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Afineday (Montelukast)
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Afineday

Afineday is a leukotriene (loo-koe-TRY-een) inhibitor that is used to prevent asthma attacks in adults and children at least 2 years old. Afineday is also used to prevent exercise-induced bronchoconstriction (narrowing of the air passages in the lungs) in adults and children who are at least 6 years old.

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Also known as: Montelukast

Description

Afineday (montelukast) is a leukotriene (loo-koe-TRY-een) inhibitor. Leukotrienes are chemicals your body releases when you breathe in an allergen (such as pollen). These chemicals cause swelling in your lungs and tightening of the muscles around your airways, which can result in asthma symptoms.

Afineday is used to prevent asthma attacks in adults and children as young as 12 months old. Afineday is also used to prevent exercise-induced bronchoconstriction (narrowing of the air passages in the lungs) in adults and children who are at least 6 years old.

Afineday is also used to treat symptoms of year-round (perennial) allergies in adults and children who are at least 6 months old. It is also used to treat symptoms of seasonal allergies in adults and children who are at least 2 years old.

Afineday is used for allergies, only after other treatments have failed.

If you already take Afineday to prevent asthma or allergy symptoms, do not use an extra dose to treat exercise-induced bronchoconstriction.

Dosage

Usual Adult Dose of Afineday for Allergic Rhinitis:

-10 mg orally once a day Comments: -For asthma, efficacy has been demonstrated when this drug was administered in the EVENING without regard to time of food ingestion. -For allergic rhinitis, efficacy has been demonstrated for asthma when this drug was administered in the MORNING or EVENING without regard to time of food ingestion. -Patients with both asthma and allergic rhinitis should take only one dose daily in the evening. Uses: -Prophylaxis and chronic treatment of asthma -Relief of symptoms of seasonal allergic rhinitis and perennial allergic rhinitis

Usual Adult Dose of Afineday for Asthma -- Maintenance:

-10 mg orally once a day Comments: -For asthma, efficacy has been demonstrated when this drug was administered in the EVENING without regard to time of food ingestion. -For allergic rhinitis, efficacy has been demonstrated for asthma when this drug was administered in the MORNING or EVENING without regard to time of food ingestion. -Patients with both asthma and allergic rhinitis should take only one dose daily in the evening. Uses: -Prophylaxis and chronic treatment of asthma -Relief of symptoms of seasonal allergic rhinitis and perennial allergic rhinitis

Usual Adult Dose for Bronchospasm Prophylaxis:

-10 mg orally once a day at least 2 hours before exercise Comments: -An additional dose should not be taken within 24 hours of a previous dose. -Patients already taking this drug daily for another indication (including chronic asthma) should not take an additional dose to prevent EIB. -A rescue short-acting beta-agonist should be available at all times. -Daily administration for the chronic treatment of asthma has not been established to prevent acute episodes of EIB. Use: Prevention of exercise-induced bronchoconstriction (EIB)

Usual Pediatric Dose of Afineday for Asthma -- Maintenance:

Less than 12 months: Not approved. 12 to 23 months: -One sachet of 4 mg oral granules once a day 2 to 5 years: -4 mg chewable tablet or one sachet oral granules once a day 6 to 14 years: -5 mg chewable tablet orally once a day 15 years or older: -10 mg tablet orally once a day Comments: -Doses should be taken in the evening. -Efficacy has been demonstrated for asthma when this drug was administered in the evening without regard to time of food ingestion. Use: Prophylaxis and chronic treatment of asthma in pediatric patients 12 months of age and older

Usual Pediatric Dose of Afineday for Allergic Rhinitis:

Seasonal Allergic Rhinitis: Less than 2 years: Not approved. 2 to 5 years: -4 mg chewable tablet or one sachet of 4 mg oral granules once a day 6 to 14 years: -5 mg chewable tablet orally once a day 15 years or older: -10 mg tablet orally once a day Perennial Allergic Rhinitis: Less than 6 months: Not approved. 6 to 23 months: -One sachet of 4 mg oral granules once a day 2 to 5 years: -4 mg chewable tablet orally once a day 6 to 14 years: -5 mg chewable tablet orally once a day 15 years or older: -10 mg tablet orally once a day Comments: -Efficacy has been demonstrated for asthma when this drug was administered in the MORNING or EVENING without regard to time of food ingestion. -The time of administration may be individualized to suit patient needs. Uses: -Relief of symptoms of seasonal allergic rhinitis in patients 2 years of age and older -Relief of symptoms of perennial allergic rhinitis in patients 6 months of age and older

Usual Pediatric Dose for Bronchospasm Prophylaxis:

Less than 6 years: Not approved. 6 to 14 years: -5 mg chewable tablet orally once a day 15 years or older: -10 mg tablet orally once a day Comments: -Dose should be taken at least 2 hours before exercise. -An additional dose should not be taken within 24 hours of a previous dose. -Patients already taking this drug daily for another indication (including chronic asthma) should not take an additional dose to prevent EIB. -A rescue short-acting beta-agonist should be available at all times. -Daily administration for the chronic treatment of asthma has not been established to prevent acute episodes of EIB. Use: Prevention of exercise-induced bronchoconstriction (EIB) in patients 6 years of age and older

Detailed Afineday dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep this medicine in the original bottle. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Afineday are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Afineday if you are allergic to its components or to aspirin. Do not take Afineday if you use Afineday while you are pregnant or have nurseling. You should not use Afineday for exercise-induced bronchoconstriction if you already take Afineday to prevent symptoms of allergy or asthma. Try to be careful using Afineday if you take phenobarbital (such as Solfoton, Luminal), rifampin (such as Rifamate, Rifadin, Rimactane, Rifater). It can be dangerous to use Afineday if you suffer from or have a history of phenylketonuria, liver disease. Avoid any activities such as driving or operating machinery while taking Afineday. It can be dangerous to stop Afineday taking suddenly.

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Univariate and multivariate logistic regression analyses were conducted to examine whether substantial conjunctival or lid bioburden, subject demographics, lens-wearing history, symptoms, and biomicroscopic signs were associated with lens bioburden. Comparison of power water--assisted and traditional liposuction: a prospective randomized trial of postoperative pain. Concern exists regarding whether these functions can be generalized to other populations. The frequency difference between the beams is essentially more than the reverse of the response time of prometrium 200 mg the hologram. Treatment of both cells with 100 microM KNK437 before or after heat-treatment inhibited methylation of H3-Lys4, while methylation of H3 Lys9 remained unaffected. Incubation of HL-60 cells with 200 microM of EDTA suppressed cell proliferation, and induced differentiation assessed by reductivity of nitro blue tetrazolium and activity of alpha-naphthyl butyrate esterase. The parallel distributed processing approach to semantic cognition. Acute intermittent hepatic porphyria: a cause of unexplained abdominal pain. Supplementation with exogenous antioxidants, including phenolic compounds from plant sources, may help to restore the pro-oxidative/antioxidative balance. Esters caused the release of acridine orange that selectively accumulates in the phagolysosome-like food vacuole of the parasite, attesting the ostensible destruction of this organelle by osmotic lysis.

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In this species, females have a short reproductive life that does not exceed 4 months. With the optimal conditions, the time of analysis was decreased from 69 to 40 min. In FTD, the presence of many of the behavioral disorders was associated with risperdal consta dose range decreased volume in right-hemispheric regions. Although kidney agenesis or dysgenesis has been observed in mice lacking functional ret, no clinically relevant kidney abnormalities have been reported in individuals with known RET mutations and familial medullary thyroid carcinoma (FMTC). The abundant proteolytic plasminogen (Plg)/plasmin system is important in several physiological functions in mammals and also engaged by a number of pathogenic microbial species to increase tissue invasiveness or to obtain nutrients. These findings indicate that persons with fibromyalgia display altered perception of both pressure and thermal stimulation, even at innocuous levels. This finding demonstrates how the variability found in routine clinical perimetry can be reduced through changes to the way in which the stimuli are presented and the way in which the patient responds. Radioresistance of mutants of Aspergillus giganteus (Wehm.) with various photosensitivity. Isolated ECM detected on prenatal scans has a favourable outcome, while DWC is associated with a very high chance of a poor prognosis. Hierarchical path analysis of deer responses to direct and indirect effects of climate in northern forest.

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