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Aldactone (Spironolactone)

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Aldactone is used for lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions by removing excess fluid and improving symptoms such as breathing problems.

Other names for this medication:
Aldostix, Amifru, Aquamide, Dyamide, Dytor, Fruselac, Frusis, Lactone, Lasilactone, Metolactone, Spilactone, Spiromide, Spironolactone, Spirotic, Torlactone, Tormax, Torsid, Zator

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Also known as: Spironolactone


Generic Aldactone is a perfect remedy, which helps to fight with hyperaldosteronism, hypokalemia, edema, ascites, hirsutism, alopecia (baldness), acne. It can also be used together with other medicines to treat myasthenia gravis, precocious puberty, high blood pressure. Generic Aldactone acts by controlling the level of water and salt and by decreasing the potassium loss from your body. Aldactone is also known as Spironolactone, Spirotone, Spiractin, Osyrol, Spiroctan, Spirolon, Verospiron. It is aldosterone receptor antagonists. Generic name of Generic Aldactone is Spironolactone. Brand names of Generic Aldactone are Aldactone, Spiractin, Spirotone, Spironol, Berlactone, Novo-Spiroton.


Usual Adult Dose of Aldactone for Edema:

25 to 200 mg orally per day in single or divided doses

Usual Adult Dose of Aldactone for Hypertension:

Initial dose: 50 to 100 mg orally per day in single or divided doses

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 25 mg orally once a day assuming serum potassium is less than or equal to 5 mEq/L and serum creatinine is less than or equal to 2.5 mg/dL

Usual Adult Dose for Primary Hyperaldosteronism:

Diagnostic dose:

Usual Adult Dose for Hypokalemia:

25 to 100 mg orally per day

Detailed Aldactone dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store below 25 degrees C (77 degrees F). Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aldactone are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Drinking alcohol can increase certain side effects.

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Avoid a diet high in salt. Too much salt will cause your body to retain water and can make this medication less effective.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

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We present data from the Korean National Health and Nutritional Examination Survey (KNHANES) 2010-11 on the distribution of blood lead levels, and examine their association with iron deficiency in a representative sample of the adolescent Korean population. As expected, HER2/neu-overexpressing tumors with low pAkt had a decrease in DFS. However, the majority of these studies were limited to in vitro testing. Although acute hemodialysis (AHD) can be used to treat such patients, it requires additional equipment, vascular access cannulations, and personnel. Toxicity and carcinogenicity of rotenone given in the feed to F344/N rats and B6C3F1 mice for up to two years.

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Case-control study of viral samples collected from March 1994 to February 2003 from 30 pediatric MS patients, 90 emergency department controls matched 3:1 with the MS patients by year of birth, and 53 healthy control children. Design of sensor node platform for wireless biomedical sensor networks. Peptic ulcer disease risk in chronic kidney disease: ten-year incidence, ulcer location, and ulcerogenic effect of medications. It is suggested that defibrotide stimulates prostacyclin and prostaglandin E2 production by leucocytes or via platelet/leukocyte interactions. We evaluated the expression of COX-2 in 44 cases of high-grade MPNST using immunohistochemical staining and compared the staining results with the characteristics and outcome of the patients.

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To determine whether the effector phase of protection in vivo to the rodent parasite Plasmodium yoelii yoelii requires Fc receptor bearing cells, we passively transferred immune sera into FcR gamma-chain knockout mice. This new economical assay may be easily automated for large scale cytotoxicity testing using cell membrane integrity. The study highlights the urgent need for strategies to spread awareness about diabetes in the general population. Effects of harvest residue and tillage on lesser cornstalk borer (Lepidoptera: Pyralidae) damage to sugarcane. Thus, amicetin is another addition to the list of drugs which may be useful in studying polysome and messenger ribonucleic acid metabolism in vivo. We believe that most remaining mispredictions are due to atypical ribosomal binding sequences used in specific translation control processes, or likely errors in the training data sets. Comparison of the core RNAP:GreB structure with the previously determined structure of core RNAP located the GreB binding site on one face of the RNA polymerase, next to but not in the 25 A-diameter channel of RNA polymerase. Meanwhile, ECA endarterectomy is routinely done during internal carotid artery endarterectomy (CEA). The aim of the present study was to receive feedback on the views of the patients concerning the usefulness of the information obtained immediately from the scan in the management of their problem. Since melting temperature is dependent on concentration of the oligoduplex, various concentrations were used in this study protocol.

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The automatic pilot of the hand is unbalanced by visual neglect. The putative interferon sensitivity determining region (ISDR) in the NS5a region of the hepatitis C ultram cost virus (HCV) was analyzed in 13 interferon alpha (IFN-alpha) treated patients representing genotypes 1a, 1b, and 2b. We used sub-megabase resolution tiling (SMRT) array-based comparative genomic hybridization to screen HL-derived cell lines (KMH2 and L428) and ALCL cell lines (DEL and SR-786) in order to identify disease-associated gene copy number gains and losses. Long-term seizure remission in childhood absence epilepsy: might initial treatment matter?. In an increasing number of radiological sites, 3-T MRI now starts to play the same role for clinical imaging that was occupied by 1.5-T systems in the past.

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Neurotization via the spinal accessory nerve in complete paralysis due to multiple avulsion injuries of the brachial plexus. This proved to be the most effective treatment with the greatest clinical improvement. We failed to detect any reactivity with the peptide of the ectodomain of gp41 of sera harvested after immunization with the various immunogens or after challenge with HIV-1 SF2 or HIV-1 90CR402. We developed a questionnaire and conducted a survey study at two time periods among 200 subjects at six outpatient acupuncture clinics in Beijing, China. Characterization of a conserved rhoptry-associated leucine zipper-like protein in the malaria parasite Plasmodium falciparum. An emaciated, moribund, male blue jay (Cyanocitta cristata) was collected in Georgia (USA) and died shortly after capture. Since 1988, the College of American Pathologists has been offering materials for calibration verification coupled with the surveys for linearity, called the linearity (LN) surveys.

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The persistent changes in the vagina of neonatally DES-exposed mice result from sustained expression of growth factors by ligand-independent transcriptional activation of the estrogen receptor. Google, Google Scholar, PubMed, ResearchGate, OpenDOAR and OAIster were manually checked to assess the OA status of each included article. Isolated intracranial Rosai-Dorfman disease: case report and literature review. Further assets include the network of regional focal points and teams. Electron microscopy of polyheads of bacteriophage T4 prepared by freeze-etching.

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All 125 naturally contaminated beef carcasses surveyed were negative for E. The incidence and progression of all of the features of AMD are known to increase significantly with age. Diffuse cavernous hemangioma of the rectosigmoid colon is revealed as rectosigmoid wall thickening with high signal intensity on T2-weighted MR images. At necropsy, micrencephaly, semilobar holoprosencephaly, polimicrogyria, ocular abnormalities, skeletal anomalies, congenital heart disease, and agenesis of right kidney were also observed. Longer test stimuli evinced reductions in both changing-loudness aftereffects and the associated response scatters. In contrast, lactate concentrations, although high just after administration of pancreozymin, declined to a considerable extent following each injection, rather similar to those of protein or citrate. Here we identify orthologs representative of the major SPL gene clades in annual Arabidopsis thaliana and Mimulus guttatus IM767, and perennial A.

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If the host becomes immunocompromised, autoinfection may increase the intestinal worm burden and lead to disseminated strongyloidiasis. While wild-type vaccinia virus expresses multiple products to inhibit NF-kappaB during infection, the attenuated deletion mutant MVA lacks this ability. We and others have recently ambien dosage size identified hAda3 (human homologue of yeast alteration/deficiency in activation 3) as a p53-interacting protein and enhancer of p53 activity. CD6 activation blocked anti-IgM- induced Bax(alpha) up-regulation and, by doing so, corrected an imbalance in the Bcl-2/Bax ratio that accompanies apoptosis. To understand the mechanism, human tenocytes and polyglycolic acid long fibers were used for in vitro tendon engineering in a bioreactor system for 12 weeks with and without dynamic loading.

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