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Acloriv (Acyclovir)
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Acloriv

Acloriv is an antiviral medication that stops a protein (an enzyme called DNA polymerase) in the herpes simplex virus (HSV) and varicella-zoster virus (VZV). Without this enzyme, the virus can't make copies of itself.

Other names for this medication:
Accrivir, Aciherpin, Acirax, Acloriv, Aclovir, Acvirall, Acvirax, Acycloguanosine, Acyclor, Acyclovir, Alovir, Cevirin, Civir, Clovir, Clovirax, Clyvir, Cutivir, Cycloex, Cyclopiz, Docvir, Herperax, Herpex, Herpovir, Herzovir, Lovir, Lyrovir, Nisivir, Ocurax, Ocuvir, Okavir, Ophtrhovir, Optiviral, Oveer, Psyvir, Ridoherp, Rovir, Rowapil, Setuvir, Spaclovir, Virclo, Virex, Viroderm, Virucid, Vivorax, Zovir, Zoylex

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Also known as: Acyclovir

Description

Acyclovir belongs to the family of medicines called antivirals, which are used to treat infections caused by viruses. Usually these medicines work for only one kind or group of virus infections.

Acyclovir is used to treat the symptoms of chickenpox, shingles, herpes virus infections of the genitals (sex organs), the skin, the brain, and mucous membranes (lips and mouth), and widespread herpes virus infections in newborns. Acyclovir is also used to prevent recurrent genital herpes infections. Although acyclovir will not cure herpes, it does help relieve the pain and discomfort and helps the sores (if any) heal faster.

Acyclovir may also be used for other virus infections as determined by your doctor. However, it does not work in treating certain virus infections, such as the common cold.

Acyclovir is available only with your doctor's prescription.

Dosage

Patient information about the treatment of herpes, chickenpox, or shingles is available with this medicine. Read it carefully before using this medicine.

Acyclovir is best used as soon as possible after the symptoms of herpes infection or shingles (for example, pain, burning, blisters) begin to appear.

If you are taking acyclovir for the treatment of chickenpox, it is best to start taking acyclovir as soon as possible after the first sign of the chickenpox rash, usually within one day.

Acyclovir capsules, tablets, and oral suspension may be taken with meals or on an empty stomach.

Acyclovir is best taken with a full glass (8 ounces) of water.

If you are using acyclovir oral suspension, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your herpes infection, chickenpox, or shingles, keep taking acyclovir for the full time of treatment, even if your symptoms begin to clear up after a few days. Do not miss any doses. However, do not use this medicine more often or for a longer time than your doctor ordered.

If you are taking acyclovir capsules, tablets, or oral suspension, you should drink plenty of water to avoid becoming dehydrated.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules, oral suspension, or tablets): For treatment of genital herpes: Adults and children 12 years of age and older—200 milligrams (mg) five times a day for ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For prevention of recurrent outbreaks of genital herpes infections: Adults and children 12 years of age and older—200 to 400 mg two to five times a day for five days or up to twelve months, depending on how often your outbreaks of infection occur. Children up to 12 years of age—Use and dose must be determined by the doctor. For treatment of chickenpox: Adults and children who weigh over 88 pounds (40 kilograms)—800 mg four times a day for five days. Children 2 years of age and older and weighing 88 pounds (40 kilograms) or less—Dose is based on body weight and must be determined by the doctor. The usual dose is 20 mg per kilogram (kg) of body weight, up to 800 mg, four times a day for five days. Children up to 2 years of age—Use and dose must be determined by the doctor. For treatment of shingles: Adults and children 12 years of age and older—800 mg five times a day for seven to ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For injection dosage form: For treatment of herpes of the brain, genitals, or mucous membranes, or for the treatment of shingles: Adults and children 12 years of age and older—Dose is based on body weight and must be determined by the doctor. The usual dose is 5 to 10 mg of acyclovir per kg (2.3 to 4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period, and repeated every eight hours for five to ten days. Children up to 12 years of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg to 20 mg of acyclovir per kg (4.5 mg to 9.1 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for seven to ten days. For treatment of widespread herpes virus infection in newborns: Infants from birth to 3 months of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg of acyclovir per kg (4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for ten days.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Acloriv dosage information

Side effects

The most common side effects associated with Acloriv are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

A limited number of studies have been done using oral acyclovir in children, and it has not caused different effects or problems in children than it does in adults.

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Central injection of alpha-melanocyte-stimulating hormone (alpha-MSH) decreases food intake, suggesting a role for this peptide in the mediation of satiety. Cerebrovascular accidents (CVAs), transient ischemic attacks (TIAs), and peripheral arterial disease (PAD) frequently coexist with coronary artery disease (CAD) and were previously reported to adversely affect the prognosis of patients with chronic CAD. However, no effect was observed on HMGR activity or its mRNA indicating that they must be regulated by a separate sinus gland peptide. Ceramide 2 and ceramide 5 were detected in the nanomolar range at serum dilutions of up to 1:100 by dot blot and thin-layer immunostaining. USP19-deubiquitinating enzyme regulates levels of major myofibrillar proteins in L6 muscle cells. After a follow-up period of 10 months and 8 months for the 2 first cases, temporalis reinnervation by the facial nerve could be observed. Postoperatively, she developed bleeding secondary to a disseminated intravascular coagulopathy. Using intrinsic tryptophan as a molecular probe and from mutation studies, we ascertained the negligible contribution to solvation by protein sidechains and observed that the hydration dynamics at the active site occur in 0.47-0.67 and 10.8-13.2 ps. The glycoclusters obtained were tested for their relative inhibitory potency against the binding of yeast mannan to concanavalin A by solid-phase enzyme-linked lectin assays (ELLA) using methyl alpha-D-mannopyranoside as a standard. Tuberin: a stimulus-regulated tumor suppressor protein controlled by a diverse array of receptor tyrosine kinases and G protein-coupled receptors.

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Cervical cancer beliefs and pap test screening practices among Chinese American immigrants. The former analyzed in a Poisson regression approach, the latter in a generalized linear regression model. The sensitivity of effluent COD and nitrogen, TSS in the reactor and membrane flux with respect to each parameter (K(h), mu(H), K(S), K(NHH), K(NOH), b(H), Y(H), mu(A), K(NHA), b(A), Y(A), K(m) and alpha) was investigated by model simulation. There were 165 genes and expressed sequence tags, some of which have never been linked to drug resistance, that were up- or down-regulated at least 2-fold in all resistant sub feldene 20 mg suppository -lines when compared with SW1990. Evaluation of individual patient responses to position changes in the clinical setting is encouraged until further studies using more heterogenous populations can provide more definitive guidance. Among nulliparous females, montane voles attained receptivity with less male contact than prairie voles. Much effort has been expended on improving therapies that are expected to preserve bone mass and thus decrease fracture risk.

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However, acidic residue substitutions at the corresponding activation loop sites in B-Raf are sufficient to confer constitutive activity. The strategies involved in the development of HIV protease inhibitors are discussed. Protein modifications, such as carbonylation, nitration and formation of lipid peroxidation adducts, e.g. Patients with a history of either any febrile seizures, or complex, or prolonged febrile seizures, did not have greater hypometabolism ipsilateral to the epileptic focus than did patients without a febrile seizure history. Interestingly, adding exogenous IL-12 induced the generation of interferon-gamma (IFN-gamma)-secreting TH1 effectors and reverted the anergic profile in a secondary response. Northern blot analysis shows it is widely expressed in human tissues. Coinciding derangements are probably responsible for this expansion: increased proximal tubular reabsorption, inadequate activation of the renin-angiotensin zebeta dosing system and impaired renal autoregulation. Using the calibration curve, the concentrations in the tested samples were calculated at 2 x 10(5) to 10(6) individuals per mg of fresh midrib.

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Various considerations of the anti-ECT (electroconvulsive therapy) vogue. Preliminary can i drink alcohol after taking clomid studies have shown that P-dendrimers of series 1 and 2, possessing N,N-diethyl-ethylenediamine hydrochloride functions at the surface, show rather moderate cytotoxicity toward HeLa, HEK 293, and HUVEC cells in a standard MTT assay in serum-containing medium, generally lower than lipofectin. Inverse correlation between SMN1 and SMN2 copy numbers: evidence for gene conversion from SMN2 to SMN1. The expression of the apoptosis inhibitory protein, Bcl-2, is increased in naturally senescing human fibroblasts and upon induction of their senescence-like growth arrest by oxidative stress, implying its role in maintaining their extended viability. The investigation was carried out by reviewing relevant studies of neurochemistry and cognition. Analyses were performed by means of the intraclass correlation coefficients (ICCs). National quality control programme in Indian clinical laboratories. Decision aids are important adjuncts for counseling women with early-stage breast cancer. Ultrastructural cytochemistry reveals that the cortical granules are composed of glycoprotein. We report a 53-year-old man with familial hypertrophic restrictive cardiomyopathy who presented with right heart failure and end-stage liver failure and required combined orthotopic heart and liver transplantation.

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Effect of astigmatism on states of polarization of aberrant stochastic electromagnetic beams in turbulent atmosphere. We apply this technique to probe the structure and dynamics of water and oil at the surface of calibrated macroporous systems, where similar surface dynamics effects have been observed. Metallic condylar prostheses in the setting of tumor resection and reconstruction involve significant risks. The RNase is unique in that it consists of two different nonglycoprotein subunits with a molecular weight of 27 and 29 kDa, respectively. Recently, cultured autologous chondrocytes have been proposed as a source to promote repair of deep cartilage defects.

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Six patients in our group had evidence of schistosomal disease during their pretransplant evaluation and were appropriately treated. Duration of results in chemotherapy of pulmonary tuberculosis, with special consideration of isoniazid. Serial magnetic resonance images in patient with the middle cerebral artery dissection. There was no can you have alcohol while on clomid correlation between the time from smoking cessation and any cellular component found in IS samples. Our data indicate that the deletion of genetic material may result in gain-of-function fusion proteins. The effects of UV radiation are mediated via direct damage to cellular DNA in the skin and suppression of image surveillance mechanisms. In an evaluation of the clinical effectiveness of pyridostigmine as an antagonist of d-tubocurarine-induced and pancuronium-induced neuromuscular blockade in patients anesthetized with a neurolept-nitrous oxide (N2O) technic, 60 adults received either d-tubocurarine (dTc) (N equals 30) or pancuronium (N equals 30).

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