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Alendronate

Alendronate is used to prevent and treat certain types of bone loss (osteoporosis) in adults. Osteoporosis causes bones to become thinner and break more easily. Your chance of developing osteoporosis increases as you age, after menopause, or if you are taking corticosteroid medications (such as prednisone) for a long time.

Other names for this medication:
Alant, Alendix, Alendronate, Alenost, Bifosa, Denfos, Osteofos, Ostogee, Poronil, Ralenost, Restofos, Zophost

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Description

Generic Alendronate is a drug which helps to fight with postmenopausal osteoporosis, steroid-induced osteoporosis, Pagets disease of bone. Generic Alendronate is a medicine which belongs to the group of medicines called bisphosphonates. Alendronate is also known as Alendronic acid, Alendronate sodium, Ostofos. Generic Alendronate works by preventing bone breakdown and increasing bone density (thickness). Generic name of Generic Alendronate is Alendronate. Brand name of Generic Alendronate is Alendronate.

Dosage

Take Alendronate Plus D exactly as it was prescribed for you. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Alendronate Plus D tablets are taken once each week. Choose the day of the week that best fits your schedule. Every week, take one Alendronate Plus D tablet on your chosen day.

Take the Alendronate Plus D tablet first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine.

Take the tablet with a full glass (6 to 8 ounces) of water. Use only plain water (not mineral water) when taking this medicine.

Do not crush, chew, or suck the tablet. Swallow the pill whole.

After taking an Alendronate Plus D tablet, carefully follow these instructions:

Do not lie down or recline for at least 30 minutes after taking Alendronate Plus D. Do not eat or drink anything other than plain water. Do not take any other medicines including vitamins, calcium, or antacids for at least 30 minutes after taking Alendronate Plus D. It may be best to take your other medicines at a different time of the day. Talk with your doctor about the best dosing schedule for your other medicines.

To be sure this medication is helping your condition, your bone mineral density will need to be tested on a regular basis. You may not need to take Alendronate Plus D for longer than 3 to 5 years if you take it for osteoporosis.

If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using Alendronate Plus D. You may need to stop using the medicine for a short time.

Alendronate Plus D is only part of a complete program of treatment that may also include diet changes, exercise, and taking calcium and vitamin supplements. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture and heat.

Detailed Alendronate Plus D dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Drink a full glass of milk and call your local poison control center or emergency room right away. Do not make yourself vomit and do not lie down.

Overdose symptoms may include muscle cramps, numbness or tingling, tight muscles in your face, seizure (convulsions), irritability, and unusual thoughts or behavior.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alendronate are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Alendronate if you are allergic to Generic Alendronate components. Be very careful with Generic Alendronate if you are pregnant or planning to have a baby, or you are nursing mother. Generic Alendronate can harm a baby. Be careful with Generic Alendronate if you suffer from or have a history of low blood calcium (hypocalcemia), a vitamin D deficiency, kidney disease, an ulcer in your stomach or esophagus. Be careful with Generic Alendronate if you are taking aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Naprosyn, Aleve); cancer chemotherapy; or oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone). Do not stop take it suddenly.

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Enhancement of gama-aminobutyric acid (GABA) and other health-related metabolites in germinated red rice (Oryza sativa L.) by ultrasonication. Transitions in smoking behavior during emerging adulthood: a longitudinal analysis of the effect of home smoking bans. Soil animals are useful indicators of soil contamination, both before and after the bioremediation. Categories with the largest number of faculty members reporting that the needs were major barriers to research activity were: additional personnel, research philosophy, funds, in-service education, information, and space. Postpartum depression, marital dysfunction, and infant outcome: a longitudinal study. Aberrant CLIC4 expression may contribute to the vascular pathology of pulmonary arterial hypertension. An earlier reported series of 1,2,4-thiadiazole-based agonists of FFA1 (GPR40) was evolved into two structurally distinct series of compounds. The serum free light chain (sFLC) has been widely used in the assessment of response in patients with multiple myeloma and other plasma cell dyscrasias. We carried on a the Service Clinical test on patients hospitalization with an indication to inhibit lactation as the Hospital of Gynecology and Obstetrics, Infantil Maternal Institute of the State of Mexico (IMIEM).

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Exploring the use of molecular epidemiology to track bovine tuberculosis in Nigeria: an overview from 2002 to 2004. Acceleration of axonal outgrowth in motor axons from mature and old F344 rats after a conditioning lesion. RT-PCR analysis also confirmed that hSN12W-TERT cells expressed mammalian achaete-scute homolog 1 (Mash1) and Dlx2, genes associated with the development of GABAergic cortical interneurons. We obtained good intraoperative view of the pleural cavity, safe removal of abdominal and pulmonary pathology at the same time, and early repair of the injured pleura with control of hemostasis. Activation in parietal operculum parallels motor recovery in stroke. At entrance and completion of the study the patients completed a 10-cm visual analog scale (VAS) requesting them to rate their pain over the last 24 hours.

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The presence of suspiciousness and even paranoid phenomena may not exclude a diagnosis of AD, but may be related to rejection sensitivity. Recent results have led to the description of root system architectures that might contribute to deep-water extraction or to water-saving strategies. The application of this vector as reported here, an HIV-dependent reporter virus, offers a novel alternative approach to existing methods, in situ PCR or HIV antigen staining, to identify HIV-positive cells. We tested the hypothesis that B7-1 costimulation suppresses pancreatic autoimmunity. Human bladder cancer grown as xenografts and in tissue culture as models of the biology and treatment of invasive bladder cancer. piston flow or exponential) are also applicable for dating based on the decay or accumulation of tracers in groundwater systems. Lowest mass median diameter (MMD) was found for PFOB and varied between the jet nebulizers from 2.2 and 3.7 microm, with a small range in particle size (maximum of 7.3 microm). Isolation and properties of isoleucyl-tRNA synthetase from Escherichia coli MRE 600. The performance of the device is satisfactory and the results are in qualitative agreement with the numerical models. Functional circuitry of a unique cerebellar specialization: the valvula cerebelli of a mormyrid fish.

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Use of the Tailored Activities Program to reduce neuropsychiatric behaviors in dementia: an Australian protocol for a randomized trial to evaluate its effectiveness. There is some relationship between the narrowing of the AVN artery and the increase of interstitial contents in AVN. Injuries reported by ski patrollers were used to estimate injury rates among skiers and snowboarders for the head and neck, trunk, upper extremity, and lower extremity. The College could also strengthen the teaching of professionalism, communication and leadership skills to students, and monitor student training and develop courses that contribute to continuous professional development. The 5 beta-reduction of progesterone (production of 5 beta-DHP and 5 beta,3 alpha-ol) was very active but its 5 alpha-reduction (production of 5 alpha-DHP) was almost absent in the lobus paraolfactorius. Indirect evidence indicates that some of the relevant enzymes are located on the plasma membrane.

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An electron microscopic analysis of the morphology and connectivity of individual HRP-labeled slowly adapting vibrissa primary afferents in the adult rat. This study investigated the menopausal symptoms experienced by women of menopausal age in Ekiti State, Nigeria and the influence on their perceived work ability. This study has been approved by the regional ethics board of Stockholm, Sweden, and it will contribute to the body of knowledge concerning prevention of problem gambling. PEA delayed the post-Golgi transport of albumin but not of transferrin. Albumin-bound fatty acids but not albumin itself alter redox balance in tubular epithelial cells and induce a peroxide-mediated redox-sensitive apoptosis.

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RNase P as a tool for disruption of gene expression in maize cells. The expression of homeotic genes were surveyed with reverse transcription-polymerase chain reaction (RT-PCR) using degenerate primers corresponding to invariant amino acid sequences within the homeodomain and subsequently with specific primers. Distinct P2Y receptor subtypes regulate calcium signaling in human retinal pigment epithelial cells. Overexpression of PTEN abrogated the induction of miR-132 on proliferation, migration and invasion of pancreatic carcinoma cells. This prospective observational study was undertaken to analyze 22 patients with multilevel spinal tuberculosis (Pott disease) who underwent anterior radical debridement, decompression, and fusion using anterior spinal instrumentation and tibial allograft replacement between 1999 and 2001. Efficacy of antibiotics to strains of periodontopathogenic bacteria within a single species biofilm - an in vitro study. To determine the reproducibilities of expert manual outlining and two common automated methods for measuring hippocampal atrophy rates in healthy aging, MCI and AD.

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Commodifying animals: ethical issues in genetic engineering of animals. The PL9R was less cytotoxic, and the hNP showed high loading capacity and colloidal stability. DNA cleavage efficiency of 1 exhibits remarkable increases compared with its ZnII complex and corresponding nonguanidinium compound N-(2-hydroxyethyl)-1,4,7-triazacyclononane and parent 1,4,7-triazacyclononane. Experience in the treatment of trichomoniasis and endometritis in cows. We present a new analysis technique for EEG research on language comprehension, which dissociates superficially indistinguishable event-related potential (ERP) components. One aim is levothyroxine dosage in pregnancy to compare the results to those of a similar study on the enzyme citrate synthase to determine whether a similar domain-locking mechanism operates in adenylate kinase. Selective portal decompression by distal splenorenal anastomosis for the treatment of esophageal bleeding varices in schistosomiasis mansoni. The addition of free-radical scavenger had minimal effect on SbVP formation, therefore the formation of free radicals was probably not the main cause for this effect. The organic polymer matrix in the microsphere-packed column functions to link microspheres at specific sphere-sphere and sphere-capillary contact points.

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