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Alfix (Alprazolam)
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Alfix

Alfix is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alfix is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alfix may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Acalm, Albiz, Alcalm, Allam, Alltop, Alpanol, Alprastan, Alprazan, Alprine, Alpron, Alproz, Alzolite, Alzorix, Anxofit, Anxorel, Anxyl, Apsolam, Azoslip, Belfa, Cozac, Depoxit, Depwell, Endolam, Enxolam, Faxtin, Flumusa, Jolistar, Mediprex, Morecalm, Norex, Onapract, Optizole, Ozolam, Paxor, Plaxid, Pranol, Rescalm, Resto, Romipraz, Serxanti, Somnirest, Tancalm, Xycalm, Zolipax, Zorest

Similar Products:
Ambien, Lioresal, Catapres, Minocin, Asacol, Casodex, Valtrex, Rogaine, Leukeran, Urispas, Clinwas, Alzolam, Biprab, Respid, Acichek,

Also known as: Alprazolam

Description

Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alfix. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alfix XR dosage information

Side effects

The most common side effects associated with Alfix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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In contrast, in the constitutive pathway, newly synthesized protein is not stored but is transported directly to the cell surface and secreted even in the absence of an extracellular signal. This pilot study describes the showering habits of people with brain injury (BI) compared with those of people without BI (WBI). Since mucosal induction of salivary immunity would be preferable in humans, we explored methods to induce mucosal antibody in the rat to the GTF peptide vaccines HDS and HDS-GLU after intranasal administration. At all serum levels, P-e and K-e increased with increasing sterol polarity: desmosterol greater than cholesterol greater than beta-sitosterol. The male proband from Bangladesh presented with randomly distributed hyper- and hypo-pigmented skin lesions of variable shape and size with a mottled appearance. The occurrence of long chain polyprenols in leaves of plants of Rosaceae family and their isolation by time-extended liquid chromatography. The primary complication is hypopituitarism, and the risk of developing new anterior pituitary deficits correlates with the size of the irradiated tumor. Account of a visit to Paris, under the auspices of the Ministry of the Interior, with the aim of perfecting laboratory technics for hormone determinations, many related especially to endocrine problems.

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Atrial fibrillation and atrial flutter appear to be important factors in predicting mortality after myocardial infarction, especially in the elderly, as well as ventricular arrhythmias - sustained ventricular tachycardia and ventricular fibrillation. Additionally, users that met DSM-IV substance use disorder criteria for lifetime MDMA abuse or dependence exhibited a number of additional deficits relative to those who did not meet these criteria. Based on the evidence that lamotrigine added to clozapine in refractory schizophrenic patients has reported promising results, the present 24-week double-blind, randomized, placebo-controlled trial had the aim to explore the efficacy of lamotrigine add-on pharmacotherapy on clinical symptomatology and cognitive functioning in a sample of treatment-resistant schizophrenic patients receiving clozapine. The temporal and spatial regulation of chitin synthesis plays an important role in morphogenesis during fungal growth and development. Information giving, failure and abnormality, professional support, and concerns and outcomes were the themes that emerged from the literature. Non-heme iron is essential for the asexual growth of the human malaria parasite Plasmodium falciparum in mature erythrocytes. Most physical experiments of homeopathic preparations were performed with inadequate controls or had other serious flaws that prevented any meaningful conclusion. However, management of the airway, particularly with regard to long-term reconstruction in children with CHAOS, remains challenging. The aim of this study was to determine the accuracy of HpSA for the diagnosis of H. Human immunodeficiency virus-associated polymyositis: a longitudinal study of outcome.

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After this period, the survival probability of one genotype dropped sharply relative to the other. Time dependence of mortality risk and defibrillator benefit after myocardial infarction. Synthesis of a chiral aziridine derivative as a versatile intermediate for HIV protease inhibitors. Research approaches to address uncertainties in the risk assessment of arsenic in drinking water. These fractions occupied different mass ranges and showed differences in the fine structure of their mass spectra. This review examines the incidence of MSI and its clinical significance in commonly occurring solid malignancies.

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Although overnight contact lens wear should be recommended with caution and carefully monitored for early detection of ocular complications, it appears that high-Dk RGP lenses can be a safe and effective treatment for correction of refractive error for most individuals who can adapt to EW. In vitro adhesion assays with the human intestinal epithelial cell line Intestine 407 indicated that the recombinant lactococcal cells had gained an ability to adhere to Intestine 407 cells significantly greater than that of wild-type L. This study included a total of 225 patients who were diagnosed as having prostate cancer by transrectal needle biopsy and subsequently underwent radical prostatectomy (RP) without neoadjuvant therapy. This pathway is triggered by oxidized proatherogenic lipids, such as oxidized low-density lipoprotein and linoleic acid derivatives, which promote differentiation of CCR2(hi)CX3CR1(lo) human monocytes to CCR2(lo)CX3CR1(hi) macrophages that adhere to coronary artery smooth muscle cells in a CX3CR1- and peroxisome proliferator-activated receptor gamma-dependent manner. Fire as an environmental cue initiating ascomycete development in a tallgrass prairie. DbetaHB prevented the decrease of cell viability and the increase of caspase-3 activity induced by 6-OHDA in a dose-dependent manner in PC12 cells. Some authors report using medical treatment only for diverticulitis. Their structures were established on the basis of extensive spectroscopic (IR, MS, 2D NMR) data analysis and by comparison with the spectroscopic data reported in the literature. Retinas from mice lacking RGS11 (RGS11(-/-)), or with a deletion mutation in RGS7 (RGS7(Delta/Delta)), or both, were compared to wild-type (WT) by immunofluorescence confocal microscopy.

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By transneuronal spread, the virus gains access to synaptically linked neuronal circuits. Clinical results of excimer laser photorefractive keratectomy for high myopic anisometropia in children: four-year follow-up. Variations in the branching pattern of the aortic arch in three Trinidadians. Eight women and nine men aged between 60 and 81 (mean 69) years were recruited through a specialist wheelchair service database. This placebo-controlled trial did not find evidence of a beneficial effect of creatine monohydrate on survival or disease progression in patients with ALS.

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With respect to learning and memory AmGluRA appears to be required for memory formation. The crystal structure of the complex of peanut agglutinin with T-antigen reveals the basis of this specificity. It gives the possibility that the object be seen, localized, sampled and evacuated entirely. Multivariate analysis was used to identify all possible independent prognostic variables. These observations suggest that changes in osmolarity affect the responses of canine bronchi to carbachol and that the epithelium modulates the responses of airway to hypotonic solutions. Shape parameter networks provide an approach for representing shape dependencies and producing multi-object models that share consistent boundary definitions.

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HDL3 (30 microg/mL) induced COX-2 expression in a time- and dose-dependent manner. In addition, it expresses many of the respective endocrine, paracrine and cytokine/growth factor receptors. Although bevacizumab has received most attention for first-line treatment of advanced colorectal and nonsmall-cell lung cancer, there is a rapidly growing body of evidence for its efficacy in treatment of a number of other solid tumors. All researchers submit queries through the same interface and the security module processes the taxonomy and user identifiers to limit access. However, further studies indicated that the effect was primarily attributable to the different light diffusion properties of the films tested. More than half of the patients with AIL that display unfavourable prognostic factors at diagnosis or relapse would be expected to be alive and disease-free after 3 yr when treated with HDC/ASCT. Axonal swelling of a nerve was diagnosed in three patients, direct compromise of a nerve by surrounding scar tissue or surgical implants was diagnosed in 10 patients, a neuroma was diagnosed in three, and insufficient surgical repair, in two. In the recent molecular imaging studies of the magnetic resonance imaging field, in-vivo cell tracking is becoming an issue for the observation of cell therapy and disease behavior. The nuclear localization and phosphorylation of CREB showed a constitutive component that was further induced by the autocrine embryotropin Paf (1-o-alkyl-2-acetyl-sn-glycero-3-phosphocholine). The analytical system could be also used for determination of cysteine and hydrogen peroxide in medicines.

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We discuss here a formalism which allows a first order separation of their effects, and thus, a simultaneous extraction of structural and motional parameters from residual dipolar coupling data. Because many natural poisonous substances are bitter, we conjecture that the mammalian T2R genes are under diversifying selection for the ability to recognize a diverse array of poisons that the organisms may encounter in exploring new habitats and diets. A number of scholars have speculated that religious people will be less likely than others to ascribe either fatalistic or deterministic powers to genes, opting instead to leave freedom as a choice for both God and humans. Similarly, FGF-2 expression was increased in a time-dependent manner. The antibody epitopes were mapped using a variety of recombinant human nephrin variants. Recent molecular biological progress in Marfan syndrome and Marfan-associated disorders. Numerous xenobiotics hamper Sertoli cells junctional communication which is known to participate in spermatogenesis control. The thermal stabilities of these alkylated lysozymes were investigated by differential scanning calorimetry (DSC) at different acidic pH values. The reduction in equivalent dose using the new device compared with the routine procedure ranged from 8.3- to 19.6-fold (mean 14.3-fold) for the fingers of the dominant hand and from 13.6- to 40.3-fold (mean 27-fold) for those of the non-dominant hand (total mean 21.3-fold).

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In the present study, we evaluate the impact of HDL cholesterol on the risk of all-cause mortality in a large population of frail octogenarians and nonagenarians living in a community. Effects of prostaglandin F2alpha on estrous cycle or corpus luteum in mares and gilts. Unlike zwitterionic lipids, stacks of PS bilayers swell indefinitely as water is added. The fish protein diet lowered the 20:4(omega-6) proportion and the ratio of 20:4(omega-6) to 18:2(omega-6) in liver microsomal lipids and phospholipids, which was due to the reduced microsomal Delta6(omega-6) desaturation activity. A review of the English-language literature shows that only 8 cases of facial nerve paraganglioma have been published. A sand column and a two-dimensional sand box were used for the experiments. Healthy Options for Pregnancy and Parenting (HOPP) was a randomized, controlled efficacy trial of an intervention that bypassed the clinical setting. Meta-analysis of risk estimates for prostate cancer among rubber workers. Observations on the systolic I-J stroke acceleration-force values of 49 male subjects from a roller ball-bearing ballistocardiographic bed.

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A randomized trial of exercise treadmill ECG versus stress SPECT myocardial perfusion imaging as an initial diagnostic strategy in stable patients with chest pain and suspected CAD: cost analysis. CBF SPECT images showed higher mean FD values in the VaD group than in the control group, suggesting a difference in the heterogeneity of CBF. PML was once a rare disease, but it is now relatively common among AIDS (acquired immunodeficiency syndrome) patients. The addition of Beringite (a modified aluminosilicate), steel shots (iron bearing material) and organic matter as spoil amendments resulted in changes in arsenate (As) concentrations and pH of spoil material and improved plant growth. A lack of trust was identified as a principal barrier to the use, maintenance, and expansion of the social supports of older adult methadone clients. A rise in the intracellular cyclic adenosine monophosphate (cAMP) level is known to inhibit mediator release. Racial differences in waiting list outcomes in chronic obstructive pulmonary moduretic drug class disease. Chronic myeloid leukemia-associated membranoproliferative glomerulonephritis that responded to imatinib mesylate therapy. Emotional eavesdropping: infants selectively respond to indirect emotional signals. The PES is a multidisciplinary system that can be beneficial to psychiatric emergency patients by providing timely rendering of care, improving access to care, and ensuring safety and better assessment.

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Although some methods have been developed that incorporate pharmacokinetics, these methods do not take into consideration variability in response. To investigate the effect on cerebral oxygenation and hemodynamics of a patent ductus arteriosus with left-to-right shunt during venoarterial extracorporeal membrane oxygenation in a lamb model. By switching Fc domains of a single MAb, we have definitively shown that neutralization in vitro--and protection in vivo in a mouse model--by the human anti-B5 immunoglobulin G MAbs is isotype dependent, thereby demonstrating that efficient protection by these antibodies is not simply dependent on binding an appropriate vaccinia virion antigen with high affinity but in fact requires antibody effector function. Studies of Drosophila metamorphosis have been hampered by our inability to visualize many of the remarkable changes that occur within the puparium. There is convincing epidemiological evidence indicating that the serum levels of high density lipoprotein (HDL) cholesterol are inversely related to the risk of vascular events. Luminance artifacts of cathode-ray tube displays for vision research. A 30-year-old man presenting for routine extraction of a carious upper zithromax 500mg tab left first permanent molar subsequently underwent the retrieval of a palatal root that had been displaced into the maxillary sinus. Cloning of the conserved regulatory operon by its aerial mycelium-inducing activity in an amfR mutant of Streptomyces griseus. Toxicity and blood ammonia rise resulting from intravenous amino acid administration in man: the protective effect of l-arginine. Haemocytes of the cockle Cerastoderma glaucum: morphological characterisation and involvement in immune responses.

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