of the molars as well as their distal movement. The shaped holes have a 15 degrees forward expansion with an inclination angle of 35 degrees. The experimental results suggest high efficiency and reliability of the proposed approach. Cytochemistry studies were performed using colloidal gold-conjugated lectins (concanavalin A, glycine max, Ulex europaeus) that reacted with the cytoplasmic components (endoplasmic reticulum, Golgi vesicles). Furthermore, the critical shear-stress also showed good agreement with the threshold shear-stress, as measured in a rotational Couette flow. The effect of ORG 2058 was shown in T-47D cells to be time- and concentration-dependent and resulted in an approximate two-fold increase in PRLR mRNA after 24 hr of treatment with 10 nM or 100 nM ORG 2058. The studies revealed a good correlation of T(h) values with the known effects of pH and excipients on protein stability in solution. Folate, which is found in green leafy vegetables, is involved in C1 group transfer and contributes to purin and thymi-dilate synthesis as well as to DNA methylation.

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Subcutaneous administration of HMG-CoA reductase inhibitors in hyperlipidaemic and normal rats. To evaluate the clinical outcome of craniofacial resection for advanced malignant tumors in oral and maxillofacial regions. Current issues with covariate adjustment in the analysis of data from randomized controlled trials. Surface proteins are potential virulence factors and therapeutic targets, and in this study, we decided to target three genes encoding putative membrane lipoproteins in F. Diffusible fraction of cholesterol in serum of patients with nephrotic syndrome. Past research has associated ABO blood type and mental stress with cardiovascular risk.

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Fractionation of exercise training provided no advantage in terms of exercise adherence, improvements in fibromyalgia symptoms or physical function. GGT may in part be a marker of the oxidative stress associated with ethanol metabolism. For all four soils, the sorption isotherms were linear, and desorption could be described by a model involving three types of sites: equilibrium, nonequilibrium, and non-desorption. The light emitted from the measured LEDs, which are illuminated under pulse current operation condition, is captured by the spectrometer and the human photopic vision detector. Proceedings: Genetic factors in multiple sclerosis: the major histocompatibility system (HL-A) and immunity. These investigations elucidate the neural subsystems supporting musical pitch, melody, harmony, rhythm, tempo, meter, and duration.

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2 had been taking extremely high doses of calcium carbonate for dyspeptic pain. This study is meant to bring attention to the assumptions implicitly made when using Fourier methods. A mammary gland EST showing linkage disequilibrium to a milk production QTL on bovine Chromosome 14. Transanal endoscopic microsurgery (TEM) resection of rectal tumors. We measured DR curves of PaO2/FIO2 versus the inhaled NO dose at regular intervals. Human plasma levels of adriamycin were predicted and comparison with patient data demonstrated a reasonable first approximation.

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Recombinant LycCC (rLycCC) protein produced in Pichia pastoris exhibited marked chemotactic activity for peripheral blood leucocytes (PBLs) from large yellow croaker. Pulmonary disease is usual with Mycobacterium tuberculosis or with mycobacteria other than M tuberculosis (MOTT) and atypical presentations with extrapulmonary dissemination occur frequently. Metronome breathing is employed to provide a sinusoidal input to the neuro-cardiovascular system in which Heart Rate Variability (HRV) and Blood Pressure Variation (BPV) are considered as its outputs. Effectiveness of preoperative sedation with rectal midazolam, ketamine, or their combination in young children. The data do not support the hypothesis linking activin A with impaired trophoblastic invasion of the maternal spiral arteries, placental hypoxia and the release of cytokines which in turn cause endothelial dysfunction and the development of the clinical symptoms of the disease. Observer-dependent variability of quantitative clinical endpoints: the example of canine echocardiography. He was found to have a clinically normal cardiac status and a mass lesion in the anterior mediastinum, probably arising from the pericardium near the right atrium, as shown by both echocardiography and a computerized tomographic scan of the chest. Emergency pulmonary autograft mitral valve replacement in a child. Does the electrocardiographic presence of Q waves influence the survival of patients with acute myocardial infarction?. It is capable of rapid and precise measurements, is non-destructive and non-invasive, can be used on-line or off-line and is relatively inexpensive.

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We speculate that the higher blood pressure in TT homozygous men might arise via a metabolic pathway characterized by obesity and insulin resistance as well as via increased peripheral resistance secondary to the higher haematocrit. In spite of its added expense, increased potential for side effects and questionable efficacy, combination therapy with insulin and a sulfonylurea is often considered in noninsulin-dependent diabetics with difficult-to-control disease. Cellular sequence of tracheal repair in sheep after smoke inhalation injury what antibiotic increases theophylline levels . Aerobiology of the Colorado Rockies: pollen count comparisons between Vail and Denver, Colorado. Immunohistochemical markers of renal tubular injury and cyclosporin nephrotoxicity in kidney allograft biopsies.

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24-hour intragastric pH measurement in the assessment of duodenogastric reflux. The applicant pool includes orthopedic, plastic, and general surgeons, as well as neurosurgeons. The effect of L-NAME and L-arginine on impairment of memory formation and state-dependent learning induced by morphine in mice. VITAL STATISTICS : Constitutional, Statutory, and Administrative Aspects. Strengthening the educational potential of small-group work: implications from the evaluation. We also describe the calibration of the human photopic vision detector. The results suggested that these two dynamical parameters depended also on the field type and the field strength. Symptoms control was good or very good in the most of patients (14). X-ray diagnosis of obstructive uropathies in children with lymphogranulomatosis.

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Correlation between asbestos dust concentration and frequency of radiographic detection of pulmonary asbestosis. In vivo and in vitro experiments have provided important information about how the anatomy and physiology of these cells and this layer fit into the functional cortical circuitry. This work presents an AFM investigation of the cross-section of a cavity generated in human dental enamel by laser thermal evaporation using the Cu-HyBrID laser. A home self-sampling kit is viewed as highly acceptable, but some concerns were raised about collecting and storing faecal matter. Dehydration, clinical and biochemical indicators of inflammation and hemolysis, and, when possible, plasma albumin concentrations should be taken into account when the plasma zinc concentration is used to estimate zinc status during episodes of diarrhea in what does a tramadol pain pill look like childhood.

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CT-myelographic images enabled precise differentiation between myelon, cauda equina and intraspinal tumor. Influence of maternal dexamethasone treatment on morphometric characteristics of pituitary GH cells and body weight in near-term rat fetuses. Rotator cuff tears, Bankart lesions, and superior labral anterior posterior lesions commonly occur in isolation, but there is a subgroup of patients who experience combined injuries. A total of 36 stable renal transplant recipients were evaluated using pulse wave analysis to determine large and small vessel compliance. Global depletion of myocardial norepinephrine and ATP after left coronary artery occlusion in rats.

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Achievements in Mental Hygiene and Promising Leads for Further Endeavor. Effect of banana stem juice on biochemical changes in liver of normal and hyperoxaluric rats. However, humans outlive laboratory models many times over, and only evidence from humans can ultimately identify the drivers of human aging. Electrophoretic separation of environmentally important phenolic compounds using montomorillonite-coated fused-silica capillaries. Several studies show that smoking bans in the home, at school, at work, and in the community are associated with less progression to smoking, less consolidation of experimental into regular smoking, and more quitting among adolescents and young adults. Plants seldom experienced water potentials more negative that -1.5 MPa. We have developed a combined Ti:Al(2)O(3)/Cr:LiSrAlF(6) laser system capable of producing terawatt pulses with a duration of 120 fs at a 1-Hz repetition rate. We report a case of community-acquired pneumonia, caused by Eikenella, in a patient with diabetes mellitus and a past history of testicular cancer.

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