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Aldip (Alprazolam)

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Aldip is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Aldip, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Aldip is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alcicalm, Almac, Alpam, Alpose, Alprac, Alpracon, Alpraday, Alpramax, Alprazan, Altrex, Alzin, Alzoact, Ambusyn, Anxigon, Axizox, Azolam, Balmusa, Berest, Calmef, Censir, Fluwel, Golprax, Imprax, Mebaspa, Mentolift, Pacyl, Plxna, Prozam, Restyl, Samprex, Samrox, Sinaday, Somaspas, Somnarest, Sowel, Tenrid, Xycalm, Zolorest, Zopax, Zopic, Zotam

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Tricor, Sumycin, Antivert, Elavil, Imovane, Valtrex, Robaxin, Xalatan, Prohair, Escitalopram, Frusenex, Zopizone, Mopady,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Aldip. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Aldip XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Aldip XR dosage information

Side effects

The most common side effects associated with Aldip are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: kava, sodium oxybate.Other medications can affect the removal of Aldip from your body, which may affect how Aldip works. Examples include azole antifungals (such as itraconazole, ketoconazole), cimetidine, certain anti-depressants (such as fluoxetine, fluvoxamine, nefazodone), drugs to treat HIV (delavirdine, protease inhibitors such as indinavir), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (such as diphenhydramine), medicine for sleep or anxiety (such as diazepam, zolpidem), muscle relaxants, narcotic pain relievers (such as codeine), psychiatric medicines (such as chlorpromazine, risperidone, amitriptyline, trazodone).Check the labels on all your medicines (such as cough-and-cold products) because they may contain ingredients which cause drowsiness. Ask your pharmacist about the safe use of those products.Cigarette smoking decreases blood levels of this medication. Tell your doctor if you smoke or if you have recently stopped smoking.

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Analysis of the pore of the unusual major intrinsic protein channel, yeast Fps1p. This review covers natural products (secondary metabolites) with reported growth inhibitory activity towards Mycobacterium tuberculosis or related organisms. Enzymes and operons mediating xenobiotic degradation in bacteria. Standard life table techniques were used to decompose the change in the black-white life expectancy gap by combining absolute changes in age-specific mortality with relative changes in the distribution of causes of death. To analyze the results of surgery for velopharyngeal incompetence (VPI) in velocardiofacial syndrome. Natalizumab exerts its immunologic effects by targeting the alpha4 integrin receptor, the site responsible for the migration of leukocytes from the blood into inflamed tissues. The involvement of cyclic adenosine monophosphate cAMP-dependent protein kinase A (PKA) in the regulation of the steroidogenic acute regulatory protein (StAR) and the high-density lipoprotein receptor (HDL-R) genes by steroidogenic factor-1 (SF-1) and cAMP were examined. Dose response of angiogenesis to basic fibroblast growth factor in rat corneal pocket assay: II. Even though recent echocardiography machines store acquired data in a digital format, these data are often not readily accessible to be transferred to a personal computer.

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While anemia is reversible and manageable with transfusions, thrombocytopenia can be a treatment-limiting toxicity. Appendix C specifies the quantities and ranges for which participating institutes recognise the validity of calibration and measurement certificates issued by other participating institutes and these are detailed in the database devoted to these standards and services, commonly referred to as calibration and measurement capabilities. Given the recent surge in obesity, effective dietary strategies for weight management are required. Dominant negative c-Jun inhibits platelet-derived growth factor-directed migration by vascular smooth muscle cells. In an unc-40 wild-type genetic background, some pairs of hypomorphic unc-5 alleles exhibit a partial allelic complementation. The sensitivity of PM detection is limited, even with modern CT techniques. Although the precise mechanism of leukemogenesis of ATL remains unclear, recent progress provides important clues in oncogenesis by HTLV-I. We have studied the ultrastructural characteristics of the pigments in the macrophages of liver and lymph nodes from three children with chronic granulomatous disease (CGD). In early transplants, the contractions were due entirely to surviving muscle fibers in the graft, and the contractile characteristics were those of denervated muscle fibers.

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Laboratory research and clinical findings have indicated that a deficiency in alpha1-antitrypsin is associated with increased risk of liver cancer, bladder cancer, gall bladder cancer, malignant lymphoma, and lung cancer. Overweight and especially obesity, particularly at younger ages, substantially increases lifetime risk of diagnosed diabetes, while their impact on diabetes risk, life expectancy, and diabetes duration diminishes with age. Utricular projections reached the four main vestibular nuclei with a denser accumulation of fibers within ventral parts of the lateral, descending and superior vestibular nuclei. Traffic pollution has been linked with both cardiovascular and cancer risks, particularly in older subjects. Regulation of nod factor sulphation genes in Rhizobium tropici CIAT899. As expected, substrates requiring protonation, such as cis,cis-muconate as well as 2- and 3-methyl-, 3-fluoro-, and 2-chloro-cis,cis-muconate, were not converted at a significant rate by the K169A variant.

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After each laser treatment, hair counts were successively reduced and few patients found it necessary to shave the sparsely regrown hair. These data reveal a considerable plasticity and differential control of regulatory pathways in distinct oxidative stress conditions, providing both specificity and backup for protection from oxidative damage. Since the error term may come into the allometric relation either exponentially or additively, there are at least two methods of estimating the parameters of the allometric equation. A bladder mucosa graft was used successfully for urethral reconstruction to treat posterior hypospadias. PP-G(4)-L may aid in the discovery of additional binding partners of Grb2 family SH3 domains. Persistent neonatal and infantile hyperinsulinemic hypoglycemia (PNHH) is a rare entity which remains to be elucidated but associated with severe lesions in pediatric patients. Findings from a gender study may have utility for the development of differential treatment interventions for men and women and may improve the outcome of the illness in general. This retrospective, nonrandomized analysis evaluated the effect of initiating statin or beta-blocker treatment early in the course of heart failure developed during acute myocardial infarction compared with the effect of neither or both treatments. Further, we showed that, in cultured SK-N-BE(2)C human neuroblastoma cells, overexpression of PLD2 inhibited cell death by chemical hypoxia induced with potassium cyanide and deoxyglucose.

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44 ITI solid screw implants were placed in the grafted sinuses with a mean of 2.75 implants on each side. PE was significantly increased in the microsomal, mitochondrial and plasma membrane fractions, whereas cholesterol was increased in both the microsomal and nuclear fraction. The development of a secondary neoplasm in childhood cancer survivors attains growing importance due to the reported excellent survival and therefore the long exposure to potentially carcinogenic effects of treatment. Primary nasopharyneal tuberculosis is a rare disease which is commonly present with cervical lymphadenopathy. The majority will therefore not benefit from an endoscopic surveillance program, based on the histological identification of dysplasia. Report of the Committee on Professional Education (Proposed Report on the Educational and Experience Qualifications of Laboratory Workers). Cranial computed tomography revealed marked hypodensity in both cerebellar hemispheres and white supratentorial substance with obliteration of the quadrigeminus cisterns. Delayed gastric emptying was documented in 31.0 per cent of patients, but there was no relationship with reflux pattern. Microdiscectomy: spinal anesthesia offers optimal results in general patient population. The approach discussed below aims at monitoring the replication pattern and the kinetics of replication throughout the entire genome of living cells.

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The present study demonstrates that the HO-1/CO pathway inhibits sFlt-1 and sEng release, providing compelling evidence for a protective role of HO-1 in pregnancy, and identifies HO-1 as a novel target for the treatment of preeclampsia. Fluorescent NotI-MseI MS-AFLP offers a safer method of studying the alterations in DNA methylation, and may be applied to the hybridization of DNA microarrays in the future. Although well tolerated, capecitabine, as with all chemotherapy, can require interventions and dose modification. Bayesian statistical modeling offers an alternative approach to frequentist methodologies, and has several features that make these methods advantageous for the analysis of microarray data. By having the images available at the workstation in an organized worklist, this methodology increases the efficiency of the radiologist. In the context of forensic neuropsychological assessments, the professional interaction of law and psychology is viewed primarily as one where the retaining attorney or court dictates its needs to psychologists when resolving legal disputes. Glycoprotein 170 induces platelet-activating factor receptor membrane expression and confers tumor cell hypersensitivity to NK-dependent cell lysis. The use of cholic acid T tube infusion and of the Burhenne catheter has been investigated in the management of gallstones retained in the common bile duct following biliary surgery in 9 patients.

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An important element in achieving high success rates with free flap surgery has been the use of different techniques for monitoring flaps postoperatively as a means to detecting vascular compromise. Radiofrequency facet joint denervation in the treatment of low back pain: a placebo-controlled clinical trial to assess efficacy. In this study we investigated the phosphorylation status of key proteins in the PI3K/AKT/mTOR pathway and the effects of the mTOR inhibitors rapamycin and CCI-779 on neuroblastoma tumorigenesis. Patients were considered monosensitized to this protein in the absence of sensitization to other cross-reacting, plant-derived foods as shown by negative skin prick test (SPT) results with both birch and mugwort pollen. Higher paternal ACR and night to day ratio of ambulatory blood pressure, but not parental hypertension or maternal factors, are associated with microalbuminuria in young adults with Type 1 diabetes. Intraocular pressure elevation is a common occurrence after intravitreal silicone oil injection. The aim of this study was to assess drug-specific cytokine production by means of flow cytometry as an alternative nonradioactive approach which may be more appropriate for routine testing and may provide in addition more information about the pathophysiology of the reaction than proliferation-based assays, like the LTT. Effects of renal sorbitol accumulation on urinary excretion of enzymes in hyperglycaemic rats.

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Synthesis of some new 2,4-disubstituted thiazoles as possible antibacterial and anti-inflammatory agents. All 146 patients in the randomized clinical trial were included in the present analysis. Associations between demographic characteristics, school schedules, activity choices, family functioning, and sleep behaviors were estimated using nationally representative time-diary data from 2,454 children (ages 5.5 to 11.9 years) and adolescents (ages 12.0 to 19.1 years). During the initial stage, the patient underwent an ascending-to-descending thoracic aortic bypass. Celiac disease (CD) is a common condition but often it goes unrecognized because characteristic histopathological abnormalities must be found to confirm the diagnosis. Case studies in public-sector leadership: implementing a metabolic initiative in a community mental health clinic. Verrucomicrobia were associated with the most oligotrophic reservoir and low pH values. To characterize UNC-6 receptor function in vivo, we have examined genetic interactions between unc-5 and unc-40 in the migrations of the hermaphrodite distal tip cells. Chemoprevention of prostate cancer through dietary agents: progress and promise.

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The authors investigated the clinical and biochemical efficacy of millimeter-wave resonance therapy in patients with destructive pulmonary tuberculosis associated with different cozaar 75 mg concomitant diseases. Glial fibrillary tangles with straight tubules in the brains of patients with progressive supranuclear palsy. The chlorohydrins caused significant depletion of cellular ATP in the range 10-100 microM. Symmetrical form was produced across planeometric surfaces but not across stereometric contours. Cholesterol-dependent partitioning of PtdIns(4,5)P2 into membrane domains by the N-terminal fragment of NAP-22 (neuronal axonal myristoylated membrane protein of 22 kDa). bovinus was the species most sensitive to Cd in terms of dry matter production and P. In this work we show that phosphorylation of c-Myb in response to stress led to rapid protein degradation, which occurred via a proteasome-dependent pathway. This paper presents the measured results of a CMOS operational amplifier that can be incorporated with a wireless IOP monitoring system or other low-power application. Patients on PPIs do have an increased bacterial load in the gastric aspirate, with no clinical significant infection.

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It was conducted over 10 sessions and addressed a wide range of issues relating to the management of mentally ill patients, with the use of a variety of teaching methods. Results showed an increased running economy in the external focus condition. These effects were not explained by subjective anxiety, resting physiologic arousal, physiologic arousal preceding the tone trials, or initial physiologic responsivity. A double-blind, placebo-controlled birch allergy vaccination tenormin 50 mg price in pakistan study: inhibition of CD23-mediated serum-immunoglobulin E-facilitated allergen presentation. The association between deaths from myocardial infarction and household size in England and Wales. Articles reviewed included published abstracts, retrospective and prospective studies, and meta-analyses.

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There was no correlation between the pigmentary variations of tinea versicolor and the type of skin, sex, and age of our patients or the duration, recurrence, site, and symptomatology of the lesions. Nicotine dose (0.75, 1.5, 3.0 mg/injection), time out (TO) value after each injection (1-20 min) and FR response requirement (10-1600) were varied in different subjects over consecutive sessions. Each patient was initially scanned using the conventional transvaginal 2D ultrasound method, followed by transvaginal 3D ultrasound, and finally underwent sterilized catheterization to obtain the actual bladder volume. Apolipoprotein E 139-158 peptide increases micellar binding and endocytosis by hepatocytes motrin ib 200 mg dosage . The changes in free amino acid content and distribution produced by microflora are great enough to serve as a good probe for studying the interactions of a limited number of species of microbes in gnotobiotic animals and assign possible specific functions to each species. The patients were a 10-year-old girl with a large soft tissue mass bulging into the left chest, a 12-year-old girl with a right paraspinal mass, a 21-month-old boy with generalized lymphadenopathy and hepatosplenomegaly and a 6-year-old girl with a large bladder mass. The degradation of extracellular matrix showing the increase of MMP-9 in migraineurs may be associated with an abnormality in their blood vessel permeability.

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The implications of this observation with respect to breast carcinoma screening guidelines and thyroid carcinoma treatment guidelines deserve further investigation. In order to determine the grade of rejection, the morphological findings were blindly graded on a scale of 0-4. Endothelin-1 (ET-1) mRNA and peptide levels were increased in the hypertensive lungs of mildly hypoxic FHR compared with the normotensive lungs of normoxic FHR, and of normoxic and mildly hypoxic TMR and Wistar rats. Patients in the total sample and within each bipolar subtype spent approximately half of their time euthymic. Quantitative evaluation of coronary stenosis by coronary magnetic resonance angiography. The animals were killed 2 weeks after the compression procedure. We use the results to estimate the minimum total cost curves for maintaining native vegetation on the landscape and for preventing cheatgrass dominance.

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There are very few data on the adverse effects of multipuncture BCG administration. It is desirable for the family physician, internist, and obstetrician/gynecologist to provide accurate information during preconceptional counseling of these patients. Digitised left ventricular M mode echocardiography did not predict the presence of acute rejection. Our findings indicate that taking plaques of the descending aorta protonix dosing po into consideration may help improve the spectrum of pathologies considered as high-risk sources for brain ischemia. Sexuality in the nursing home, part 2: managing abnormal behavior--legal and ethical issues. Although the general biosynthetic pathway to plant sterols has been defined, the details of the biochemical, physiological, and developmental functions of genes involved in the biosynthetic network and their regulation are not well understood. Telomere length predicts all-cause mortality in patients with type 1 diabetes. Motivation and procrastination: methods for evaluating pragmatic casual information visualizations. Responses of endothelial cell and astrocyte matrix-integrin receptors to ischemia mimic those observed in the neurovascular unit.

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Since BMP-4 promotes skeletogenesis and inhibits thymus development, our findings suggest that TSG acts as both a BMP-4 agonist in skeletogenesis and a BMP-4 antagonist in T-cell development. In the pre-engraftment phase and during chemotherapy only viral-related morbidity was reduced. To investigate the clinical safety and efficacy of two dosages of tolterodine in older patients with symptoms attributable to overactive bladder. cervical vacuum cup for hysterosalpingography: a prospective, randomized, single-blinded study. An integrated morphological and biochemical study of a purified preparation of the succinate and DPNH oxidase system. The mean superior to inferior tendon thickness at the rotator interval was 11.6 mm, 12.1 mm at midtendon, and 12 mm at the posterior edge. To evaluate the effectiveness of the local emergency medical services system in resuscitation of out-of-hospital cardiac arrest and identify areas for improvement. Social validation of goals, procedures, and effects in public health.

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The analysis of this national database shows that data communicated to the MIDs and therefore to the healthcare authorities, are incomplete regarding SAPSII, ICU cordarone medication procedures, treatment intensity, and diagnoses. Synthesis and aldose reductase inhibitory activities of novel thienocinnolinone derivatives. Our study was designed to determine whether adjunctive antidepressant therapy reduces symptoms of bipolar depression without increasing the risk of mania. The expression of human EG-VEGF occurs predominantly in steroidogenic glands. However, it is well known that the investigation of real case studies is a tedious task. Results are illustrated with the analysis of experiments with coupled electronic oscillators. ATP is a chemorepellant for Leishmania and cells treated with atractyloside, an inhibitor of ANT, no longer exhibit negative chemotaxis for this compound. There is limited information on changes in the epidemiology and outcome of patients with asthma admitted to intensive care units (ICUs) in the last decade. The purpose of this in vitro study was to investigate the amount of quadriceps force required to extend the knee during an isokinetic extension cycle before and after total knee arthroplasty. Each beacon was used to measure the phase aberrations over only part of the telescope aperture, a configuration that is suitable for reducing focal-anisoplanatism error.

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