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Acetazolamide

Acetazolamide is a prescription medicine used to treat the symptoms of Glaucoma, Acute Altitude Sickness, Congestive Heart Failure, Seizure, Epilepsy and Drug-Induced Edema. Acetazolamide may be used alone or with other medications. Acetazolamide is available as a generic medication.

Other names for this medication:
Abzole, Aceact, Acetamide, Acetamin, Acetariv, Acetazolamide, Actamid, Actamide, Actazid, Antilep, Axytex, Carbadac, Iopar, Mazetol, Mezapin, Synomax, Tegrital, Zolamide

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Description

Acetazolamide reduces the activity of a protein in your body called carbonic anhydrase. Blocking this protein can help reduce the build-up of certain fluids in the body.

Acetazolamide is used in people with certain types of glaucoma to reduce the amount of fluid in the eye, which decreases pressure inside the eye.

Acetazolamide is also used as a diuretic ("water pill") in people with congestive heart failure, to reduce the build-up of fluid in the body. This build-up is called edema.

Acetazolamide is also used to treat certain types of seizures, and to treat or prevent altitude sickness.

Dosage

Acetazolamide is available in tablets. The dosage depends on the disease and its prescribed treatmen. Glaucoma treatment: 250 mg to 1 gram per 24 hours in 2 or more smaller doses. In secondary glaucoma and before surgery in acute congestive (closed-angle) glaucoma, the usual dosage is 250 mg every 4 hours or, in some cases, 250 mg twice a day. Epilepsy treatment: The daily dosage is 8 to 30 mg per 2.2 pounds of body weight in 2 or more doses. Typical dosage may range from 375 to 1,000 mg per day. Congestive Heart Failure treatment: The usual dosage is 250 mg to 375 mg per day or 5 mg per 2.2 pounds of body weight, taken in the morning. Acetazolamide can be used by children. If you want to achieve most effective results do not stop taking Acetazolamide suddenly.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Acetazolamide are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Acetazolamide if you are allergic to it, or if you have:

severe liver disease, or cirrhosis; severe kidney disease; an electrolyte imbalance (such as acidosis or low levels of potassium or sodium in your blood); adrenal gland failure; or an allergy to sulfa drugs.

To make sure Acetazolamide is safe for you, tell your doctor if you have:

severe breathing problems; angle closure glaucoma; or if you also take aspirin in high doses.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Acetazolamide can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.

Acetazolamide is not approved for use by anyone younger than 18 years old.

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In November 2001, the University of Michigan hosted one of the first dialogues among international trade law scholars and scientists in the field of risk assessment with the goal of identifying critical areas of misunderstanding between the two fields. Sagittal images of the spinal cord were obtained at different times of the cardiac cycle in healthy volunteers, as well as in patients in whom the spinal cord either was tethered, was compressed, or contained an intramedullary lesion. This paper provides an appraisal of the sensor requirements and prospects available for the growing field of wearable medical sensors. From a qualitative point of view, the iridoidic pattern of the two samples was similar, since the same compounds (asperuloside, asperulosidic acid and deacetyl asperulosidic acid) were isolated. Expression of core binding factor 1 and osteoblastic markers in C2C12 cells induced by calcium phosphate ceramics in vitro. Despite numerous advances in the diagnosis and treatment of pancreatic cancer, its prognosis remains dismal and a new therapeutic approach is much needed. The attachment sites of A40L and A33E were located at the end of the minor and the major axes of the ellipsoidal contour of the molecule, respectively.

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